Publications
| Year | Title | Journal | Authors (First, Last) | PMID |
|---|---|---|---|---|
| 2018 | A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer |
Cancer Cell | Peng X, Mills GB | 29706454 |
| 2018 | EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation | Mol Cell | Lee JH, Lu Z | 29677490 |
| 2018 | Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8(+) T Cell Response. | J Immunol | Khong H, Overwijk WW | 29643190 |
| 2018 | Cancer Genome Atlas Research Network, Bathe OF, Liang H. Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. | Cell Rep | Peng X, Liang H | 29617665 |
| 2018 | Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress | Cancer Discov | Qian X, Lu Z | 29074724 |
| 2017 | Genome-wide identification and differential analysis of translational initiation. | Nat Commun | Zhang P, Chen Y | 29170441 |
| 2017 | A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer. | Cell Rep | Gong J, Han L | 29141226 |
| 2017 | JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. | J Clin Invest | Wang S, Lin C | 29130936 |
| 2017 | A murine preclinical syngeneic transplantation model for breast cancer precision medicine. | Sci Adv. | Federico L, Mills GB | 28439535 |
| 2017 | he LINK-A lncRNA interacts with PtdIns(3,4,5)P(3) to hyperactivate AKT and confer resistance to AKT inhibitors. | Nat Cell Biol. | Lin A, Yang L | 28218907 |
| 2017 | A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis. | Nat Cell Biol | Li C, Yang L | 28114269 |
| 2017 | Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy. | Cancer Lett. | Long Y, Kuo MT | 27913198 |
| 2016 | Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. | PLoS One. | Sasai K, Sen S | 27332895 |
| 2016 |
Corrigendum: A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation. | Nat Cell Biol. | Li X, Lu Z | 27230532 |
| 2016 | Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis. | Mol Cell. | Li X, Lu Z | 26942675 |
| 2016 | ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies. | Sci Signal | Ishizawa J, Andreeff M | 26884599 |
| 2016 | The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. | Nat Cell Biol. | Lin A, Yang L | 26751287 |
| 2016 | Phosphopeptide Enrichment by Covalent Chromatography After Solid Phase Derivatization of Protein Digests on Reversed Phase Supports | Methods Mol Biol | Nika H, Hawke DH | 26584917 |
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Note that this only lists MD Anderson publications from the last five years
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Pre-2015 Publications
Select a year below.
2015
1: Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH. Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer. Cancer Res. 2015 Nov 15;75(22):4949-59. doi: 10.1158/0008-5472.CAN-15-1215. Epub 2015 Nov 3. PubMed PMID: 26530902; PubMed Central PMCID: PMC4651787.
2: Zheng Y, Li X, Qian X, Wang Y, Lee JH, Xia Y, Hawke DH, Zhang G, Lyu J, Lu Z. Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation. Nat Cell Biol. 2015 Oct;17(10):1348-55. doi: 10.1038/ncb3222. Epub 2015 Aug 17. PubMed PMID: 26280537; PubMed Central PMCID: PMC4785887.
3: Cheung LW, Walkiewicz KW, Besong TM, Guo H, Hawke DH, Arold ST, Mills GB. Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium. Elife. 2015 Jul 29;4:e06866. doi: 10.7554/eLife.06866. PubMed PMID: 26222500; PubMed Central PMCID: PMC4518712.
4: Anishkin A, Vanegas JM, Rogers DM, Lorenzi PL, Chan WK, Purwaha P, Weinstein JN, Sukharev S, Rempe SB. Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase. J Mol Biol. 2015 Aug 28;427(17):2867-85. doi: 10.1016/j.jmb.2015.06.017. Epub 2015 Jul 2. PubMed PMID: 26142822.
5: Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK. XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. Clin Cancer Res. 2015 Jul 15;21(14):3286-97. doi: 10.1158/1078-0432.CCR-14-1953. Epub 2015 Apr 15. PubMed PMID: 25878333; PubMed Central PMCID: PMC4506247.
6: Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W. Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study. Cancer. 2015 Jul 15;121(14):2411-21. doi: 10.1002/cncr.29344. Epub 2015 Apr 1. PubMed PMID: 25832466; PubMed Central PMCID: PMC4490036.
