Over the last year and a half, Shams Peerbhai has tried just about everything to cope with peripheral neuropathy, a cancer treatment side effect that commonly causes tingling, burning, weakness or numbness in the hands and/or feet.

Now, the stage III colorectal cancer survivor is hoping a neuromodulation clinical trial eases his pain.

“I've already been through so much, I'm willing to try anything that works,” he...