Research

Radiologic Pathologic Correlation of Advanced MR imaging to Guide the Biopsy of Cerebral Malignancies 
Schellingerhout (PI)                      01/01/2011 – 12/31/2016
MD Anderson Diagnostic Imaging Clinical Research Committee Funds
This study uses advanced MR imaging to improve under-grading bias in biopsies of primary brain tumors and obtain precise localization for imaging biomarkers to pathology/proteomic/metabolomics/genomic correlation.

Radiologic Pathologic Correlation of Advanced MR imaging to Guide the Biopsy of Cerebral Malignancies
Schellingerhout (PI)                      01/01/2012 – 12/31/2016
MD Anderson Clinical Research Finance Molecular Evaluation and Biopsy Funds
This study pays for clinical costs related to a physician-initiated clinical trial (the Stereotactic RadPath trial) to improve under-grading bias in biopsies of primary brain tumors and obtain precise localization for imaging biomarkers to pathology/proteomic/metabolomics/genomic correlation.

Radiologic-Pathologic Correlation on Stereotactic Biopsies in Glioma Patients
Schellingerhout (PI)                      02/01/2015 – 01/31/2017
MD Anderson Cancer Center - Institutional Research Grant
The purpose of this project is to fund pathologic analysis of samples harvested in the Stereotactic RadPath trial.

A New Treatment for Brain Tumors: Targeting Tumor Metabolism with Glucose-based Therapeutic Agents and Monitoring Treatment Response with Hyperpolarized MR-Spectroscopy
Schellingerhout (PI)                      11/01/2015 – 10/31/2016
Rose Foundation
The goal of this project is to use Hyperpolarized Pyruvate imaging to assess the metabolic effects of anti-glycolytic therapies in glioma.

Predicting Radiation-Induced Cord Myelopathy Using a Molecular Imaging Readout of Retrograde Axonal Transport to Predict Myelopathy
Schellingerhout/Court/Ghia (PIs)           01/01/2016 – 12/31/2016
MDACC Center for Radiation Oncology Research Seed Funding Program
The purpose of this project is to investigate the ability of molecular imaging, used as a readout of retrograde axonal transport, to predict myelopathic radiation injury to the spinal cord.
Role: Co-Principal Investigator
 

Hemorrhagic versus Calcific Brain Lesion Study
Schellingerhout (PI)                      08/01/2015 – 05/01/2018
CABI GE Healthcare Award
The purpose of this project is to use Dual Energy CT and Phase Sensitive MR in a clinical trial to characterize brain lesions, and allow high-risk hemorrhagic lesions to be better discriminated from low-risk calcific lesions.