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Recent Publications

2024 Publications

Albuquerque J, Lin YM, Paolucci I, O'Connor CS, Tzeng CW, Vauthey JN, Brock KK, Odisio BC. Incidental ring-hyperenhancing liver micronodules at CT hepatic arteriography-guided percutaneous thermal ablation of colorectal liver metastases. Radiol Imaging Cancer. 6(2):e230099, 03/2024. PMID: 38363196; PMCID: PMC10988328.
Lin YM, Paolucci I, Albuquerque Marques Silva J, O'Connor CS, Hong J, Shah KY, Abdelsalam ME, Habibollahi P, Jones KA, Brock KK, Odisio BC. Ablative margin quantification using deformable versus rigid image registration in colorectal liver metastasis thermal ablation: a retrospective single-center study. Eur Radiol. Epub 02/2024 – available online ahead of print. PMID: 38334762.
Gupta AC, Cazoulat G, Al Taie M, Yedururi S, Rigaud B, Castelo A, Wood J, Yu C, O'Connor C, Salem U, Silva JAM, Jones AK, McCulloch M, Odisio BC, Koay EJ, Brock KK. Fully automated deep learning-based auto-contouring of liver segments and spleen on contrast-enhanced CT images. Sci Rep. 14(1):4678, 02/2024. PMID: 38409252; PMCID: PMC10967337.
Patel N, Celaya A, Eltaher M, Glenn R, Savannah KB, Brock K, Sanchez J, Calderone T, Cleere D, Elsaiey A, Cagley M, Gupta N, Victor D, Beretta L, Koay E, Netherton T, Fuentes D. Training Robust T1-Weighted Magnetic Resonance Imaging Liver Segmentation Models Using Ensembles of Datasets with Different Contrast Protocols and Liver Disease Etiologies. Sci Rep. 14(1):20988, 09/2024. PMID: 39251644; PMCID:11385384. (Preprint published in Res Seq: 04/2024. PMID: 38746406, PMCID: PMC11092841)
Heshmat A, O'Connor CS, Albuquerque Marques Silva J, Paolucci I, Jones AK, Odisio BC, Brock KK. Using Patient-Specific 3D Modeling and Simulations to Optimize Microwave Ablation Therapy for Liver Cancer. Cancers (Basel). 16(11):2095, 05/2024. PMID: 38893214.
Sheth RA, Wehrenberg-Klee E, Patel SP, Brock KK, Fotiadis N, de Baère T. Intratumoral Injection of Immunotherapeutics: State of the Art and Future Directions. Radiology. 312(1):e232654, 07/2024. PMID: 39078294.
Whelan BM, Brock KK, Li Z. Software from publicly funded research should be free and open source for research. Med Phys. 51(7):4550-4553, 07/2024. Epub 05/2024. PMID:38703398.
Hurkmans C, Bibault JE, Brock KK, van Elmpt W, Feng M, David Fuller C, Jereczek-Fossa BA, Korreman S, Landry G, Madesta F, Mayo C, McWilliam A, Moura F, Muren LP, El Naqa I, Seuntjens J, Valentini V, Velec M. A joint ESTRO and AAPM guideline for development, clinical validation and reporting of artificial intelligence models in radiation therapy. Radiother Oncol. 197:110345, 08/2024. Epub 06/2024. PMID: 38838989.
Paolucci I, Albuquerque Marques Silva J, Lin YM, Laimer G, Cignini V, Menchini F, Meira M, Shieh A, O'Connor C, Jones KA, Gazzera C, Fonio P, Brock KK, Calandri M, Menezes M, Bale R, Odisio BC. Identification of A0 minimum ablative margins for colorectal liver metastases: multicentre, retrospective study using deformable CT registration and artificial intelligence-based autosegmentation. Br J Surg. 111(9):znae165, 08/2024. PMID: 39213397; PMCID: PMC11364140.
Lin YM, Paolucci I, Albuquerque Marques Silva J, O'Connor CS, Hong J, Shah KY, Abdelsalam ME, Habibollahi P, Jones KA, Brock KK, Odisio BC. Ablative margin quantification using deformable versus rigid image registration in colorectal liver metastasis thermal ablation: a retrospective single-center study. Eur Radiol. 34(9):5541-5550, 09/2024. Epub 02/2024. PMID: 38334762.
MD Anderson Head and Neck Symptom Working Group, Humbert-Vidan L, Kamel S, Wentzel A, Kaffey Z, Abdelaal M, Spier KB, West NA, Elisabeta Marai G, Canahuate G, Zhang X, Chen MM, Wahid KA, Rigert J, Hosseinian S, Schaefer AJ, Brock KK, Chambers M, Otun AO, Aponte-Wesson R, Patel V, Hope A, Phan J, Garden AS, Frank SJ, Morrison WH, Spiotto MT, Rosenthal D, Lee A, He R, Naser MA, Watson E, Hutcheson KA, Mohamed, ASR, Sandaluche VC, van Dijk LV, Moreno AC, Guerrero Urbano T, Lai SY, Fuller CD. Mandibular dose-volume predicts time-to-osteoradionecrosis in an actuarial normal-tissue complication probability (NTCP) model: External validation of right-censored clinico-dosimetric and competing risk application across international multi-institutional observational cohorts and online graphical user interface clinical support tool assessment. medRxiv, 2024.08.20.24312311, 08/2024. PMID: 39228724; PMCID: PMC11370531. Preprint.
MD Anderson Head and Neck Cancer Symptom Working Group; Kamel S, Humbert-Vidan L, Kaffey Z, Abusaif A, Fuentes DTA, Wahid K, Dede C, Naser MA, He R, Moawad AW, Elsayes KM, Chen MM, Otun AO, Rigert J, Chambers M, Hope A, Watson E, Brock KK, Hutcheson K, van Dijk L, Moreno AC, Lai SY, Fuller CD, Mohamed ASR. Computed tomography radiomics-based cross-sectional detection of mandibular osteoradionecrosis in head and neck cancer survivors. medRxiv. 2024.09.11.24313485, 09/2024. PMID: 39314948; PMCID: PMC11419222. Preprint.

