Targeted therapies are designed to work against specific vulnerabilities in a cancer cell.
The targeted therapy drug venetoclax is designed to block the function of the B-cell lymphoma-2 (Bcl-2) protein, which normally works to prevent cell death.
Venetoclax was first approved in 2016 for treating certain patients with chronic lymphocytic leukemia, which has high levels of Bcl-2. More recently, venetoclax has begun to show...
For patients with pancreatic cancer, the benefits from immunotherapy treatments with immune checkpoint inhibitors or cell therapies have been...
Last updated on November 6, 2023
Immunotherapy is a treatment option for a growing number of cancers. Unlike traditional treatments...
Minimal residual disease (MRD) is a term commonly used with blood cancers that describes a small fraction of cancer cells that remain or come back after treatment. MRD doesn’t cause symptoms and isn’t detectable by standard clinical tests, such as CT scans or blood tests.
In solid tumors, MRD can refer to cancer cells in the blood, small metastases in the body, or a small portion of the primary tumor remaining after treatment....
Layered on top of our genes is an additional set of information -- the epigenome, which is important for many cellular activities. Disruption...
Although a tumor may start from a single cancer cell, it can eventually become millions of cells with unique characteristics. This diversity...
All of the DNA in our cells is organized into complex structures called chromosomes, which consist of our genetic material coiled around many...
In the last decade, immunotherapy has become a viable treatment option for many cancer patients. Unlike radiation and chemotherapy, immunotherapy...
Medullary thyroid cancer is a rare cancer diagnosed in about 1,200 patients annually in the U.S. Because it’s often a silent disease, many...
Studying new cancer therapies through clinical trials is essential for progress in cancer care. Phase I clinical trials are designed to evaluate...
In cancer, there are often large-scale deletions, rearrangements or other disruptions to our genetic information, which lead to a phenomenon...
Diagnostic imaging is a powerful tool for clinicians and researchers to see cancer in the body, enabling them to distinguish between benign...
Does social distancing effectively prevent the spread of SARS-CoV-2, the virus that causes COVID-19?
New research from MD Anderson...
After completing a course of treatment, there are few words that sound better to a patient than “complete remission.” It’s an indication that...