Publications
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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
Read article in Molecular Cell Opens a new window
Mao C, Lei G, Horbath A, Wang M, Lu Z, Yan Y, Liu X, Kondiparthi L, Chen X, Cheng J, Li Q, Xu Z, Zhuang L, Fang B, Marszalek J, Poyurovsky M, Olszewski K, Gan B. 2024 May 16; 84(10):1964-1979
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IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis
Read article in Nature Communications Opens a new window
Jiang D, Guo Y, Wang T, Wang L, Yan Y, Xia L, Bam R, Yang Z, Lee H, Iwawaki T, Gan B, Koong A. 2024 May 15;15(1):4114
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VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas
Read article in Journal of Clinical Investigation Opens a new window
Lee H, Zhuang L, Gan B. 2024 Apr 15; 134(8): e179560
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The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions
Read article in Cancer Cell Opens a new window
Lei G, Zhuang L, Gan B. 2024 Apr 8;42(4):513-534
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Disulfidptosis: disulfide stress-induced cell death
Read article in Trends Cell Biology Opens a new window
Liu X, Zhuang L, Gan B. 2024 Apr;34(4):327-337
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Exploring Ferroptosis-Inducing Therapies for Cancer Treatment: Challenges and Opportunities
Read article in Cancer Research Opens a new window
Lei G, Gan B. 2024 Apr 1;84(7):961-964
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BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers
Read article in Cancer Discovery Opens a new window
Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B. 2024 Mar 28
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SLC25A39 links mitochondrial GSH sensing with iron metabolism
Read article in Molecular Cell Opens a new window
Chen X, Gan B. 2024 Feb 15;84(4):616-618
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Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
Read article in Nature Communications Opens a new window
Lee H, Horbath A, Kondiparthi L, Meena JK, Lei G, Dasgupta S, Liu X, Zhuang L, Koppula P, Li M, Mahmud I, Wei B, Lorenzi PL, Keyomarsi K, Poyurovsky MV, Olszewski K, Gan B. 2024 Jan 2;15(1):79
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The pyrimidinosome: Orchestrating pyrimidine biosynthesis and ferroptosis defense
Read article in Molecular Cell Opens a new window
Gan B. 2023 Aug 17; 83 (16) 2837-2839
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Uncovering the IL-1β-PCAF-NNT axis: A new player in ferroptosis and tumor immune evasion
Read article in Cancer Communications Opens a new window
Li Q, Gan B. 2023 Jul 24
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Ferroptosis vulnerability in FLT3-mutant leukemia
Read article in Trends in Cancer Opens a new window
Lee H, Zhuang L, Gan B. 2023 Jul; 9 (7) 524-525
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SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells
Read article in Nature Communications Opens a new window
Yan Y, Teng H, Hang Q, Kondiparthi L, Lei G, Horbath A, Liu X, Mao C, Wu S, Zhuang L, James M, Poyurovsky M, Ma L, Olszewski K, Gan B. 2023 Jun 21; 14 (1) 3673
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Ferroptosis hijacking by Mycobacterium tuberculosis
Read article in Nature Communications Opens a new window
Gan B. 2023 Mar 17; 14 (1) 1431
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A Time and Place for Inhibiting Autophagy
Read article in Cancer Research Opens a new window
Gan B. 2022 Dec 02; 82 (23) 4322-4324