Yuan Pan Laboratory

Welcome to the Pan Laboratory, in MD Anderson's Department of Symptom Research. Our group studies neuron-cancer and neuron-glia crosstalk and how these interactions are influenced by modifiers such as genetic mutations and therapies. Our goal is to provide insights into the prediction, prevention and treatment of nervous system cancer and neurological disorders. We leverage primary cell culture, genetically engineered mouse models, patient-derived xenograft models, neuromodulatory approaches, and cell and molecular biology approaches. Our research is supported by the Cancer Prevention and Research Institute of Texas (CPRIT), the Department of Defense Neurofibromatosis Research Program, The University of Texas System, the Gilbert Family Foundation and Alex’s Lemonade Stand Foundation.