Publications
Notable High Impact Publications
Hematogenous Metastasis of Ovarian Cancer: Rethinking Mode of Spread. Sunila Pradeep, Seung W. Kim, Sherry Y. Wu, Masato Nishimura, Pradeep Chaluvally-Raghavan, Takahito Miyake, Chad V. Pecot, Sun-Jin Kim, Hyun Jin Choi, Farideh Z. Bischoff, Julie Ann Mayer, Li Huang, Alpa M. Nick, Carolyn S. Hall, Cristian Rodriguez-Aguayo, Behrouz Zand, Heather J. Dalton, Thiruvengadam Arumugam, Ho Jeong Lee, Hee Dong Han, Min Soon Cho, Rajesha Rupaimoole, Lingegowda S. Mangala, Vasudha Sehgal, Sang Cheul Oh, Jinsong Liu, Ju-Seog Lee, Robert L. Coleman, Prahlad Ram, Gabriel Lopez-Berestein, Isaiah J. Fidler, and Anil K. Sood. Cancer Cell 26, 77–91, July 14, 2014
RNAi Therapies: Drugging the Undruggable. S. Y. Wu, G. Lopez-Berestein, G. A. Calin, and A. K. Sood. Sci. Transl. Med. 6, 240ps7 (2014).
Tumour angiogenesis regulation by the miR-200 family. Chad V. Pecot, Rajesha Rupaimoole, Da Yang, Rehan Akbani, Cristina Ivan, Chunhua Lu, Sherry Wu, Hee-Dong Han, Maitri Y. Shah, Cristian Rodriguez-Aguayo, Justin Bottsford-Miller, Yuexin Liu, Sang Bae Kim, Anna Unruh, Vianey Gonzalez-Villasana, Li Huang, Behrouz Zand, Myrthala Moreno-Smith, Lingegowda S. Mangala, Morgan Taylor, Heather J. Dalton, Vasudha Sehgal, Yunfei Wen, Yu Kang, Keith A. Baggerly, Ju-Seog Lee, Prahlad T. Ram, Murali K. Ravoori, Vikas Kundra, Xinna Zhang, Rouba Ali-Fehmi, Ana-Maria Gonzalez-Angulo, Pierre P. Massion, George A. Calin, Gabriel Lopez-Berestein, Wei Zhang, and Anil K. Sood. Nat. Commun. 4:2427 doi: 10.1038/ncomms3427 (2013)
A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis. Massimo Masiero, Filipa Costa Simões, Hee Dong Han, Cameron Snell, Tessa Peterkin, Esther Bridges, Lingegowda S. Mangala, Sherry Yen-Yao Wu, Sunila Pradeep, Demin Li, Cheng Han, Heather Dalton, Gabriel Lopez-Berestein, Jurriaan B. Tuynman, Neil Mortensen, Ji-Liang Li, Roger Patient, Anil K. Sood, Alison H. Banham, Adrian L. Harris, Francesca M. Buffa. Cancer Cell 24, 1-13, 2013. PMID:23871637
In situ hybridization-based detection of microRNAs in human diseases. Xinna Zhang, Xiongbin Lu, Gabriel Lopez-Berestein, Anil K. Sood, and George Calin. MICRNAT.Vol1,12-23,DOI:10.2478/micrnat-2013-0002
Src activation by β-adrenoreceptors is a key switch for tumour metastasis. Guillermo N. Armaiz-Pena, Julie K. Allen, Anthony Cruz, Rebecca L. Stone, Alpa M. Nick, Yvonne G. Lin, Liz Y. Han, Lingegowda S. Mangala, Gabriel J. Villares, Pablo Vivas-Mejia, Cristian Rodriguez-Aguayo, Archana S. Nagaraja, Kshipra M. Gharpure, Zheng Wu, Robert D. English, Kizhake V. Soman, Mian M. K. Shahzad, Maya Zigler, Michael T. Deavers, Alexander Zien, Theodoros G. Soldatos, David B. Jackson, John E. Wiktorowicz, Madeline Torres-Lugo,Tom Young, Koen De Geest, Gary E. Gallick, Menashe Bar-Eli, Gabriel Lopez-Berestein, Steve W. Cole, Gustavo E. Lopez, Susan K. Lutgendorf, and Anil K. Sood. Nat. Commun. 4:1403 DOI: 10.1038/ncomms2413 (2013)
Integrated Analyses Identify a Master MicroRNA Regulatory Network for the Mesenchymal Subtype in Serous Ovarian Cancer. Da Yang, Yan Sun, Limei Hu, Hong Zheng, Ping Ji, Chad V. Pecot, Yanrui Zhao, Sheila Reynolds, Hanyin Cheng, Rajesha Rupaimoole, David Cogdell, Matti Nykter, Russell Broaddus, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Jinsong Liu, Ilya Shmulevich, Anil K. Sood, Kexin Chen, and Wei Zhang. Cancer Cell 23, 186–199, 2013.