7: Li X, Wang W, Wang J, Malovannaya A, Xi Y, Li W, Guerra R, Hawke DH, Qin J, Chen J. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol Syst Biol. 2015 Jan 21;11(1):775. doi: 10.15252/msb.20145504. PubMed PMID: 25609649; PubMed Central PMCID: PMC4332150.
2014
1: Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB. Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. Cancer Cell. 2014 Dec 8;26(6):863-879. doi: 10.1016/j.ccell.2014.10.010. PubMed PMID: 25490449; PubMed Central PMCID: PMC4261159.
2: Heinemann ML, Ilmer M, Silva LP, Hawke DH, Recio A, Vorontsova MA, Alt E, Vykoukal J. Benchtop isolation and characterization of functional exosomes by sequential filtration. J Chromatogr A. 2014 Dec 5;1371:125-35. PubMed PMID: 25458527.
3: Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, Park PK, Qin L, Wei Y, Hawke DH, Hung MC, Lin C, Yang L. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014 Nov 20;159(5):1110-1125. doi: 10.1016/j.cell.2014.10.013. Epub 2014 Nov 13. PubMed PMID: 25416949; PubMed Central PMCID: PMC4266991.
4: Jiang Y, Wang Y, Wang T, Hawke DH, Zheng Y, Li X, Zhou Q, Majumder S, Bi E, Liu DX, Huang S, Lu Z. PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells. Nat Commun. 2014 Nov 21;5:5566. doi: 10.1038/ncomms6566. PubMed PMID: 25412762; PubMed Central PMCID: PMC4259466.
5: Cheung LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB. Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors. Cancer Cell. 2014 Oct 13;26(4):479-94. doi: 10.1016/j.ccell.2014.08.017. Epub 2014 Oct 2. PubMed PMID: 25284480; PubMed Central PMCID: PMC4198486.
6: Nika H, Angeletti RH, Hawke DH. N-terminal protein characterization by mass spectrometry using combined microscale liquid and solid-phase derivatization. J Biomol Tech. 2014 Sep;25(3):77-86. doi: 10.7171/jbt.14-2503-001. PubMed PMID: 25187758; PubMed Central PMCID: PMC4136438.
7: Purwaha P, Lorenzi PL, Silva LP, Hawke DH, Weinstein JN. Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells. Metabolomics. 2014;10(5):909-919. Epub 2014 Feb 7. PubMed PMID: 25177232; PubMed Central PMCID: PMC4145215.
8: Lorenzi PL, Claerhout S, Mills GB, Weinstein JN. A curated census of autophagy-modulating proteins and small molecules: candidate targets for cancer therapy. Autophagy. 2014 Jul;10(7):1316-26. doi: 10.4161/auto.28773. Epub 2014 May 12. PubMed PMID: 24906121; PubMed Central PMCID: PMC4203555.
9: Purwaha P, Silva LP, Hawke DH, Weinstein JN, Lorenzi PL. An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid. Anal Chem. 2014 Jun 17;86(12):5633-7. doi: 10.1021/ac501451v. Epub 2014 Jun 5. PubMed PMID: 24892977; PubMed Central PMCID: PMC4063328.
10: Nika H, Hawke DH, Angeletti RH. N-terminal protein characterization by mass spectrometry after cyanogen bromide cleavage using combined microscale liquid- and solid-phase derivatization. J Biomol Tech. 2014 Apr;25(1):19-30. doi: 10.7171/jbt.14-2501-003. PubMed PMID: 24688320; PubMed Central PMCID: PMC3942260.
11: Nika H, Hawke DH, Angeletti RH. C-terminal protein characterization by mass spectrometry: isolation of C-terminal fragments from cyanogen bromide-cleaved protein. J Biomol Tech. 2014 Apr;25(1):1-18. doi: 10.7171/jbt.14-2501-001. PubMed PMID: 24688319; PubMed Central PMCID: PMC3942263.
12: Chan WK, Lorenzi PL, Anishkin A, Purwaha P, Rogers DM, Sukharev S, Rempe SB, Weinstein JN. The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells. Blood. 2014 Jun 5;123(23):3596-606. doi: 10.1182/blood-2013-10-535112. Epub 2014 Mar 21. PubMed PMID: 24659632; PubMed Central PMCID: PMC4047499.
13: Kruger S, Abd Elmageed ZY, Hawke DH, Wörner PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. Molecular characterization of exosome-like vesicles from breast cancer cells. BMC Cancer. 2014 Jan 27;14:44. doi: 10.1186/1471-2407-14-44. PubMed PMID: 24468161; PubMed Central PMCID: PMC3936808.
