Publications

Pancreatic Epithelial IL17/IL17RA Signaling Drives B7-H4 Expression to Promote Tumorigenesis    
Susana Castro-Pando, Rian M Howell, Le Li, Marilina Mascaro, Erika Y Faraoni, Olivereen Le Roux, David Romanin, Virginia Tahan, Erick Riquelme, Yu Zhang, Jay K Kolls, James P Allison, Guillermina Lozano, Seyed J Moghaddam, Florencia McAllister
Cancer Immunology Research (2024); 12 (9): 1170-1183                    

The liver casts a wide NET for metastatic pancreatic cancer
Le Li, Florencia McAllister & Anirban Maitra
Nature Medicine (2024); 30: 2125-2126

Gut epithelial Interleukin-17 receptor A signaling can modulate distant tumors growth through microbial regulation 
Vidhi Chandra, Le Li, Olivereen Le Roux, Yu Zhang, Rian M Howell, Dhwani N Rupani, Seyda Baydogan, Haiyan D Miller, Erick Riquelme, Joseph Petrosino, Michael P Kim, Krishna PL Bhat, James R White, Jay K Kolls, Yuliya Pylayeva-Gupta, Florencia McAllister
Cancer Cell (2024); 42 (1): 85-100

Germline testing identifies pathogenic/likely pathogenic variants in patients with pancreatic neuroendocrine tumors
Chirayu Mohindroo, Seyda Baydogan, Parul Agarwal, Dan Laheru, Robin Wright, Laura R Prakash, Maureen E Mork, Alison P Klein, Jess Maxwell, Katz Matthew HG, Arvind Dasari, Michael P Kim, Jin He, Florencia McAllister, Jesus-Acosta Ana De
Endocrine Abstracts (2023); 98

Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias
Erick Riquelme, Rian M Howell, Florencia McAllister
Cancer Research; 83 (22): 3670-3672

Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome
Nan Deng, Laura Reyes-Uribe, Johannes F Fahrmann, Whittney S Thoman, Mark F Munsell, Jennifer B Dennison, Eunice Murage, Ranran Wu, Ernest T Hawk, Selvi Thirumurthi, Patrick M Lynch, Christina M Dieli-Conwright, Alexander J Lazar, Sonali Jindal, Khoi Chu, Manoj Chelvanambi, Karen Basen-Engquist, Yisheng Li, Jennifer A Wargo, Florencia McAllister, James P Allison, Padmanee Sharma, Krishna M Sinha, Samir Hanash, Susan C Gilchrist, Eduardo Vilar
Clinical Cancer Research; 29 (21): 4361-4372

Gut microbiota aggravates neutrophil extracellular traps-induced pancreatic injury in hypertriglyceridemic pancreatitis
Guanqun Li, Liwei Liu, Tianqi Lu, Yuhang Sui, Can Zhang, Yongwei Wang, Tao Zhang, Yu Xie, Peng Xiao, Zhongjie Zhao, Chundong Cheng, Jisheng Hu, Hongze Chen, Dongbo Xue, Hua Chen, Gang Wang, Rui Kong, Hongtao Tan, Xuewei Bai, Zhibo Li, Florencia McAllister, Le Li, Bei Sun
Nature Communications; 14 (1): 6179

Prevalence of germline variants in patients with pancreatic neuroendocrine tumors
Chirayu Mohindroo, Seyda Baydogan, Parul Agarwal, Dan Laheru, Robin Wright, Laura Prakash, Maureen E Mork, Alison Klein, Jess Maxwell, Matthew HG Katz, Arvind Dasari, Michael Paul Kim, Jin He, Florencia McAllister, Ana De Jesus-Acosta
Journal of Clinical Oncology; 41 (16): 4135

CD73-dependent adenosine signaling through Adora2b drives immunosuppression in ductal pancreatic cancer
Erika Y Faraoni, Kanchan Singh, Vidhi Chandra, Olivereen Le Roux, Yulin Dai, Ismet Sahin, Baylee J O'Brien, Lincoln N Strickland, Le Li, Emily Vucic, Amanda N Warner, Melissa Pruski, Trent Clark, George Van Buren, Nirav C Thosani, John S Bynon, Curtis J Wray, Dafna Bar-Sagi, Kyle L Poulsen, Lana A Vornik, Michelle I Savage, Shizuko Sei, Altaf Mohammed, Zhongming Zhao, Powel H Brown, Tingting Mills, Holger K Eltzschig, Florencia McAllister, Jennifer M Bailey-Lundberg
Cancer Research; 83 (7): 1111-1127