2023 Publications

Lin YM, Paolucci I, O'Connor CS, Anderson BM, Rigaud B, Fellman BM, Jones KA, Brock KK, Odisio BC. Ablative margins of colorectal liver metastases using deformable CT image registration and autosegmentation. Radiology; 307(2): e221373, 04/2023. e-Pub 01/2023. PMID: 36719291, PMCID: PMC1012669.
Paolucci I, Lin YM, Jones AK, Brock KK, Odisio BC. Use of contrast media during CT-guided thermal ablation of colorectal liver metastasis for procedure planning is associated with improved immediate outcomes. Cardiovasc Intervent Radiol.; 46(3):327-336, 03/2023. e-Pub 01/2023. PMID: 36609863, PMCID: PMC10446157.
Murr M, Brock KK, Fusella M, Hardcastle N, Hussein M, Jameson MG, Wahlstedt I, Yuen J, McClelland JR, Vasquez Osorio E. Applicability and usage of dose mapping/accumulation in radiotherapy. Radiother Oncol; 182:109527, 05/2023. e-Pub 02/2023. PMID: 36773825.
Baroudi H, Brock KK, Cao W, Chen X, Chung C, Court LE, El Basha MD, Farhat M, Gay S, Gronberg MP, Gupta AC, Hernandez S, Huang K, Jaffray DA, Lim R, Marquez B, Nealon K, Netherton TJ, Nguyen CM, Reber B, Rhee DJ, Salazar RM, Shanker MD, Sjogreen C, Woodland M, Yang J, Yu C, Zhao Y. Automated contouring and planning in radiation therapy: What is 'clinically acceptable'? Diagnostics (Basel).; 13(4):667, 02/2023. PMID: 36832155, PMCID: PMC9955359.
Brock, KK, Chen SR, Sheth RA, Siewerdsen JH. Imaging in interventional radiology: 2043 and beyond. Radiology; 308(1):e230146. 07/2023. Epub 01/2023. PMID: 37462500, PMCID: PMC10374939.
Moreno A, Solanki AA, Xu T, Lin R, Palta J, Daugherty E, Hong D, Hong J, Kamran SC, Katsoulakis E, Brock K, Feng M, Fuller C, Mayo C; BDSC Prostate Cancer Consortium. Identification of key elements in prostate cancer for ontology building via a multidisciplinary consensus agreement. Cancers (Basel); 15(12):3121. 06/2023. PMID: 37370731, PMCID: PMC10295832.
Jeun R, Iyer PC, Best C, Lavis V, Varghese JM, Yedururi S, Brady V, Glitza Oliva IC, Dadu R, Milton DR, Brock K, Thosani S. Clinical outcomes of immune checkpoint inhibitor diabetes mellitus at a comprehensive cancer center. Immunotherapy; 15(6):417-428, 04/2023. e-Pub 04/2023. PMID: 37013834. PMCID: PMC10088048.
McDonald BA, Cardenas CE, O'Connell N, Ahmed S, Naser MA, Wahid KA, Xu J, Thill D, Zuhour RJ, Mesko S, Augustyn A, Buszek SM, Grant S, Chapman BV, Bagley AF, He R, Mohamed ASR, Christodouleas J, Brock KK, Fuller CD. Investigation of autosegmentation techniques on T2-weighted MRI for off-line dose reconstruction in MR-linac workflow for head and neck cancers. Med Phys; 51(1):278-291, 01/2024. e-Pub 07/2023. PMID: 37475466, PMCID: PMC10799175.
He Y, Cazoulat G, Wu C, Svensson S, Almodovar-Abreu L, Rigaud B, McCollum E, Peterson C, Wooten Z, Rhee DJ, Balter P, Pollard-Larkin J, Cardenas C, Court L, Liao Z, Mohan R, Brock K. Quantifying the effect of 4-dimensional computed tomography-based deformable dose accumulation on representing radiation damage for patients with locally advanced non-small cell lung cancer treated with standard-fractionated intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys; 118(1):2310241, 01/2024. e-Pub 08/2023. PMID: 37552151.
Paolucci I, Albuquerque Marques Silva J, Lin YM, Fellman BM, Jones KA, Tatsui CE, Weinberg JS, Ruiz J, Tan J, Brock KK, Bale R, Odisio BC. Study Protocol STEREOLAB: Stereotactic Liver Ablation Assisted with Intra-Arterial CT Hepatic Arteriography and Ablation Confirmation Software Assessment. Cardiovasc Intervent Radiol.; 46(12):1748-1754, 12/2023. e-Pub 08/2023. PMID: 37563313.
Noh S, Bertini C, Mira-Avendano I, Kaous M, Patel B, Faiz SA, Shannon VR, Balachandran DD, Bashoura L, Adachi R, Evans SE, Dickey B, Wu C, Shroff GS, Manzano JG, Granwehr B, Holloway S, Dickson K, Mohammed A, Muthu M, Song H; D3CODE Team; Chung C, Wu J, Lee L, Jiang Y, Khawaja F, Sheshadri A. Interstitial lung abnormalities after hospitalization for COVID-19 in patients with cancer: A prospective cohort study. Cancer Med.; 12(17):17753-17765, 09/2023. e-Pub 08/2023. PMID: 37592894, PMCID: PMC10524033.
Gay SS, Kisling KD, Anderson BM, Zhang L, Rhee DJ, Nguyen C, Netherton T, Yang J, Brock K, Jhingran A, Simonds H, Klopp A, Beadle BM, Court LE, Cardenas CE. Identifying the optimal deep learning architecture and parameters for automatic beam aperture definition in 3D radiotherapy. J Appl Clin Med Phys.; 24(12):e14131, 12/2023. e-Pub 09/2023. PMID: 37670488, PMCID: PMC10691634.
Cazoulat G, Gupta AC, Al Taie MM, Koay EJ, Brock KK. Analysis and prediction of liver volume change maps derived from computational tomography scans acquired pre- and post-radiation therapy. Phys Med Biol.; 68(20):205009, 10/2023. PMID: 37714187, PMCID: PMC10547850.
Paolucci I, Lin YM, Albuquerque Marques Silva J, Brock KK, Odisio BC. Bayesian parametric models for survival prediction in medical applications. BMC Med Res Metholol.; 23(1):250, 10/2023. PMID:37884857, PMCID: PMC10605790.
Lin YM, Paolucci I, Albuquerque Marques Silva J, O'Connor CS, Fellman BM, Jones AK, Kuban JD, Huang SY, Metwalli ZA, Brock KK, Odisio BC. Intraprocedural versus initial follow-up minimal ablative margin assessment after colorectal liver metastasis thermal ablation: Which one better predicts local outcomes? Invest Radiol.; 59(4): 314-319, 04/2024. e-Pub 10/2023. PMID: 37812469.
Jacobsen MC, Rigaud B, Simiele SJ, Rauch GM, Ning MS, Vedam S, Klopp AH, Stafford RJ, Brock KK, Venkatesan AM. Feasibility of quantitative diffusion-weighted imaging during intra-procedural MRI-guided brachytherapy of locally advanced cervical and vaginal cancers. Brachytherapy; 22(6):736-745, 11/2023. e-Pub 08/2023. PMID: 37612174.
Mayo CS, Feng MU, Brock KK, Kudner R, Balter P, Buchsbaum JC, Caissie A, Covington E, Daugherty EC, Dekker AL, Fuller CD, Hallstrom AL, Hong DS, Hong JC, Kamran SC, Katsoulakis E, Kildea J, Krauze AV, Kruse JJ, McNutt T, Mierzwa M, Moreno A, Palta JR, Popple R, Purdie TG, Richardson S, Sharp GC, Satomi S, Tarbox LR, Venkatesan AM, Witztum A, Woods KE, Yao Y, Farahani K, Aneja S, Gabriel PE, Hadjiiski L, Ruan D, Siewerdsen JH, Bratt S, Casagni M, Chen S, Christodouleas JC, DiDonato A, Hayman J, Kapoor R, Kravitz S, Sebastian S, Von Siebenthal M, Bosch W, Hurkmans C, Yom SS, Xiao Y. Operational Ontology for Oncology (O3): A professional society-based, multistakeholder, consensus-driven informatics standard supporting clinical and research use of real-world data from patients treated for cancer. Int J Radiat Oncol Biol Phys.; 117(3):533-550, 11/2023. e-Pub 05/2023. PMID: 37244628, PMCID: PMC10741247.