14: Jiang Y, Li X, Yang W, Hawke DH, Zheng Y, Xia Y, Aldape K, Wei C, Guo F, Chen Y, Lu Z. PKM2 regulates chromosome segregation and mitosis progression of tumor cells. Mol Cell. 2014 Jan 9;53(1):75-87. doi: 10.1016/j.molcel.2013.11.001. Epub 2013 Dec 5. PubMed PMID: 24316223; PubMed Central PMCID: PMC3955203.
2013
1: Jiang Y, Li X, Yang W, Hawke DH, Zheng Y, Xia Y, Aldape K, Wei C, Guo F, Chen Y, Lu Z. PKM2 regulates chromosome segregation and mitosis progression of tumor cells. Mol Cell. 2014 Jan 9;53(1):75-87. doi: 10.1016/j.molcel.2013.11.001. Epub 2013 Dec 5. PubMed PMID: 24316223; PubMed Central PMCID: PMC3955203.
2: Weinstein JN, Lorenzi PL. Cancer: Discrepancies in drug sensitivity. Nature. 2013 Dec 19;504(7480):381-3. doi: 10.1038/nature12839. Epub 2013 Nov 27. PubMed PMID: 24284624.
3: Chuang C, Pan J, Hawke DH, Lin SH, Yu-Lee LY. NudC deacetylation regulates mitotic progression. PLoS One. 2013 Sep 19;8(9):e73841. doi: 10.1371/journal.pone.0073841. eCollection 2013. PubMed PMID: 24069238; PubMed Central PMCID: PMC3777959.
4: Silva LP, Lorenzi PL, Purwaha P, Yong V, Hawke DH, Weinstein JN. Measurement of DNA concentration as a normalization strategy for metabolomic data from adherent cell lines. Anal Chem. 2013 Oct 15;85(20):9536-42. doi: 10.1021/ac401559v. Epub 2013 Oct 2. PubMed PMID: 24011029; PubMed Central PMCID: PMC3868625.
5: Nika H, Nieves E, Hawke DH, Angeletti RH. Phosphopeptide enrichment by covalent chromatography after derivatization of protein digests immobilized on reversed-phase supports. J Biomol Tech. 2013 Sep;24(3):154-77. doi: 10.7171/jbt.13-2403-004. PubMed PMID: 23997662; PubMed Central PMCID: PMC3750845.
6: Nika H, Nieves E, Hawke DH, Angeletti RH. Optimization of the β-elimination/michael addition chemistry on reversed-phase supports for mass spectrometry analysis of O-linked protein modifications. J Biomol Tech. 2013 Sep;24(3):132-53. doi: 10.7171/jbt.13-2403-005. PubMed PMID: 23997661; PubMed Central PMCID: PMC3703673.
7: Nika H, Nieves E, Hawke DH, Angeletti RH. C-terminal protein characterization by mass spectrometry using combined micro scale liquid and solid-phase derivatization. J Biomol Tech. 2013 Apr;24(1):17-31. doi: 10.7171/jbt.13-2401-003. PubMed PMID: 23543807; PubMed Central PMCID: PMC3518879.
8: Lu J, Ye X, Fan F, Xia L, Bhattacharya R, Bellister S, Tozzi F, Sceusi E, Zhou Y, Tachibana I, Maru DM, Hawke DH, Rak J, Mani SA, Zweidler-McKay P, Ellis LM. Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. Cancer Cell. 2013 Feb 11;23(2):171-85. doi: 10.1016/j.ccr.2012.12.021. Epub 2013 Jan 31. PubMed PMID: 23375636; PubMed Central PMCID: PMC3574187.
9: Angelo LS, Maxwell DS, Wu JY, Sun D, Hawke DH, McCutcheon IE, Slopis JM, Peng Z, Bornmann WG, Kurzrock R. Binding partners for curcumin in human schwannoma cells: biologic implications. Bioorg Med Chem. 2013 Feb 15;21(4):932-9. doi: 10.1016/j.bmc.2012.12.008. Epub 2012 Dec 13. PubMed PMID: 23294827.