A gut reaction can tune tumour fate during chemotherapy
Le Li, Florencia McAllister
Nature; 615 (7950): 36-37

Transient CA19-9 Elevation Post-COVID-19 Vaccine and Infection: A Case Series
Seyda Baydogan, R Wright, RT Kottoor, Michael Kim, MS Bhutani, Florencia McAllister
Gastro Hep Advances; 2 (7): 946-947

Optimized surveillance intervals for low-risk side-branch intraductal papillary mucinous neoplasms
M Zhao, VF Hill, LR Prakash, MS Bhutani, ST Chari, F McAllister, JE Maxwell, CD Tzeng, N Ikoma, JE Lee, MHG Katz, MP Kim
HPB; 25: S9

Prospective characterization of oral and gut microbiome in a high-risk pancreatic cancer cohort.
Seyda Baydogan, Chirayu Mohindroo, Maria Fernanda Montiel, Joseph Petrosino, Anirban Maitra, Michael Paul Kim, Manoop S Bhutani, James R White, Florencia McAllister
Journal of Clinical Oncology; 41 (4): 691

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma
Ya’an Kang, Jenying Deng, Jianhua Ling, Xinqun Li, Yi-Ju Chiang, Eugene J Koay, Huamin Wang, Jared K Burks, Paul J Chiao, Mark W Hurd, Manoop S Bhutani, Jeffrey H Lee, Brian R Weston, Anirban Maitra, Naruhiko Ikoma, Ching-Wei D Tzeng, Jeffrey E Lee, Ronald A DePinho, Robert A Wolff, Shubham Pant, Florencia McAllister, Matthew HG Katz, Jason B Fleming, Michael P Kim
Journal of Clinical Investigation; 132 (24): e151604

Bacterial and fungal characterization of pancreatic adenocarcinoma from Endoscopic Ultrasound-guided biopsies
Robin D Wright, Thais F Bartelli, Seyda Baydogan, James Robert White, Michael P Kim, Manoop S Bhutani, Florencia McAllister
Frontiers in Immunology; 14: 1268376

Adar1 deletion causes degeneration of the exocrine pancreas via MAVS-dependent interferon signaling
Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister
Development (2023); 150 (2): dev201097.

The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice
Chirayu Mohindroo, Ana De Jesus-Acosta, Matthew B Yurgelun, Anirban Maitra, Maureen Mork, Florencia McAllister
Surgical Pathology Clinics (2022); 15 (3): 491-502

Challenges and opportunities for physician-scientists in advancing cancer research
NE Davidson, RJ Gilbertson, A Letai, RL Levine, F McAllister, LL Siu
Trends in Cancer (2022); 8 (8): 615-619         

Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer
Emma Kurz, Carolina Alcantara Hirsch, Tanner Dalton, Sorin Alberto Shadaloey, Alireza Khodadadi-Jamayran, George Miller, Sumedha Pareek, Hajar Rajaei, Chirayu Mohindroo, Seyda Baydogan, An Ngo-Huang, Nathan Parker, Matthew HG Katz, Maria Petzel, Emily Vucic, Florencia McAllister, Keri Schadler, Rafael Winograd, Dafna Bar-Sagi
Cancer Cell (2022); 40 (7): 720-737             

Too much water drowned the miller: Akkermansia determines immunotherapy responses
Le Li, Florencia McAllister
Cell Reports Medicine 3 (5): 100642         

Implementation of a Video-based Remote Germline Testing for Individuals With Pancreatic Ductal Adenocarcinoma
Saumya Kasliwal, Seyda Baydogan, Devon Harrison, Maureen Mork, Anirban Maitra, Florencia Mcallister
Gastroenterology (2022); 163 (1): 316-318           

Immunotherapy in pancreatic adenocarcinoma: beyond “Copy/Paste”
Robert Hester, Pawel K Mazur, Florencia McAllister
Clinical Cancer Research (2021); 27 (23): 6287-6297          

Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE
Study Genetic Education and Testing for Pancreatic Cancer
C Sloane Furniss, Matthew B Yurgelun, Chinedu Ukaegbu, Pamela E Constantinou, Catherine C Lafferty, Eliana R Talcove-Berko, Alison N Schwartz, Jill E Stopfer, Meghan Underhill-Blazey, Barbara Kenner, Scott H Nelson, Sydney Okumura, Sherman Law, Alicia Y Zhou, Tara B Coffin, Nicolette J Rodriguez, Hajime Uno, Allyson J Ocean, Florencia McAllister, Andrew M Lowy, Scott M Lippman, Alison P Klein, Lisa Madlensky, Gloria M Petersen, Judy E Garber, Michael G Goggins, Anirban Maitra, Sapna Syngal
Cancer Prevention Research (2021); 14 (11): 1021-1032  