2022 Publications

C Owens, B Rigaud, E Ludmir, A Gupta, S Shrestha, A de la Cruz Paulino, C Peterson, S Kry, S Smith, K Brock, T Henderson, R Howell. Development and validation of a population-based colorectal model for radiation therapy dosimetry. Radiotherapy and Oncology; 176:118-126, 05/2022. e-Pub 09/2022. PMID: 36063983, PMCID: PMC9845018.
Rhee DJ, Akinfenwa CPA, Rigaud B, Jhingran A, Cardenas CE, Zhang L, Prajapati S, Kry SF, Brock KK, Beadle BM, Shaw W, O'Reilly F, Parkes J, Burger H, Fakie N, Trauernicht C, Simonds H, Court LE. Automatic contouring QA method using a deep learning-based autocontouring system. J Appl Clin Med Phys; 23(8):e13647, 08/2022. e-Pub 05/2022. PMID: 35580067, PMCID: PMC9359039.
Rigaud B, Weaver OO, Dennison JB, Awais M, Anderson BM, Chiang TD, Yang WT, Leung JWT, Hanash SM, Brock KK. Deep learning models for automated assessment of breast density using multiple mammographic image types. Cancers (Basel); 14(20):5003, 10/2022. e-Pub 10/2022. PMID: 36291787, PMCID: PMC9599904.
Aminu M, Yadav D, Hong L, Young E, Edelkamp P, Saad M, Salehjahromi M, Chen P, Sujit SJ, Chen MM, Sabloff B, Gladish G, de Groot PM, Godoy MCB, Cascone T, Vokes NI, Zhang J, Brock KK, Daver N, Woodman SE, Tawbi HA, Sheshadri A, Lee JJ, Jaffray D, D3Code Team , Wu CC, Chung C, Wu J. Habitat imaging biomarkers for diagnosis and prognosis in cancer patients infected with COVID-19. Cancers (Basel); 15(1):275, 12/2022. e-Pub 12/2022. PMID: 36612278, PMCID: PMC9818576.
Singh BS, Cazacu IM, Deza CA, Rigaud BS, Saftoiu A, Gruionu G, Guionu L, Brock KK, Koay EJ, Herman JM, Bhutani MS. Image fusion involving real-time transabdominal or endoscopic ultrasound for gastrointestinal malignancies: Review of current and future applications. Diagnostics (Basel); 12(12):3218, 12/2022. e-Pub 12/2022. PMID: 36553225, PMCID: PMC9777678.
Lin YM, Paolucci I, Anderson BM, O'Connor CS, Rigaud B, Briones-Dimayuga M, Jones KA, Brock KK, Fellman BM, Odisio BC. Study protocol COVER-ALL: Clinical impact of a volumetric image method for confirming tumour coverage with ablation on patients with malignant liver lesions. Cardiovasc Intervent Radiol; 45(12):1860-1867, 12/2022. e-Pub 09/2022. PMID: 36058995, PMCID: PMC9712233.
Anderson BM, Rigaud B, Lin YM, Jones AK, Kang HC, Odisio BC, Brock KK. Automated segmentation of colorectal liver metastasis and liver ablation on contrast-enhanced CT images. Front Oncol; 12:886517, 08/2022. e-Pub 08/2022. PMID: 36033508, PMCID: PMC9403767.
Lin YM, Bale R, Brock KK, Odisio BC. Contemporary evidence on colorectal liver metastases ablation: toward a paradigm shift in locoregional treatment. Int J Hyperthermia; 39(1):649-663, 2022. PMID: 35465805.
McDonald BA, Zachiu C, Christodouleas J, Naser MA, Ruschin M, Sonke JJ, Thorwarth D, Létourneau D, Tyagi N, Tadic T, Yang J, Li XA, Bernchou U, Hyer DE, Snyder JE, Bubula-Rehm E, Fuller CD, Brock KK. Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation. Front Oncol; 12:1086258, 2022. e-Pub 01/2023. PMID: 36776378, PMCID: PMC9909539.
McCulloch MM, Cazoulat G, Svensson S, Gryshkevych S, Rigaud B, Anderson BM, Kirimli E, De B, Mathew RT, Zaid M, Elganainy D, Peterson CB, Balter P, Koay EJ, Brock KK. Leveraging deep learning-based segmentation and contours-driven deformable registration for dose accumulation in abdominal structures. Front Oncol; 12:1015608, 11/2022. e-Pub 11/2022. PMID: 364008172, PMCID: PMC9666494.
He Y, Anderson BM, Cazoulat G, Rigaud B, Almodovar-Abreu L, Pollard-Larkin J, Balter P, Liao Z, Mohan R, Odisio B, Svensson S, Brock KK. Optimization of mesh generation for geometric accuracy, robustness, and efficiency of biomechanical-model-based deformable image registration. Med Phys; 50(1):323-329, 01/2023. e-Pub 08/2022. PMID: 35978544.
