What is microsatellite instability?
When a patient receives a cancer diagnosis, one of the things their doctor might refer to is whether their cancer has microsatellite instability, or MSI. The prognosis and response to immunotherapy tend to be better for cancers that have high MSI, but why?
To learn more about MSI, we spoke with gastrointestinal medical oncologist and researcher Jason Willis, M.D., Ph.D.
First, what is a microsatellite?DNA is held...