The Human Microbiomes in Pancreatic Cancer: Towards Evidence-Based Manipulation Strategies?
Giovanni Brandi, Silvia Turroni, Florencia McAllister, Giorgio Frega
International Journal of Molecular Sciences (2021); 22 (18): 9914

Bacteria and fungi: The counteracting modulators of immune responses to radiation therapy in cancer
Erick Riquelme, Florencia McAllister
Cancer Cell (2021); 39 (9): 1173-1175       

Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast
Vidya C Sinha, Amanda L Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A Zebala, Dean Y Maeda, Florencia McAllister, Helen Piwnica-Worms
Nature Communications (2021); 12 (1): 1-17

Antibiotic use influences outcomes in advanced pancreatic adenocarcinoma patients
Chirayu Mohindroo, Merve Hasanov, Jane E Rogers, Wenli Dong, Laura R Prakash, Seyda Baydogan, Jonathan D Mizrahi, Michael J Overman, Gauri R Varadhachary, Robert A Wolff, Milind M Javle, David R Fogelman, Michael T Lotze, Michael P Kim, Matthew HG Katz, Shubham Pant, Ching‐Wei D Tzeng, Florencia McAllister
Cancer Medicine (2021); 10 (15): 5041-5050         

Therapeutic potential of microbial modulation in pancreatic cancer
Vidhi Chandra, Florencia McAllister
Gut (2021); 70 (8): 1419-1425     

Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis: Oncogenic
KRAS and Mutant p53 Cooperate to Drive Metastasis
Michael P Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra L Allton, Tara G Hughes, Christian Siangco, Jithesh J Augustine, Ya'an Kang, Joy M McDaniel, Shunbin Xiong, Eugene J Koay, Florencia McAllister, Christopher A Bristow, Timothy P Heffernan, Anirban Maitra, Bin Liu, Michelle C Barton, Amanda R Wasylishen, Jason B Fleming, Guillermina Lozano
Cancer Discovery (2021); 11 (8): 2094-2111           

Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer
Kanchan Singh, Melissa Pruski, Rachael Bland, Mamoun Younes, Sushovan Guha, Nirav Thosani, Anirban Maitra, Brooks D Cash, Florencia McAllister, Craig D Logsdon, Jeffrey T Chang, Jennifer M Bailey-Lundberg
Laboratory Investigation (2021); 101 (2): 177-192

Augmented lipocalin-2 is associated with chronic obstructive pulmonary disease and counteracts lung adenocarcinoma development
Warapen Treekitkarnmongkol, Maya Hassane, Ansam Sinjab, Kyle Chang, Kieko Hara, Zahraa Rahal, Jiexin Zhang, Wei Lu, Smruthy Sivakumar, Tina L McDowell, Jacob Kantrowitz, Jianling Zhou, Wenhua Lang, Li Xu, Joshua K Ochieng, Sayuri Nunomura-Nakamura, Shanshan Deng, Carmen Behrens, Maria Gabriela Raso, Junya Fukuoka, Alexandre Reuben, Edwin J Ostrin, Edwin Parra, Luisa M Solis, Avrum E Spira, Florencia McAllister, Tina Cascone, Ignacio I Wistuba, Seyed Javad Moghaddam, Paul A Scheet, Junya Fujimoto, Humam Kadara
American Journal of Respiratory and Critical Care Medicine (2021); 203 (1): 90-101

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer
Yu Zhang, Vidhi Chandra, Erick Riquelme Sanchez, Prasanta Dutta, Pompeyo R Quesada, Amanda Rakoski, Michelle Zoltan, Nivedita Arora, Seyda Baydogan, William Horne, Jared Burks, Hanwen Xu, Perwez Hussain, Huamin Wang, Sonal Gupta, Anirban Maitra, Jennifer M Bailey, Seyed J Moghaddam, Sulagna Banerjee, Ismet Sahin, Pratip Bhattacharya, Florencia McAllister
Journal of Experimental Medicine (2020); 217 (12)

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo
Amanda R Wasylishen, Chang Sun, Sydney M Moyer, Yuan Qi, Gilda P Chau, Neeraj K Aryal, Florencia McAllister, Michael P Kim, Michelle C Barton, Jeannelyn S Estrella, Xiaoping Su, Guillermina Lozano
Science Advances (2020); 6 (32)