Paolucci I, Lin YM, Kawaguchi Y, Maki H, Jones AK, Calandri M, Kopetz S, Newhook TE, Brock KK, Vauthey JN, Odisio BC. Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation. Br J Cancer; 128(1):130-136, 01/2023. e-Pub 11/2022. PMID: 36319850, PMCID: PMC9814547.
Reddy DR, Cuenca JA, Botdorf J, Muthu M, Hanmandlu A, Wegner R, Crommett J, Gutierrez C, Rathi N, Sajith B, Knafl M, Abbas HA, Woodman SE, Nates JL, D3CODE Team Collaborators. Clinical characteristics and cause of death among hospitalized decedents with cancer and COVID-19. Mayo Clin Proc; 98(3):451-457, 03/2023. e-Pub 12/2022. PMID: 36868753, PMCID: PMC9794478.
Reber B, Van Dijk L, Anderson B, Mohamed ASR, Fuller C, Lai S, Brock K. Comparison of machine-learning and deep-learning methods for the prediction of osteoradionecrosis resulting from head and neck cancer radiation therapy. Adv Radiat Oncol; 8(4):101163, 07/2023. Epub 12/2022. PMID: 36798732, PMCID: PMC9926206.

2021 Publications

Lee M, Simeonov A, Stanescu T, Dawson LA, Brock KK, Velec M. MRI evaluation of normal tissue deformation and breathing motion under an abdominal compression device. J Appl Clin Med Phys; 22(2):90-97, 02/2021. e-Pub 01/2021. PMID: 33449447, PMCID: PMC7882116.
Anderson BM, Wahid KA, Brock KK. Simple Python module for conversions between DICOM images and radiation therapy structures, masks, and prediction arrays. Pract Radiat Oncol; 11(3):226-229, May-Jun 2021. e-Pub 02/2021. PMID: 33607331, PMCID: PMC33607331.
Thrower SL, Al Feghali KA, Luo D, Paddick I, Hou P, Briere T, Li J, McAleer MF, McGovern SL, Woodhouse KD, Yeboa DN, Brock KK, Chung C. The effect of slice thickness on contours of brain metastases for stereotactic radiosurgery. Adv Radiat Oncol; 6(4):100708, Jul-Aug 2021. e-Pub 04/2021. PMID: 34124413, PMCID: PMC8175282.
He Y, Cazoulat G, Wu C, Peterson C, McCulloch M, Anderson B, Pollard-Larkin J, Balter P, Liao Z, Mohan R, Brock K. Geometric and dosimetric accuracy of deformable image registration between average-intensity images for 4DCT-based adaptive radiotherapy for non-small cell lung cancer. J Appl Clin Med Phys; 22(8):156-167, 08/2021. e-Pub 07/2021. PMID: 34310827, PMCID: PMC8364273.
Lin YM, Paolucci I, Brock KK, Odisio BC. Image-guided ablation for colorectal liver metastasis: Principles, current evidence, and the path forward. Cancers (Basel); 13(16):3926, 08/2021. e-Pub 08/2021. PMID: 34439081, PMCID: PMC8394430.
Sen A, Troncoso P, Venkatesan A, Pagel MD, Nijkamp JA, He Y, Lesage AC, Woodland M, Brock KK. Correlation of in-vivo imaging with histopathology: A review. Eur J Radiol; 144:109964, 11/2021. e-Pub 09/2021. PMID: 34619617.
Anderson BM, Lin YM, Lin EY, Cazoulat G, Gupta S, Kyle Jones A, Odisio BC, Brock KK. A novel use of biomechanical model-based deformable image registration (DIR) for assessing colorectal liver metastases ablation outcomes. Med Phys; 48(10):6226-6236, 10/2021. e-Pub 08/2021. PMID: 34342018, PMCID: PMC9380122.
Cazoulat G, Anderson BM, McCulloch MM, Rigaud B, Koay EJ, Brock KK. Detection of vessel bifurcations in CT scans for automatic objective assessment of deformable image registration accuracy. Med Phys; 48(10):5935-5946, 10/2021. e-Pub 08/2021. PMID: 34390007, PMCID: PMC9132059.
Lesage AC, Simmons A, Sen A, Singh S, Chen M, Cazoulat G, Weinberg JS, Brock KK. Viscoelastic biomechanical models to predict inward brain-shift using public benchmark data. Phys Med Biol; 66(20), 10/2021. e-Pub 10/2021. PMID: 34469879.
Sen A, Fowlkes NW, Kingsley CV, Kulp AM, Huynh T, Willis BJ, Brewer Savannah KJ, Bordes MCA, Hwang KP, McCulloch MM, Stafford RJ, Contreras A, Reece G, Brock KK. Technical note: Histological validation of anatomical imaging for breast modeling using a novel cryo-microtome. Med Phys; 48(11):7323-7332, 11/2021. e-Pub 10/2021. PMID: 34559413.

