Lab Members
Han Xu, Ph.D.
Principal Investigator
Associate Professor
B.S. and M.S. in Computer Science, Zhejiang University, China
Ph.D. in Bioinformatics, Nanyang Technological University, Singapore
Email: hxu4@mdanderson.org
Research Interests: bioinformatics and computational biology, transcriptional and epigenetic regulation
Rongjie Fu, Ph.D.
Postdoctoral Fellow
B.S. in Biotechnology, Northwest A&F University, China
Ph.D. in Biochemistry and Molecular Biology, Institute of Health Sciences, University of Chinese Academy of Sciences, China
Email: rfu1@mdanderson.org
Research Interests: Drug resistance in cancer targeted therapy and immunotherapy
Current Research: The molecular mechanism of CRISPR/Cas9 off-target effect; identification of driver factors in cancer drug resistance using CRISPR screens
Wei He, Ph.D.
Postdoctoral Fellow
B.S. in Biology, The Nanjing University of Science and Technology, China
Ph.D. in Bioinformatics, The University of Science and Technology of China, China
Email: whe3@mdanderson.org
Research Interest: Methodology development for high-throughput biomedical and multi-omics data analysis
Current Research: Computational modeling and prediction of CRISPR/Cas9 on-target efficacy and off-target effects; computational approaches for understanding transcriptional and epigenetic regulatory networks
Weijun Liu, Ph.D.
Research Scientist
B.S. in Clinical Medicine, Suzhou Medical College, China
Ph.D. in Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China
Email: wliu14@mdanderson.org
Research Interest: Applications of CRISPR/Cas9-related techniques
Current Research: Whole genome screening using CRISPR/Cas9 to explore mechanisms of protein arginine methyltransferase inhibitor resistance in cancer cells
Shuyue Wang
Graduate Student
B.S. in Bio-pharmaceutics, Shanghai Ocean University, China
M.S. in Pharmaceutical Sciences, Northeastern University, MA
Email: swang21@mdanderson.org
Research Interests: Integration of multi-omics data to highlight biomedical interrelationships and functions
Current Research: Inference of transcriptional regulatory networks from single cell CRISPR perturbation data
Former Lab Members
Liang (Leon) Zhang, Ph.D.
Postdoctoral Fellow
Research Interests: Molecular mechanisms of genes in cancer development and cancer therapy; using CRISPR screens to identify synthetic lethality of epigenetic regulators in cancer cells; high-throughput approaches for characterization of functional domains in transcription factors and epigenetic regulators