Publications
Fiacco SV, Kelderhouse LE, Hardy A, Peleg Y, Hu B, Ornelas A, Yang P, Gammon ST, Howell SM, Wang P, Takahashi TT, Millward SW, Roberts RW. Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications. ChemBioChem 17(17):1643-51, 9/2016. e-Pub 7/2016. PMID: 27465925.
Ornelas A, McCullough CR, Lu Z, Zacharias NM, Kelderhouse LE, Gray J, Yang H, Engel BJ, Wang Y, Mao W, Sutton MN, Bhattacharya PK, Bast RC Jr, Millward SW. Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models. BMC Cancer 16(1):824, 2016. PMCID: PMC5080741.
Deyle KM, Farrow B, Qiao Hee Y, Work J, Wong M, Lai B, Umeda A, Millward SW, Nag A, Das S, Heath JR. A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1. Nat Chem 7(5):455-62, 5/2015. e-Pub 4/2015. PMCID: PMC4408887.
Washington MN, Suh G, Orozco AF, Sutton MN, Yang H, Wang Y, Mao W, Millward S, Ornelas A, Atkinson N, Liao W, Bast RC, Lu Z. ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts. Cell Death & Disease 6(8):e1836, 2015. e-Pub 8/2015. PMCID: PMC4558501.
Howell SM, Fiacco SV, Takahashi TT, Jalali-Yazdi F, Millward SW, Hu B, Wang P, Roberts RW. Serum Stable Natural Peptides Designed by mRNA Display. Sci Rep 4:6008, 9/2014. e-Pub 9/2014. PMCID: PMC4168267.
Nag A, Das S, Yu MB, Deyle KM, Millward SW, Heath JR. A Chemical Epitope-Targeting Strategy for Protein Capture Agents: The Serine 474 Epitope of the Kinase Akt2. Angew Chem Int Ed Engl 52(52):13975-9, 12/2013. e-Pub 11/2013. PMCID: PMC4059071.
Millward SW, Agnew HD, Lai B, Lee SS, Lim J, Nag A, Pitram S, Rohde R, Heath JR. Click chemistry: from small molecule discovery to synthetic antibodies. Integr Biol (Camb) 5(1):87-95, 1/2013. e-Pub 7/2012. PMCID: PMC3716466.
Walker CM, Lee J, Ramirez MS, Schellingerhout D, Millward S, Bankson JA. A catalyzing phantom for reproducible dynamic conversion of hyperpolarized [1-13C]-pyruvate. PLoS One 8(8):e71274, 2013. e-Pub 8/2013. PMCID: PMC3744565.
Millward SW, Henning RK, Kwong GA, Pitram S, Agnew HD, Deyle KM, Nag A, Hein J, Lee SS, Lim J, Pfeilsticker JA, Sharpless KB, Heath JR. Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1. J Am Chem Soc 133(45):18280-8, 11/2011. e-Pub 10/2011. PMCID: PMC3651860.
Agnew HD, Rohde RD, Millward SW, Nag A, Yeo WS, Hein JE, Pitram SM, Tariq AA, Burns VM, Krom RJ, Fokin VV, Sharpless KB, Heath JR. Iterative in situ click chemistry creates antibody-like protein-capture agents. Angew Chem Int Ed Engl 48(27):4944-8, 2009. PMCID: PMC3716464.
Millward SW, Fiacco S, Austin RJ, Roberts RW. Design of cyclic peptides that bind protein surfaces with antibody-like affinity. ACS Chem Biol 2(9):625-34, 9/2007. PMCID: PMC3747792.
Millward SW, Takahashi TT, Roberts RW. A general route for post-translational cyclization of mRNA display libraries. J Am Chem Soc 127(41):14142-3, 10/2005. PMID: 16218582.
Frankel A, Millward SW, Roberts RW. Encodamers: unnatural peptide oligomers encoded in RNA. Chem Biol 10(11):1043-50, 11/2003. PMID: 14652071.
Li S, Millward SW, Roberts R. In vitro selection of mRNA display libraries containing an unnatural amino acid. Journal of American Chemical Society 124(34):9972-3, 2002. PMID: 12188645.