2020 Publications

Jin Y, Randall JW, Elhalawani H, Feghali KAA, Elliott AM, Anderson BM, Lacerda L, Tran BL, Mohamed AS, Brock KK, Fuller CD, Chung C. Detection of glioblastoma subclinical recurrence using serial diffusion tensor imaging. Cancers (Basel); 12(3):568, 02/2020. e-Pub 02/2020. PMID: 32121471, PMCID: PMC7139975.
Sen A, Anderson BM, Cazoulat G, McCulloch MM, Elganainy D, McDonald BA, He Y, Mohamed ASR, Elgohari BA, Zaid M, Koay EJ, Brock KK. Accuracy of deformable image registration techniques for alignment of longitudinal cholangiocarcinoma CT images. Med Phys; 47(4):1670-1679, 04/2020. e-Pub 02/2020. PMID: 31958147, PMCID: PMC7288249.
Rigaud B, Cazoulat G, Vedam S, Venkatesan AM, Peterson CB, Taku N, Klopp AH, Brock KK. Modeling complex deformations of the sigmoid colon between external beam radiation therapy and brachytherapy images of cervical cancer. Int J Radiat Oncol Biol Phys; 106(5):1084-1094, 04/2020. e-Pub 02/2020. PMID: 32029345.
Parsai S, Qiu RLJ, Qi P, Alfonso JCL, Donaghue J, Murray E, Majkszak D, Dorio N, Fuller CD, Brock K, Koyfman S, Woody N, Joshi N, Scott JG. Technical Note: A step-by-step guide to Temporally Feathered Radiation Therapy planning for head and neck cancer. J Appl Clin Med Phys; 21(7):209-215, 07/2020. e-Pub 05/2020. PMID: 32383296.
McCulloch MM, Cazoulat G, Ford AC, Elgohari B, Bahig H, Kim AD, Elhalawani H, He R, Wang J, Ding Y, Mohamed AS, Polan DF, King JB, Peterson CB, Ohrt AN, Fuller CD, Lai SY, Brock KK. Biomechanical modeling of radiation dose-induced volumetric changes of the parotid glands for deformable image registration. Phys Med Biol; 65(16):165017, 08/2020. e-Pub 08/2020. PMID: 32320955.
Pursley J, El Naqa I, Sanford NN, Noe B, Wo JY, Eyler CE, Hwang M, Brock KK, Yeap BY, Wolfgang JA, Hong TS, Grassberger C. Dosimetric analysis and normal tissue complication probability modeling of Child-Pugh score and Albumin-Bilirubin grade increase after hepatic irradiation. Int J Radiat Oncol Biol Phys; 107(5):986-995, 08/2020. e-Pub 04/2020. PMID: 32353390, PMCID: PMC7381375.
Jacobsen MC, Thrower SL, Ger RB, Leng S, Court LE, Brock KK, Tamm EP, Cressman ENK, Cody DD, Layman RR. Multi-energy computed tomography and material quantification: Current barriers and opportunities for advancement. Med Phys; 47(8):3752-3771, 08/2020. e-Pub 06/2020. PMID: 32453879, PMCID: PMC8495770.
Lesage AJ, Rajaram R, Tam AL, Rigaud BS, Brock KK, Rice DC, Cazoulat G. Preliminary evaluation of biomechanical modeling of lung deflation during minimally invasive surgery using pneumothorax computed tomography scans. Phys Med Biol; 65(22):22510, 11/2020. e-Pub 09/2020. PMID: 32906090.
Rhee DJ, Jhingran A, Rigaud B, Netherton T, Cardenas CE, Zhang L, Vedam S, Kry S, Brock KK, Shaw W, O'Reilly F, Parkes J, Burger H, Fakie N, Trauernicht C, Simonds H, Court LE. Automatic contouring system for cervical cancer using convolutional neural networks. Med Phys; 47(11):5648-5658, 11/2020. e-Pub 10/2020. PMID: 32964477, PMCID: PMC7756586.
Yu JB, Brock KK, Campbell AM, Chen AB, Diaz R, Escorcia FE, Gupta G, Hrinivich WT, Joseph S, Korpics M, Onderdonk BE, Pandit-Taskar N, Wood BJ, Woodward WA. Proceedings of the ASTRO-RSNA Oligometastatic Disease Research Workshop. Int J Radiat Oncol Biol Phys; 108(3):539-545, 11/2020. e-Pub 05/2020. PMID: 32434040.
Anderson BM, Lin EY, Cardenas CE, Gress DA, Erwin WD, Odisio BC, Koay EJ, Brock KK. Automated contouring of contrast and noncontrast computed tomography liver images with fully convolutional networks. Adv Radiat Oncol; 6(1):100464, Jan-Feb 2021. e-Pub 05/2020. PMID: 33490720, PMCID: PMC7807136.
Dominello MM, Sanders T, Anscher M, Bayouth J, Brock KK, Carlson DJ, Hugo G, Joseph S, Knisely J, Mendonca MS, Mian OY, Moros EG, Singh AK, Yu JB. Responses to the 2018 and 2019 "One Big Discovery" question: ASTRO membership's opinions on the most important research question facing radiation oncology…Where are we headed? Int J Radiat Oncol Biol Phys; 109(1):38-40, 01/2021. e-Pub 08/2020. PMID: 32798605.
Cazoulat G, Balter JM, Matuszak MM, Jolly S, Owen D, Brock KK. Mapping lung ventilation through stress maps derived from biomechanical models of the lung. Med Phys; 48(2):715-723, 02/2021. e-Pub 12/2020. PMID: 33617034, PMCID: PMC8444226.
Rigaud B, Anderson BM, Yu ZH, Gobeli M, Cazoulat G, Söderberg J, Samuelsson E, Lidberg D, Ward C, Taku N, Cardenas C, Rhee DJ, Venkatesan AM, Peterson CB, Court L, Svensson S, Löfman F, Klopp AH, Brock KK. Automatic segmentation using deep learning to enable online dose optimization during adaptive radiation therapy of cervical cancer. Int J Radiat Oncol Biol Phys; 109(4):1096-1110, 03/2021. e-Pub 11/2020. PMID: 33181248.

