Radiation therapy, the immune system and what’s ahead
Radiation therapy is often thought of as a treatment for localized cancer that hasn’t spread. But when paired with other therapies, it can be an effective option for patients with metastatic disease.
“It has long been recognized that there are opportunities to use drugs to make radiation therapy even more effective,” says Benjamin Schrank, M.D., Ph.D., a resident physician in Radiation Oncology and a member of the Wen Jiang Laboratory...
Liver regeneration: How the liver’s ability to recover plays into liver cancer surgery
Did you know that the liver is the only internal organ that can regenerate? But it doesn’t grow back like a salamander’s tail. When a portion...
Optimizing CAR T cell therapy with bridging radiation therapy
For many patients diagnosed with certain types of B-cell lymphoma, leukemia and multiple myeloma, chimeric antigen receptor (CAR) T cell therapy...
Peripheral neuropathy: Causes, symptoms and treatments
Many patients receive chemotherapy as part of their cancer treatment plan. These drugs have long shown benefits in extending patients’ lives, but they are also known for their side effects.
Chemotherapy-induced peripheral neuropathy is one of the most common side effects patients can experience. It can occur while a patient is receiving chemotherapy or after treatment is finished.
There are many approaches to...
4 things to know about marginal zone lymphoma
Lymphoma is often thought of as a cancer of lymph nodes, but it's actually a cancer of the lymphocytes. Lymphocytes are white blood cells...
Antibody drug conjugates: A shift in treatment options for solid tumors
Antibody drug conjugates have existed for years, but several recent advances are helping to refine how these cancer drugs work, expanding...
Spatial omics offer a deeper look at tertiary lymphoid structures in cancer
Tertiary lymphoid structures are highly organized clusters of immune cells that form in non-lymphoid tissues. They’re often found at sites...
How BTK inhibitors treat mantle cell lymphoma
B cells are an important part of the immune system. One of their jobs is to neutralize the threat from a foreign invader known as a pathogen...
LAG-3 inhibitors: A new type of immunotherapy
Immunotherapy harnesses the natural power of the immune system and enhances its response to cancer. Immune checkpoint inhibitors are the most...
RET inhibitors: A treatment for any RET-altered cancer
Cancer research is advancing rapidly, and patients are benefitting from new therapies faster than ever. One example is a type of targeted...