Details emerge in link between body mass index, chemotherapy response
MD Anderson researchers discussed new data on the connection between body mass index (BMI) and response to presurgical chemotherapy in patients with inflammatory breast cancer during a poster discussion at the 36th annual CTRC-AACR San Antonio Breast Cancer Symposium.
The study examined 1,002 cases of patients with inflammatory breast cancer or locally advanced non-inflammatory breast cancer between 2006-2012. It was the first...
Drug combo helps 95% of CLL clinical trial patients; ibrutinib resistance studied
Even as the targeted therapy ibrutinib makes its way through clinical trials as a single treatment for chronic lymphocytic leukemia (CLL),...
Super gene MUC5B provides mucus required for strong airway defense
In a typical day, each of us swallows 30 milliliters of mucus from our lungs. A mucus blanket is swept from the most distant airways up the...
Researchers call on Sleeping Beauty to arm T cells against cancer #ASH13
When it comes to equipping T cells, the immune system's attack dogs, to find and kill cancer cells, Sleeping Beauty just might be a heroine in the story.
Genetically altering T cells to recognize a surface protein called CD19 and destroy cells that wear it has shown great promise for treating blood cancers, most recently in clinical trials presented during this week at the 55th American Society of Hematology (ASH) Annual Meeting...
New targeted therapy halts CLL for more than 2 years and counting
Patients on an extended clinical trial of the targeted therapy ibrutinib have their relapsed or resistant chronic lymphocytic leukemia stymied...