2019 Publications

Yu JB, Beck TF, Anscher MS, Baschnagel AM, Brock KK, Carlson DJ, Dominello MM, Kimple RJ, Knisely JP, Mendonca MS, Mian OY, Singh AK, Moros EG, Keen JC. Analysis of the 2017 American Society for Radiation Oncology (ASTRO) Research Portfolio. Int J Radiat Oncol Biol Phys; 103(2):297-304, 02/2019. PMID: 30647006.
Yu JB, Beck TF, Anscher MS, Baschnagel AM, Brock KK, Carlson DJ, Dominello MM, Kimple RJ, Knisely JPS, Mendonca MS, Mian OY, Singh AK, Moros EG, Keen JC. The ASTRO Research Portfolio: Where do we go from here? Int J Radiat Oncol Biol Phys; 103(2):308-309, 02/2019. PMID: 30647008.
Kipritidis J, Tahir BA, Cazoulat G, Hofman MS, Siva S, Callahan J, Hardcastle N, Yamamoto T, Christensen GE, Reinhardt JM, Kadoya N, Patton TJ, Gerard SE, Duarte I, Archibald-Heeren B, Byrne M, Sims R, Ramsay S, Booth JT, Eslick E, Hegi-Johnson F, Woodruff HC, Ireland RH, Wild JM, Cai J, Bayouth JE, Brock K, Keall PJ. The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging. Med Phys; 46(3):1198-1217, 03/2019. e-Pub 02/2019. PMID: 30575051, PMCID: PMC6605778.
Rigaud B, Klopp A, Vedam S, Venkatesan A, Taku N, Simon A, Haigron P, de Crevoisier R, Brock KK, Cazoulat G. Deformable image registration for dose mapping between external beam radiotherapy and brachytherapy images of cervical cancer. Phys Med Biol; 64(11):115023, 05/2019. e-Pub 05/2019. PMID: 30913542.
Yang Z, Chang Y, Brock KK, Cazoulat G, Koay EJ, Koong AC, Herman JM, Park PC, Poenisch F, Li Q, Yang K, Wu G, Anderson B, Ohrt AN, Li Y, Zhu XR, Zhang X, Li H. Effect of setup and inter-fraction anatomical changes on the accumulated dose in CT-guided breath-hold intensity modulated proton therapy of liver malignancies. Radiother Oncol; 134:101-109, 05/2019. e-Pub 02/2019. PMID: 31005203.
Brock KK. Adaptive radiotherapy: moving into the future. Semin Radiat Oncol; 29(3):181-184, 07/2019. PMID: 31027635, PMCID: PMC7219982.
Cardenas CE, Yang J, Anderson BM, Court LE, Brock KB. Advances in auto-segmentation. Semin Radiat Oncol; 29(3):185-197, 07/2019. PMID: 31027636.
McCulloch MM, Anderson BM, Cazoulat G, Peterson CB, Mohamed ASR, Volpe S, Elhalawani H, Bahig H, Rigaud B, King JB, Ford AC, Fuller CD, Brock KK. Biomechanical modeling of neck flexion for deformable alignment of the salivary glands in head and neck cancer images. Phys Med Biol; 64(17):175018, 09/2019. e-Pub 09/2019. PMID: 31269475, PMCID: PMC7748883.
Joint Head and Neck MRI-Radiotherapy Development Cooperative, Kiser K, Meheissen MAM, Mohamed ASR, Kamal M, Ng SP, Elhalawani H, Jethanandani A, He R, Ding Y, Rostom Y, Hegazy N, Bahig H, Garden A, Lai S, Phan J, Gunn GB, Rosenthal D, Frank S, Brock KK, Wang J, Fuller CD. Prospective quantitative quality assurance and deformation estimation of MRI-CT image registration in simulation of head and neck radiotherapy patients. Clin Transl Radiat Oncol; 18:120-127, 09/2019. e-Pub 04/2019. PMID: 31341987, PMCID: PMC6630195.
Horie M, Levy L, Houbois C, Salazar P, Saito T, Pakkal M, O'Brien C, Sajja S, Brock K, Yasufuku K, Keshavjee S, Paul N, Martinu T. Lung density analysis using quantitative chest CT for early prediction of Chronic Lung Allograft Dysfunction. Transplantation; 103(12):2645-2653, 12/2019. e-Pub 05/2019. PMID: 31343572.
McCulloch MM, Lee C, Rosen BS, Kamp JD, Lockhart CM, Lee JY, Polan DF, Hawkins PG, Anderson CJR, Heukelom J, Sonke JJ, Fuller CD, Balter JM, Ten Haken RK, Eisbruch A, Brock KK. Predictive models to determine clinically relevant deviations in delivered dose for head and neck cancer. Pract Radiat Oncol; 9(4):e422-e431, Jul-Aug 2019. e-Pub 03/2019. PMID: 30836190, PMCID: PMC6592740.
Green CA, Goodsitt MM, Roubidoux MA, Brock KK, Davis CL, Lau JH, Carson PL. Deformable mapping using biomechanical models to relate corresponding lesions in digital breast tomosynthesis and automated breast ultrasound images. Med Image Anal; 60:101599, 02/2020. e-Pub 11/2019. PMID: 31760192.
Green CA, Goodsitt MM, Lau JH, Brock KK, Davis CL, Carson PL. Deformable mapping method to relate lesions in dedicated breast CT images to those in automated breast ultrasound and digital breast tomosynthesis images. Ultrasound Med Biol; 46(3):750-765, 03/2020. e-Pub 12/2019. PMID: 31806500.
Cazoulat G, Elganainy D, Anderson BM, Zaid M, Park PC, Koay EJ, Brock KK. Vasculature-driven biomechanical deformable image registration of longitudinal liver cholangiocarcinoma computed tomographic scans. Adv Radiat Oncol; 5(2):269-278, Mar-Apr 2020. e-Pub 10/2019. PMID: 32280827, PMCID: PMC7136628.