2012
1: Angelo LS, Maxwell DS, Wu JY, Sun D, Hawke DH, McCutcheon IE, Slopis JM, Peng Z, Bornmann WG, Kurzrock R. Binding partners for curcumin in human schwannoma cells: biologic implications. Bioorg Med Chem. 2013 Feb 15;21(4):932-9. doi: 10.1016/j.bmc.2012.12.008. Epub 2012 Dec 13. PubMed PMID: 23294827.
2: Nika H, Lee J, Willis IM, Angeletti RH, Hawke DH. Phosphopeptide characterization by mass spectrometry using reversed-phase supports for solid-phase β-elimination/Michael addition. J Biomol Tech. 2012 Jul;23(2):51-68. doi: 10.7171/jbt.2012-2302-002. PubMed PMID: 22951960; PubMed Central PMCID: PMC3324170.
3: Dufour E, Gay F, Aguera K, Scoazec JY, Horand F, Lorenzi PL, Godfrin Y. Pancreatic tumor sensitivity to plasma L-asparagine starvation. Pancreas. 2012 Aug;41(6):940-8. doi: 10.1097/MPA.0b013e318247d903. PubMed PMID: 22513289.
2011
1: Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F. PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo. Blood. 2011 Sep 15;118(11):3107-18. doi: 10.1182/blood-2011-04-349670. Epub 2011 Jul 29. PubMed PMID: 21803845; PubMed Central PMCID: PMC3291494.
2: Friedman DB, Andacht TM, Bunger MK, Chien AS, Hawke DH, Krijgsveld J, Lane WS, Lilley KS, MacCoss MJ, Moritz RL, Settlage RE, Sherman NE, Weintraub ST, Witkowska HE, Yates NA, Turck CW. The ABRF Proteomics Research Group studies: educational exercises for qualitative and quantitative proteomic analyses. Proteomics. 2011 Apr;11(8):1371-81. doi: 10.1002/pmic.201000736. Epub 2011 Mar 11. PubMed PMID: 21394914.
3: Claerhout S, Lorenzi PL, Weinstein JN, Mills GB. Modulating of autophagy and its potential for cancer therapy. Drugs Future. 2011;36(12). doi: 10.1358/dof.2011.036.12.1711892. PubMed PMID: 25419038; PubMed Central PMCID: PMC4239665.
2010
1: Jin Q, Yuan LX, Boulbes D, Baek JM, Wang YN, Gomez-Cabello D, Hawke DH, Yeung SC, Lee MH, Hortobagyi GN, Hung MC, Esteva FJ. Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells. Breast Cancer Res. 2010;12(6):R96. doi: 10.1186/bcr2777. Epub 2010 Nov 16. PubMed PMID: 21080941; PubMed Central PMCID: PMC3046439.
2: Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5112-7. doi: 10.1073/pnas.0915141107. Epub 2010 Feb 26. PubMed PMID: 20190181; PubMed Central PMCID: PMC2841949.
3: Chen LS, Du-Cuny L, Vethantham V, Hawke DH, Manley JL, Zhang S, Gandhi V. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 1;79(5):669-77. doi: 10.1016/j.bcp.2009.09.028. Epub 2009 Oct 6. PubMed PMID: 19814999; PubMed Central PMCID: PMC2812641.
2009
1: Chen LS, Du-Cuny L, Vethantham V, Hawke DH, Manley JL, Zhang S, Gandhi V. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 1;79(5):669-77. doi: 10.1016/j.bcp.2009.09.028. Epub 2009 Oct 6. PubMed PMID: 19814999; PubMed Central PMCID: PMC2812641.
2: Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9. PubMed PMID: 19741151; PubMed Central PMCID: PMC2784710.
3: Lorenzi PL, Reinhold WC, Varma S, Hutchinson AA, Pommier Y, Chanock SJ, Weinstein JN. DNA fingerprinting of the NCI-60 cell line panel. Mol Cancer Ther. 2009 Apr;8(4):713-24. doi: 10.1158/1535-7163.MCT-08-0921. PubMed PMID: 19372543; PubMed Central PMCID: PMC4020356.
4: Lorenzi PL, Weinstein JN. Asparagine synthetase: a new potential biomarker in ovarian cancer. Drug News Perspect. 2009 Jan-Feb;22(1):61-4. doi: 10.1358/dnp.2009.22.1.1303820. Review. PubMed PMID: 19209300; PubMed Central PMCID: PMC4096155.