Services
Antibody Based Proteomics
Peggy Sue Nanoimmunoassay
Capillary electrophoresis-based immunoassay. Separate proteins by molecular weight (size assay) or isoelectric point (charge assay). Provides greater sensitivity than MS and uses low sample volumes. An excellent option for antibody validation and resolution and quantitation of proteoforms / post-translational modifications.
Pricing:
| Internal | Academic In-Network | Academic (Out of Network) | Non-academic | |
|---|---|---|---|---|
| New assay setup, per day | $600/day | $638.30/day | $1,034.04/sample | $1,197.38/sample |
| Production of HIGH- and LOW-expresser lysates of desired protein target | $3,000 | $3,191.49 | $5,170.21 | $5,986.91 |
| Antibody validation, 1-5 antibodies | $800 | $851.06 | $1,378.72 | $1,596.51 |
| Nanoimmunoassay Cycle 1 | $800 | $851.06 | $1,378.72 | $1,596.51 |
| Nanoimmunoassay Cycle 2-8 | $300/cycle | $319.15/cycle | $517.02/cycle | $598.69/cycle |
Alamar Biosciences NULISAseq
Measurement of 253 cytokines, chemokines, inflammation markers with unparalleled sensitivity. Currently, the platform is optimized for plasma samples, but we're developing protocols for other matrices including cell culture media, cells, tissues, and urine (please contact us for status of these protocols).
Pricing:
| Internal | Academic In-Network | Academic (Out of Network) | Non-academic | |
|---|---|---|---|---|
| Inflammation Panel |
$200/sample | $212.77/sample |
$344.68/sample | $399.13/sample |
MS-Based Proteomics, Label-Free
Single-shot Proteome Profiling
Global profiling of proteins (>2,000) from tissue/cell/biofluids with a single LC-MS/MS run.
Pricing:
| Internal | $235.00/sample |
| Academic In-Network | $250.00/sample |
| Academic (Out of Network) | $405.00/sample |
| Non-academic | $468.98/sample |
DIA Profiling
Global profiling of proteins (>6,000) from tissue/cell/biofluids via a data independent acquisition (DIA) workflow.
Pricing:
| Internal | $750.00/sample |
| Academic In-Network | $797.87/sample |
| Academic (Out of Network) | $1,292.55/sample |
| Non-academic | $1,496.73/sample |
Protein ID / IP-MS
Identification of proteins from gel bands or immunoprecipitates.
Pricing:
| Internal | $275.00/sample |
| Academic In-Network | $292.55/sample |
| Academic (Out of Network) | $473.94/sample |
| Non-academic | $548.80/sample |
Phosphorylation Analysis (Phospho-proteomics)
Profiling of phosphorylated proteins (>3,500) following phospho-enrichment.
Pricing:
| Internal | $335.00/sample |
| Academic In-Network | $356.38/sample |
| Academic (Out of Network) | $575.34/sample |
| Non-academic | $668.54/sample |
Ubiquitination Analysis
Profiling of ubiquitinated proteins following ubiquitin enrichment.
Pricing:
| Internal | $535.00/sample |
| Academic In-Network | $569.15/sample |
| Academic (Out of Network) | $922.02/sample |
| Non-academic | $1,067.67/sample |
MS-Based Proteomics, TMT
TMT Sample Preparation
Sample preparation for tandem mass tag (TMT)-based global profiling of proteins (base fee).
Pricing:
| Internal | $600.00/sample |
| Academic In-Network | $638.30/sample |
| Academic (Out of Network) | $1,034.04/sample |
| Non-academic | $1,197.38/sample |
HPLC Fractionation for TMT, 20 fractions
Additional fee to produce 20 fractions per sample for 1 batch of TMT (6, 11, 16, or 18 samples).
Pricing:
| Internal | $1,600.00 |
| Academic In-Network | $1,702.13 |
| Academic (Out of Network) | $2,756.45 |
| Non-academic | $3,193.02 |
HPLC Fractionation for TMT, 40 fractions
Additional fee to produce 40 fractions per sample for 1 batch of TMT (6, 11, 16, or 18 samples).
Pricing:
| Internal | $3,200.00 |
| Academic In-Network | $3,404.26 |
| Academic (Out of Network) | $5,514.89 |
| Non-academic | $6,386.04 |
TMT-based Phosphorylation Analysis, 1 fraction
Additional fee for phospho-enrichment of TMT-labeled samples, 1 fraction for 1 batch of TMT. Typically yields >3,500 phosphoproteins.
Pricing:
| Internal | $300.00/batch |
| Academic In-Network | $319.15/batch |
| Academic (Out of Network) | $517.02/batch |
| Non-academic | $598.69/batch |
TMT-based Phosphorylation Analysis, 10 fractions
Additional fee for phospho-enrichment of TMT-labeled samples, 10 fractions for 1 batch of TMT. Typically yields >8,000 phosphoproteins.
Pricing:
| Internal | $3000.00/batch |
| Academic In-Network | $3,191.49/batch |
| Academic (Out of Network) | $5,170.21/batch |
| Non-academic | $5,986.91/batch |
MS-Based Proteomics, Targeted
New Assay Development
Need more sensitivity? Targeted analysis with triple quadrupole MS leverages faster scan speeds to achieve greater sensitivity, and the addition of stable isotope-labeled peptides as internal standards add quantitative rigor and reproducibility. A new assay for most proteins can be developed with 3 days of labor, which includes optimization of a range of parameters including extraction/recovery. Challenging biological matrices (e.g., stool) and/or challenging analytes often require more time.
Pricing:
| Internal | Academic In-Network | Academic (Out of Network) | Non-academic | |
|---|---|---|---|---|
| Method development time | $600/day | $638.30/day | $1,034.04/sample | $1,197.38/sample |
| Routine sample analysis after method completion, including sample prep | $300.00/sample | $319.15/sample | $517.02/sample | $598.69/sample |
Additional Services
Advanced Data Analysis
Our default reporting pipelines for each platform above continue to evolve, but sometimes users need additional, custom analysis (e.g., advanced statistical analyses, pathway analyses, multi-omic data integration). Our data science team is available to assist with such requests.
Pricing:
| Internal | Academic In-Network | Academic (Out of Network) | Non-academic |
|---|---|---|---|
| $200/hour | $212.77/hour | $344.68/hour | $399.13/hour |
Academic in-network institutions:
UT System
Baylor College of Medicine
Rice University
University of Houston
Texas A&M Institute of Biosciences and Technology (IBT)
Houston Methodist Research Institute (HMRI)