2018 Publications

El Naqa I, Brock KK, Yu Y, Langen K, Klein EE. On the fuzziness of machine learning, neural networks, and artificial intelligence in radiation oncology. Int J Radiat Oncol Biol Phys ;100(1):1-4, 01/2018. PMID: 29254765.
Horie M, Salazar P, Saito T, Binnie M, Brock KK, Yasufuku K, Azad S, Keshavjee S, Martinu T, Paul N. Quantitative chest CT for subtyping chronic lung allograft dysfunction and its association with survival. Clin Transplant.; 32(5):e13233, 05/2018. e-Pub 04/2018. PMID: 29637624.
Mohamed ASR, Bahig H, Aristophanous M, Blanchard P, Kamal M, Ding Y, Cardenas CE, Brock KK, Lai SY, Hutcheson KA, Phan J, Wang J, Ibbott G, Gabr RE, Narayana PA, Garden AS, Rosenthal DI, Gunn GB, Fuller CD, MD Anderson MRLinac Development Working Group. Prospective in silico study of the feasibility and dosimetric advantages of MRI-guided dose adaptation for human papillomavirus positive oropharyngeal cancer patients compared with standard IMRT. Clin Transl Radiat Oncol; 11:11-18, 06/2018. e-Pub 05/2018. PMID: 30014042, PMCID: PMC6019867.
Green CA, Goodsitt MM, Brock KK, Davis CL, Larson ED, Lau JH, Carson PL. Deformable mapping technique to correlate lesions in digital breast tomosynthesis and automated breast ultrasound images. Med Phys; 45(10):4402-4417, 10/2018. e-Pub 08/2018. PMID: 30066340.
Dominello MM, Keen JC, Beck TF, Bayouth J, Knisely J, Carlson DJ, Mendonca MS, Mian O, Brock KK, Anscher M, Hugo G, Moros EG, Singh AK, Yu JB. Responses to the 2017 '1 Million Gray Question': ASTRO membership's opinions on the most important research question facing radiation oncology. Int J Radiat Oncol Biol Phys; 102(2):249-250, 10/2018. e-Pub 07/2018. PMID: 30003995.
Rosen BS, Hawkins PG, Polan DF, Balter JM, Brock KK, Kamp JD, Lockhart CM, Eisbruch A, Mierzwa ML, Ten Haken RK, El Naqa I. Early changes in serial CBCT-measured parotid gland biomarkers predict chronic xerostomia after head and neck radiotherapy. Int J Radiat Oncol Biol Phys; 102(4):1319-1329, 11/2018. e-Pub 07/2018. PMID: 30003997. PMCID: PMC6411287.
Bahig H, Yuan Y, Mohamed ASR, Brock KK, Ng SP, Wang J, Ding Y, Hutcheson K, McCulloch M, Balter PA, Lai SY, Al-Mamgani A, Sonke JJ, van der Heide UA, Nutting C, Li XA, Robbins J, Awan M, Karam I, Newbold K, Harrington K, Oelfke U, Bhide S, Philippens MEP, Terhaard CHJ, McPartlin AJ, Blanchard P, Garden AS, Rosenthal DI, Gunn GB, Phan J, Cazoulat G, Aristophanous M, McSpadden KK, Garcia JA, van den Berg CAT, Raaijmakers CPJ, Kerkmeijer L, Doornaert P, Blinde S, Frank SJ, Fuller CD. Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial. Clin Transl Radiat Oncol; 13:19-23, 11/2018. e-Pub 08/2018. PMID: 30386824, PMCID: PMC6204434.
Brock KK, Yom SS. Seeing what's before us: Imaging in the electronic age. Int J Radiat Oncol Biol Phys; 102(4):675-676, 11/2018. e-Pub 10/2018. PMID: 30353874.
McCulloch MM, Muenz DG, Schipper MJ, Velec M, Dawson LA, Brock KK. A simulation study to assess the potential impact of developing normal tissue complication probability models with accumulated dose. Adv Radiat Oncol; 3(4):662-672, Oct-Dec 2018. e-Pub 05/2018. PMID: 30370368, PMCID: PMC6200914.
Chapman CH, Polan D, Vineberg K, Jolly S, Maturen KE, Brock KK, Prisciandaro JI. Deformable image registration-based contour propagation yields clinically acceptable plans for MRI-based cervical cancer brachytherapy planning. Brachytherapy; 17(2):360-367, Mar-Apr 2018. e-Pub 01/2018. PMID: 29331573.

