Publications

Kim ST, Bittar M, Kim HJ, Neelapu SS, Zurita AJ, Nurieva R, Suarez-Almazor ME. Recurrent pseudogout after therapy with immune checkpoint inhibitors: a case report with immunoprofiling of synovial fluid at each flare. J Immunother Cancer.2019 May 14;7(1):126. doi: 10.1186/s40425-019-0597-x. PubMed PMID: 31088575; PubMed Central PMCID: PMC6518723.

Liu X, Wang Y, Lu H, Li J, Yan X, Xiao M, Hao J, Alekseev A, Khong H, Chen T, Huang R, Wu J, Zhao Q, Wu Q, Xu S, Wang X, Jin W, Yu S, Wang Y, Wei L, Wang A, Zhong B, Ni L, Liu X, Nurieva R, Ye L, Tian Q, Bian XW, Dong C. Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction. Nature. 2019 Mar;567(7749):525-529. doi: 10.1038/s41586-019-0979-8. Epub 2019 Feb 27. PubMed PMID: 30814730; PubMed Central PMCID: PMC6507425.

Qin L, Waseem TC, Sahoo A, Bieerkehazhi S, Zhou H, Galkina EV, Nurieva R. Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology. Front Immunol. 2018;9:1884. doi: 10.3389/fimmu.2018.01884. eCollection 2018. Review. PubMed PMID: 30158933; PubMed Central PMCID: PMC6104131.

Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ. IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res. 2018 Jul;6(7):788-797. doi: 10.1158/2326-6066.CIR-17-0655. Epub 2018 May

Haymaker CL, Hailemichael Y, Yang Y, Nurieva R. In Vivo Assay for Detection of Antigen-specific T-cell Cytolytic Function Using a Vaccination Model. J Vis Exp. 2017 Nov 28;(129). doi: 10.3791/56255. PubMed PMID: 29286361; PubMed Central PMCID: PMC5755481.

Haymaker C, Yang Y, Wang J, Zou Q, Sahoo A, Alekseev A, Singh D, Ritthipichai K, Hailemichael Y, Hoang ON, Qin H, Schluns KS, Wang T, Overwijk WW, Sun SC, Bernatchez C, Kwak LW, Neelapu SS, Nurieva R. Absence of Grail promotes CD8⁺ T cell anti-tumour activity. Nat Commun. 2017 Aug 10;8(1):239. doi: 10.1038/s41467-017-00252-w. PubMed PMID: 28798332; PubMed Central PMCID: PMC5552797.

Wali S, Sahoo A, Puri S, Alekseev A, Nurieva R. Insights into the development and regulation of T follicular helper cells.Cytokine. 2016 Nov;87:9-19. doi: 10.1016/j.cyto.2016.06.010. Epub 2016 Jun 20. Review. PubMed PMID: 27339151; PubMed Central PMCID: PMC5108526.

Sahoo A, Wali S, Nurieva R. T helper 2 and T follicular helper cells: Regulation and function of interleukin-4. Cytokine Growth Factor Rev. 2016 Aug;30:29-37. doi: 10.1016/j.cytogfr.2016.03.011. Epub 2016 Mar 31. Review. PubMed PMID: 27072069; PubMed Central PMCID: PMC5110032.

Sahoo A, Alekseev A, Tanaka K, Obertas L, Lerman B, Haymaker C, Clise-Dwyer K, McMurray JS, Nurieva R. Batf is important for IL-4 expression in T follicular helper cells. Nat Commun. 2015 Aug 17;6:7997. doi: 10.1038/ncomms8997. PubMed PMID: 26278622; PubMed Central PMCID: PMC4557271.

Sahoo A, Alekseev A, Obertas L, Nurieva R. Grail controls Th2 cell development by targeting STAT6 for degradation. Nat Commun. 2014 Aug 22;5:4732. doi: 10.1038/ncomms5732. PubMed PMID: 25145352; PubMed Central PMCID: PMC5100808.

Nurieva R, Wang J, Sahoo A. T-cell tolerance in cancer. Immunotherapy. 2013 May;5(5):513-531. doi: 10.2217/imt.13.33. Review. PubMed PMID: 23638746; PubMed Central PMCID: PMC5103631.

Nurieva RI, Podd A, Chen Y, Alekseev AM, Yu M, Qi X, Huang H, Wen R, Wang J, Li HS, Watowich SS, Qi H, Dong C, Wang D.STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem. 2012 Mar 30;287(14):11234-9. doi: 10.1074/jbc.M111.324046. Epub 2012 Feb 8. PubMed PMID: 22318729; PubMed Central PMCID: PMC3322890.