Modified gemcitabine plus nab‐paclitaxel regimen in advanced pancreatic ductal adenocarcinoma
Jane E Rogers, Jonathan D Mizrahi, Lianchun Xiao, Chirayu Mohindroo, Rachna T Shroff, Robert Wolff, Gauri R Varadhachary, Milind M Javle, Michael Overman, David R Fogelman, Kanwal PS Raghav, Shubham Pant, Florencia McAllister
Cancer Medicine (2020); 9 (15): 5406-5415           

Uso de plasma de convalecientes para tratamiento de COVID-19: Historia y evidencia
Florencia McAllister, Adriana Mantegazza, Félix Garzón, Viviana Rotbaum, Graciela Remondino, Mónica Vazquez Larsson, Jorge Geffner, Gabriel A Rabinovich, Laura Bover
MEDICINA (Buenos Aires) (2020); 80: 82-86          

Targeting potential drivers of COVID-19: Neutrophil extracellular traps
Betsy J Barnes, Jose M Adrover, Amelia Baxter-Stoltzfus, Alain Borczuk, Jonathan Cools-Lartigue, James M Crawford, Juliane Daßler-Plenker, Philippe Guerci, Caroline Huynh, Jason S Knight, Massimo Loda, Mark R Looney, Florencia McAllister, Roni Rayes, Stephane Renaud, Simon Rousseau, Steven Salvatore, Robert E Schwartz, Jonathan D Spicer, Christian C Yost, Andrew Weber, Yu Zuo, Mikala Egeblad
Journal of Experimental Medicine (2020); 217 (6)             

Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy
Prasanta Dutta, Susana Castro Pando, Marilina Mascaro, Erick Riquelme, Michelle Zoltan, Niki M Zacharias, Seth T Gammon, David Piwnica-Worms, Mark D Pagel, Subrata Sen, Anirban Maitra, Shayan Shams, Florencia McAllister, Pratip K Bhattacharya
International Journal of Molecular Sciences (2020); 21(10): 3722

Microbial dysbiosis and polyamine metabolism as predictive markers for early detection of pancreatic cancer
Roberto Mendez, Kousik Kesh, Nivedita Arora, Leá Di Martino, Florencia McAllister, Nipun Merchant, Sulagna Banerjee, Santanu Banerjee
Carcinogenesis (2020); 41 (5): 561-570

Germline DNA Sequencing Reveals Novel Mutations Predictive of Overall Survival in a Cohort of Patients with Pancreatic CancerNovel Mutations Predict Survival in Pancreatic Cancer
Jennifer B Goldstein, Li Zhao, Xuemei Wang, Yael Ghelman, Michael J Overman, Milind M Javle, Rachna T Shroff, Gauri R Varadhachary, Robert A Wolff, Florencia McAllister, Andrew Futreal, David R Fogelman
Clinical Cancer Research (2020); 26 (6): 1385-1394

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma
De Jesus-Acosta, Elizabeth A Sugar, Peter J O’Dwyer, Ramesh K Ramanathan, Daniel D Von Hoff, Zeshaan Rasheed, Lei Zheng, Asma Begum, Robert Anders, Anirban Maitra, Florencia McAllister, NV Rajeshkumar, Shinichi Yabuuchi, Roeland F De Wilde, Bhavina Batukbhai, Ismet Sahin, Daniel A Laheru
British Journal of Cancer (2020); 122 (4): 498-505               

Quality of life impact of EUS in patients at risk for developing pancreatic cancer
Irina M Cazacu, Adriana A Luzuriaga Chavez, Tito R Mendoza, Wei Qiao, Ben S Singh, Raza H Bokhari, Adrian Saftoiu, Jeffrey H Lee, Brian Weston, John R Stroehlein, Michael P Kim, Matthew HG Katz, Anirban Maitra, Florencia McAllister, Manoop S Bhutani
Endoscopic Ultrasound (2020); 9 (1): 53 

Mst1/2 kinases restrain transformation in a novel transgenic model of Ras driven non-small cell lung cancer
Kanchan Singh, Melissa A Pruski, Kishore Polireddy, Neal CJones, Qingzhen g Chen, Jun Yao, Wasim A Dar, Florencia McAllister, Cynthia Ju, Holger K Eltzschig, Mamoun Younes, Cesar Moran, Harry Karmouty-Quintana, Haoqiang Ying, Jennifer M Bailey
Oncogene (2020); 39 (5): 1152-1164        

The tumor microbiome in pancreatic cancer: bacteria and beyond
Florencia McAllister, Md Abdul Wadud Khan, Beth Helmink, Jennifer A Wargo
Cancer Cell (2019); 36 (6): 577-579           