2017 Publications

McGrath DM, Lee J, Foltz WD, Samavati N, van der Kwast T, Jewett MA, Chung P, Ménard C, Brock KK. MR elastography to measure the effects of cancer and pathology fixation on prostate biomechanics, and comparison with T 1, T 2 and ADC. Phys Med Biol; 62(3):1126-1148, 02/2017. PMID: 28092638, PMCID: PMC5318143.
Horie M, Saito T, Moseley J, D'Errico L, Salazar P, Nakajima D, Brock KK, Yasufuku K, Binnie M, Keshavjee S, Paul N. The role of biomechanical anatomical modeling via computed tomography for identification of Restrictive Allograft Syndrome. Clin Transplant.; 31(8), 08/2017. e-Pub 07/2017. PMID:28658530.
Pawlicki T, Ayers RG, Brock KK, Clements JB, Curran BH, Dobbins JT, Samei E, Adams E, Martin MC, Schober L. Proposed changes to the American Association of Physicists in Medicine governance. J Appl Clin Med Phys; 18(4):4-6, 07/2017. PMID: 28681449, PMCID: PMC5874933.
Brock KK, Mutic S, McNutt TR, Li H, Kessler ML. Use of image registration and fusion algorithms and techniques in radiotherapy: Report of the AAPM Radiation Therapy Committee Task Group No. 132. Med Phys; 44(7):e43-e76, 07/2017. e-Pub 05/2017. PMID: 28376237.
Velec M, Moseley JL, Svensson S, Hårdemark B, Jaffray DA, Brock KK. Validation of biomechanical deformable image registration in the abdomen, thorax and pelvis in a commercial radiotherapy treatment planning system. Med Phys; 44(7):3407-3417, 07/2017. e-Pub 06/2017. PMID: 28453911, PMCID: PMC5535790.
Chung C, Brock KK. Image-guided radiation therapy: looking beyond what we currently see. Future Oncol; 13(26):2317-2319, 11/2017. e-Pub 11/2017. PMID: 29121781.
Polan DF, Feng M, Lawrence TS, Ten Haken RK, Brock KK. Implementing radiation dose-volume liver response in biomechanical deformable image registration. Int J Radiat Oncol Biol Phys; 99(4):1004-1012, 11/2017. e-Pub 06/2017. PMID: 28864401, PMCID: PMC5654673.
Ma J, Moerland MA, Venkatesan AM, Bathala TK, Kudchadker RJ, Brock KK, Frank SJ. Pulse sequence considerations for simulation and postimplant dosimetry of prostate brachytherapy. Brachytherapy; 16(4):743-753, Jul-Aug 2017. e-Pub 10/2017. PMID: 28063817, PMCID: PMC5880297.

2016 Publications

Samavati N, Velec M, Brock KK. Effect of deformable registration uncertainty on lung SBRT dose accumulation. Med Phys 43(1):233, 1/2016. PMCID: PMC4691248.
Swaminath A, Knox JJ, Brierley JD, Dinniwell R, Wong R, Kassam Z, Kim J, Coolens C, Brock KK, Dawson LA. Changes in liver volume observed following Sorafenib and liver radiation therapy. Int J Radiat Oncol Biol Phys; 94(4):729-737, 03/2016. e-Pub 12/2015. PMID: 26972645.
Matuszak MM, Hadley SW, Feng M, Hayman JA, Brock KK, Burger P, Owen D, Suresh K, Schipper M, Lawrence TS, Moran JM. Enhancing safety and quality through preplanning peer review for patients undergoing stereotactic body radiation therapy. Pract Radiat Oncol; 6(2):e39-46, Mar-Apr 2016. e-Pub 12/2015. PMID: 26746815.
McGrath DM, Lee J, Foltz WD, Samavati N, Jewett MA, van der Kwast T, Chung P, Ménard C, Brock KK. Technical Note: Method to correlate whole-specimen histopathology of radical prostatectomy with diagnostic MR imaging. Med Phys; 43(3):1065-1072, 03/2016. PMID: 26936694, PMCID: PMC4744234.
Cazoulat G, Owen D, Matuszak MM, Balter JM, Brock KK. Biomechanical deformable image registration of longitudinal lung CT images using vessel information. Phys Med Biol; 61(13):4826-3489, 07/2016. e-Pub 06/2016. PMID: 27273115, PMCID: PMC4975156.
Coolens C, Driscoll B, Moseley J, Brock KK, Dawson LA. Feasibility of 4D perfusion CT imaging for the assessment of liver treatment response following SBRT and sorafenib. Adv Radiat Oncol; 1(3):194-203, Jul-Sep 2016. e-Pub 07/2016. PMID: 28740888, PMCID: PMC5514015.
Klein EE, Brock KK, Fontenot J, Yu Y. Technical advances in oncology outside of radiation medicine. Int J Radiat Oncol Biol Phys; 95(5):1323-1326, 08/2016. PMID: 27479719.
Samuels SE, Eisbruch A, Vineberg K, Lee J, Lee C, Matuszak MM, Ten Haken RK, Brock KK. Methods for reducing normal tissue complication probabilities in oropharyngeal cancer: Dose reduction or planning target volume elimination. Int J Radiat Oncol Biol Phys; 96(3):645-652, 11/2016. PMID: 27681761.
Liss AL, Marsh RB, Kapadia NS, McShan DL, Rogers VE, Balter JM, Moran JM, Brock KK, Schipper MJ, Jagsi R, Griffith KA, Flaherty KR, Frey KA, Pierce J. Decreased lung perfusion after breast/chest wall irradiation: Quantitative results from a prospective clinical trial. Int J Radiat Oncol Biol Phys; 97(2):296-302, 02/2017. e-Pub 10/2016. PMID: 27986344, PMCID: PMC5222748.

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