Advanced ovarian cancer most commonly metastasizes to the omentum, a layer of fatty tissue that wraps around and protects internal organs in the abdomen, but the reasons for this have not been well-understood. In a new study, MD Anderson researchers discovered that a protein called omentin, or ITLN1, works to prevent metastasis of the cancer cells, but it is lost as the cancer develops.
Their preclinical findings, published in...
A team of researchers from across five disciplines at MD Anderson recently published the largest prospective study on breast implant associated...
MD Anderson surgeons have found a way to reduce pain and opioid use for lung cancer patients undergoing a lung...
The American Association for Cancer Research (AACR) is recognizing the founding members of The Cancer Genome Atlas (TCGA) and the current project team with 2020 AACR Team Science Awards. These teams will be honored during the AACR Virtual Annual Meeting II on June 24.
The Cancer Genome Atlas was launched in 2006 as a joint endeavor between the National Cancer Institute (NCI) and the National Human...
MD Anderson researchers have discovered that metastatic cancer cells in the brain upregulate expression of the EZH2 gene to activate a previously...
Researchers at MD Anderson have discovered that cancer-associated fibroblasts (CAF) help fuel the growth of breast tumors. Their findings...
Two studies presented at the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting highlighted MD Anderson’s commitment to holistic...
Updated results from two MD Anderson clinical trials presented at the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting indicate...
Findings from three studies led by researchers at MD Anderson suggest that new combination therapies are safe and effective against various...
Two studies led by MD Anderson researchers explore advancements in CAR T cell therapy for non-Hodgkin lymphomas. CAR T cell therapy is commonly...
Several MD Anderson-led studies at the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting focus on using immunotherapy to provide...
Brian Odle has now overcome four cancer diagnoses in his life, thanks to inheriting a mutation in the TP53 gene. This inherited condition...
Julia Pitts tried all the standard treatment options with her local physicians after she was diagnosed with metastatic uterine cancer in 2015...
Mutations in the BRCA 1 or 2 genes significantly increase an individual’s risk of developing breast cancer, as well as several other cancer...
Strategies to procure high-quality core-needle biopsy (CNB) specimens are critical for making basic tissue diagnoses and for ancillary testing...
In an analysis of three clinical trials, the targeted therapy larotrectinib resulted in a 79% overall response rate and median overall survival...
A deep sequencing study of brain metastases from MD Anderson revealed many similarities but also distinct differences relative to the primary...
An MD Anderson Phase I clinical trial demonstrated that a combination therapy using WNT974, a drug that targets the WNT pathway in cancer,...
A Phase I chemoprevention clinical trial led by MD Anderson researchers found that naproxen, an over-the-counter anti-inflammatory drug, is...
Results from a clinical trial led by MD Anderson researchers showed that combining the immunotherapy checkpoint inhibitor drug durvalumab...
MD Anderson researchers have identified potential biomarkers for the response of high-grade serous ovarian cancers (HGSC) to surgical resection...
Triple combination therapy kills glioblastoma in mice by putting an “eat me” signal to the immune system on the surface of the brain tumor...
Combining two immunotherapies caused tumor rejection in mouse models of pancreatic cancer and provided long-term immune memory that prevented...
In patients with leukemia, complete remission after treatment is currently defined by the absence of cancer cells in a bone marrow biopsy...
Triple-negative breast cancer (TNBC) is an aggressive disease that makes up roughly 15% to 20% of breast cancer diagnoses. Standard chemotherapy...
“Trainees at the Ph.D. and postdoctoral level are leaving the academic research track at alarming rates, and disproportionately if they’re...
Surveying the landscape of T cell presence and activity across the lungs of patients treated for localized non-small cell lung cancer, researchers...
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon form of ALCL that was first reported in 1996. The U.S....
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a type of cancer treatment in which surgeons apply heated chemotherapy...
While U.S. cervical cancer rates have fallen by 70% since the 1950s thanks to the Pap test and national screening programs, the disease...
Immunotherapies have brought the potential for long-term remission and even cures to patients with many cancer types, but the benefits have...
President Donald Trump today announced his intent to appoint Hussein Tawbi, M.D., Ph.D., associate professor and deputy chairman of Melanoma...
Chimeric antigen receptor (CAR) T cells were approved by the Food and Drug Administration (FDA) to treat relapsed and refractory large B-cell...
Cellular therapies have emerged as an effective new therapy for patients with certain types of cancer, and MD Anderson has played an important...
Researchers from MD Anderson have revealed how glioma cells move and infiltrate the brain, providing a new potential treatment pathway to...
A study published in JAMA comparing adverse event outcomes by treatment type for patients with localized prostate cancer reveals most...
MD Anderson has created a new research platform to drive the discovery of new therapeutic agents for patients with leukemia by investigating...