Association of A microRNA/TP53 Feedback Circuitry with the Pathogenesis and Prognostic Factors of B-Chronic Lymphocytic Leukemia. Muller Fabbri, Arianna Bottoni, Masayoshi Shimizu, Riccardo Spizzo, Milena S. Nicoloso, Simona Rossi, Elisa Barbarotto, Amelia Cimmino, Brett Adair, Sylwia E. Wojcik, Nicola Valeri, Federica Calore, Deepa Sampath, Francesca Fanini, Ivan Vannini, Gerardo Musuraca, Marie Dell’Aquila, Hansjuerg Alder, Ramana V. Davuluri, Laura Z. Rassenti, Massimo Negrini, Tatsuya Nakamura, Dino Amadori, Neil E. Kay, Kanti R. Rai, Michael J. Keating, Thomas J. Kipps, George A. Calin, and Carlo M. Croce. JAMA, 2011 Jan 5;305(1):59-67. PMID: 21205967
miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts. Anna M. Eiring, Jason G. Harb, Paolo Neviani, Christopher Garton, Joshua J. Oaks, Riccardo Spizzo, Shujun Liu, Sebastian Schwind, Ramasamy Santhanam, Christopher J. Hickey, Heiko Becker, Jason C. Chandler, Raul Andino, Jorge Cortes, Peter Hokland,Claudia S. Huettner, Ravi Bhatia, Denis C. Roy, Stephen A. Liebhaber, Michael A. Caligiuri, Guido Marcucci, Ramiro Garzon, Carlo M. Croce, George A. Calin, and Danilo Perrotti. Cell 140, 652–665, 2010. PMID: 20211135
Regulation of Tumor Angiogenesis by EZH2. Chunhua Lu, Hee Dong Han, Lingegowda S. Mangala, Rouba Ali-Fehmi, Christopher S. Newton, Laurent Ozbun, Guillermo N. Armaiz-Pena, Wei Hu, Rebecca L. Stone, Adnan Munkarah, Murali K. Ravoori, Mian M.K. Shahzad, Jeong-Won Lee, Edna Mora, Robert R. Langley, Amy R. Carroll, Koji Matsuo, Whitney A. Spannuth, Rosemarie Schmandt, Nicholas B. Jennings, Blake W. Goodman, Robert B. Jaffe, Alpa M. Nick, Hye Sun Kim, Eylem Ozturk Guven, Ya-Huey Chen, Long-Yuan Li, Ming-Chuan Hsu, Robert L. Coleman, George A. Calin, Emir B. Denkbas, Jae Yun Lim, Ju-Seog Lee, Vikas Kundra, Michael J. Birrer, Mien-Chie Hung, Gabriel Lopez-Berestein, and Anil K. Sood. Cancer Cell 18, 185–197, 2010. PMID: 20708159
Single-Nucleotide Polymorphisms inside MicroRNA Target Sites Influence Tumor. Susceptibility. Nicoloso MS, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M, Wojcik SE, Ferdin J, Kunej T, Xiao L, Manoukian S, Secreto G, Ravagnani F, Wang X, Radice P, Croce CM, Davuluri RV, Calin GA. Cancer Research 2010 Apr 1;70(7):2789-98. PMID: 20332227
Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles. Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman P. Mann, Edna Mora, Hee-Dong Han, Mian M.K. Shahzad, Xuewu Liu, Rohan Bhavane, Jianhua Gu, Jean R. Fakhoury, Ciro Chiappini, Chunhua Lu, Koji Matsuo, Biana Godin, Rebecca L. Stone, Alpa M. Nick, Gabriel Lopez-Berestein, Anil K. Sood, and Mauro Ferrari. Cancer Research May 1, 2010.70(9):3687-3696. PMID: 20430760
SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer. Ahmed Ashour Ahmed, Zhen Lu, Nicholas B. Jennings, Dariush Etemadmoghadam, Luisa Capalbo, Rodrigo O. Jacamo, Nuno Barbosa-Morais, Xiao-Feng Le, Australian Ovarian Cancer Study Group, Pablo Vivas-Mejia, Gabriel Lopez-Berestein, Geoffrey Grandjean, Geoffrey Bartholomeusz, Warren Liao, Michael Andreeff, David Bowtell, David M. Glover, Anil K. Sood, and Robert C. Bast, Jr. Cancer Cell 18, 109–121, August 17, 2010. PMID: 20708153
The Meaning of 21 in the MicroRNA World: Perfection Rather than Destruction? Eun-Jung Jung and George A. Calin. Cancer Cell 18, 203-205, 2010. PMID: 20832748
The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cell of the tumor microenvironment. Ramachandran V, Arumugam T, Langley R, Hwang RF, Vivas-Mejia P, Sood AK, Lopez-Berestein G, Logsdon CD. PLoS One. 2009 Oct 22:4(10):e7502; 1-12. PMID: 19847298
Names in bold font represents MD Anderson Cancer Center RNA Center personnel (current and past).