Nurieva RI, Liu X, Dong C. Molecular mechanisms of T-cell tolerance. Immunol Rev. 2011 May;241(1):133-44. doi: 10.1111/j.1600-065X.2011.01012.x. Review. PubMed PMID: 21488895; PubMed Central PMCID: PMC5131796.

Nurieva RI, Zheng S, Jin W, Chung Y, Zhang Y, Martinez GJ, Reynolds JM, Wang SL, Lin X, Sun SC, Lozano G, Dong C. The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity. 2010 May 28;32(5):670-80. doi: 10.1016/j.immuni.2010.05.002. Epub 2010 May 20. PubMed PMID: 20493730; PubMed Central PMCID: PMC2915546.

Nurieva RI, Chung Y. Understanding the development and function of T follicular helper cells. Cell Mol Immunol. 2010 May;7(3):190-7. doi: 10.1038/cmi.2010.24. Epub 2010 Apr 12. Review. PubMed PMID: 20383172; PubMed Central PMCID: PMC4002918.

Nurieva RI, Dong C. (IL-)12 and 21: a new kind of help in the follicles. Immunol Cell Biol. 2009 Nov-Dec;87(8):577-8. doi: 10.1038/icb.2009.79. PubMed PMID: 19907426.

Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, Matskevitch TD, Wang YH, Dong C. Bcl6 mediates the development of T follicular helper cells. Science. 2009 Aug 21;325(5943):1001-5. doi: 10.1126/science.1176676. Epub 2009 Jul 23. PubMed PMID: 19628815; PubMed Central PMCID: PMC2857334.

Nurieva RI, Liu X, Dong C. Yin-Yang of costimulation: crucial controls of immune tolerance and function. Immunol Rev.2009 May;229(1):88-100. doi: 10.1111/j.1600-065X.2009.00769.x. Review. PubMed PMID: 19426216; PubMed Central PMCID: PMC2875245.

Nurieva R, Yang XO, Chung Y, Dong C. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol. 2009 Mar 1;182(5):2565-8. doi: 10.4049/jimmunol.0803931. PubMed PMID: 19234148; PubMed Central PMCID: PMC2755098.

Nurieva RI, Dong C. Keeping autoimmunity in check: how to control a Th17 cell controller. Immunity. 2008 Dec 19;29(6):841-3. doi: 10.1016/j.immuni.2008.12.001. PubMed PMID: 19100696.

Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang YH, Watowich SS, Jetten AM, Tian Q, Dong C. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity.2008 Jul 18;29(1):138-49. doi: 10.1016/j.immuni.2008.05.009. Epub 2008 Jul 3. PubMed PMID: 18599325; PubMed Central PMCID: PMC2556461.

Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C.Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature. 2007 Jul 26;448(7152):480-3. doi: 10.1038/nature05969. Epub 2007 Jun 20. PubMed PMID: 17581589.

Nurieva RI, Chuvpilo S, Wieder ED, Elkon KB, Locksley R, Serfling E, Dong C. A costimulation-initiated signaling pathway regulates NFATc1 transcription in T lymphocytes. J Immunol. 2007 Jul 15;179(2):1096-103. doi: 10.4049/jimmunol.179.2.1096. PubMed PMID: 17617602.

Nurieva RI. Regulation of immune and autoimmune responses by ICOS-B7h interaction. Clin Immunol. 2005 Apr;115(1):19-25. doi: 10.1016/j.clim.2005.02.010. Review. PubMed PMID: 15870016.

Dong C, Nurieva RI. Regulation of immune and autoimmune responses by ICOS. J Autoimmun. 2003 Nov;21(3):255-60. PubMed PMID: 14599850.

Nurieva RI, Duong J, Kishikawa H, Dianzani U, Rojo JM, Ho Ic, Flavell RA, Dong C. Transcriptional regulation of th2 differentiation by inducible costimulator. Immunity. 2003 Jun;18(6):801-11. PubMed PMID: 12818161.

Nurieva RI, Treuting P, Duong J, Flavell RA, Dong C. Inducible costimulator is essential for collagen-induced arthritis. J Clin Invest. 2003 Mar;111(5):701-6. doi: 10.1172/JCI17321. PubMed PMID: 12618524; PubMed Central PMCID: PMC151904.