Activating leukemia stem cells makes chemotherapy more effective...
Acute myeloid leukemia (AML) is a hard-to-treat cancer in which certain leukemia stem/progenitor cells (LSPCs) hide in the bone marrow...
Study identifies potential biomarker for treatment response...
Glioblastoma, the most common type of central nervous system tumor, is generally resistant to immune checkpoint blockade, highlighting...
Comprehensive spatial map provides insights into pancreatic...
Pancreatic cancer is notoriously difficult to treat, resulting in a five-year survival rate of roughly 12%. Approximately half of...
Triplet regimen is well tolerated by patients with AML but does...
Patients with acute myeloid leukemia (AML) who have high-risk genetic changes and those with relapsed disease have poor outcomes with...
Gut microbiome impacts CAR T cell therapy responses, side...
The gut microbiome has been linked to chimeric antigen receptor (CAR) T cell therapy response and related toxicities, but few...
Pilot nursing study explores physical activity during and...
Hematopoietic stem cell transplantation (HSCT) is a vital treatment for blood cancers, but it is also an intense therapy with lengthy...
CLL-derived exosomes alter body’s immune and hematopoietic...
Immunosuppression, neutropenia and anemia can occur in patients with chronic lymphocytic leukemia (CLL) – a type of blood cancer that...
Agents that cause ‘copper overload’ can overcome...
Radiation therapy, or radiotherapy, can successfully treat multiple cancers, but some patients develop resistance to this treatment,...
Novel blood-based biomarker identified in newly diagnosed...
Inflammation in patients with acute myeloid leukemia (AML) can impact responses to certain treatments, underscoring a need for better...
Landmark study maps spatial organization of...
Landmark study maps spatial organization of cancer-associated fibroblasts across cancers
Cancer-associated fibroblasts (CAFs) are...
Combination therapy shows no added survival benefit in...
Patients with intermediate-risk cervical cancer often receive chemotherapy with radiation therapy after surgery, but the added benefit...
BCMA-directed CAR T cell therapy is safe in patients with...
Due to the risk of associated neurotoxicities, some clinicians are hesitant to consider B-cell maturation antigen (BCMA)-directed...
Whole-slide imaging allows real-time remote diagnosis for...
Pathologists traditionally use light microscopy to evaluate stained frozen sections of lymph nodes obtained during surgery in...
Study provides genomic insights into treatment resistance...
SMARCA4 – a gene that helps in chromatin remodeling – frequently is mutated in lung cancer, leading to immunotherapy resistance and...
Phase II study identifies potential biomarkers in...
Cytotoxic chemotherapy is the standard of care for patients with unresectable and metastatic squamous cell carcinoma of the anal canal...
Bioinformatics chatbot can analyze large-scale cancer...
Comprehensive cancer omics initiatives like The Cancer Genome Atlas (TCGA) provide a wealth of DNA and RNA data, but little is known...
Combination therapy yields strong long-term overall...
Intensive chemotherapy remains the standard treatment option for medically fit patients with newly diagnosed acute myeloid...
Study offers insights into evolutionary process driving...
Pancreatic cancer is hard to treat because of its heterogeneity, a characteristic frequently sustained by the ability of cells to...
Researchers identify epigenetic biomarker for breast cancer...
Cancer cells that initiate metastasis at secondary sites often enter a dormant state, allowing them to evade treatment and later...
Surgery enhances immunotherapy in advanced kidney cancer
Patients with advanced solid tumors are usually ineligible for surgery. However, surgically removing the primary tumor in preclinical...