Tumor microbiome diversity and composition influence pancreatic cancer outcomes
Erick Riquelme, Yu Zhang, Liangliang Zhang, Maria Montiel, Michelle Zoltan, Wenli Dong, Pompeyo Quesada, Ismet Sahin, Vidhi Chandra, Anthony San Lucas, Paul Scheet, Hanwen Xu, Samir M Hanash, Lei Feng, Jared K Burks, Kim-Anh Do, Christine B Peterson, Deborah Nejman, Ching-Wei D Tzeng, Michael P Kim, Cynthia L Sears, Nadim Ajami, Joseph Petrosino, Laura D Wood, Anirban Maitra, Ravid Straussman, Matthew Katz, James Robert White, Robert Jenq, Jennifer Wargo, Florencia McAllister
Cell (2019); 178 (4): 795-806       

Benefit of gemcitabine/nab-paclitaxel rescue of patients with borderline resectable or locally advanced pancreatic adenocarcinoma after early failure of FOLFIRINOX
Timothy J Vreeland, Florencia McAllister, Sanaz Javadi, Laura R Prakash, David R Fogelman, Linus Ho, Gauri Varadhachary, Thomas A Aloia, Jean-Nicolas Vauthey, Jeffrey E Lee, Michael Kim, Matthew HG Katz, Ching-Wei D Tzeng
Pancreas (2019); 48 (6): 837        

Combining hyperpolarized real-time metabolic imaging and NMR spectroscopy to identify metabolic biomarkers in pancreatic cancer
Prasanta Dutta, Mayrim R Perez, Jaehyuk Lee, Yaan Kang, Michael Pratt, Travis C Salzillo, Joseph Weygand, Niki M Zacharias, Seth T Gammon, Eugene J Koay, Michael Kim, Florencia McAllister, Subrata Sen, Anirban Maitra, David Piwnica-Worms, Jason B Fleming, Pratip K Bhattacharya
Journal of Proteome Research (2019); 18 (7): 2826-2834 

Assessing therapeutic efficacy in real-time by hyperpolarized magnetic resonance metabolic imaging
Prasanta Dutta, Travis C Salzillo, Shivanand Pudakalakatti, Seth T Gammon, Benny A Kaipparettu, Florencia McAllister, Shawn Wagner, Daniel E Frigo, Christopher J Logothetis, Niki M Zacharias, Pratip K Bhattacharya
Cells (2019); 8 (4): 340   

High Prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer: Hereditary Syndromes in Early-Onset Pancreatic Cancer
Sarah A Bannon, Maria F Montiel, Jennifer B Goldstein, Wenli Dong, Maureen E Mork, Ester Borras, Merve Hasanov, Gauri R Varadhachary, Anirban Maitra, Matthew H Katz, Lei Feng, Andrew Futreal, David R Fogelman, Eduardo Vilar, Florencia McAllister
Cancer Prevention Research (2018); 11 (11): 679-686      

Immune profiling of premalignant lesions in patients with lynch syndrome
Kyle Chang, Melissa W Taggart, Laura Reyes-Uribe, Ester Borras, Erick Riquelme, Reagan M Barnett, Guido Leoni, F Anthony San Lucas, Maria T Catanese, Federica Mori, Maria G Diodoro, Y Nancy You, Ernest T Hawk, Jason Roszik, Paul Scheet, Scott Kopetz, Alfredo Nicosia, Elisa Scarselli, Patrick M Lynch, Florencia McAllister, Eduardo Vilar
JAMA Oncology (2018); 4 (8): 1085-1092

Immune cell production of interleukin 17 induces stem cell features of pancreatic intraepithelial neoplasia cells
Yu Zhang, Michelle Zoltan, Erick Riquelme, Hanwen Xu, Ismet Sahin, Susana Castro-Pando, Maria Fernanda Montiel, Kyle Chang, Zhengyu Jiang, Jianhua Ling, Sonal Gupta, William Horne, Melissa Pruski, Huamin Wang, Shao-Cong Sun, Guillermina Lozano, Paul Chiao, Anirban Maitra, Steven D Leach, Jay K Kolls, Eduardo Vilar, Timothy C Wang, Jennifer M Bailey, Florencia McAllister
Gastroenterology (2018); 155 (1): 210-223

IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
Nese Unver, Florencia McAllister
Cytokine & Growth Factor Reviews (2018); 41: 10-17

Immunotherapy for pancreatic cancer: more than just a gut feeling
Erick Riquelme, Anirban Maitra, Florencia McAllister
Cancer Discovery (2018); 8 (4): 386-388

Bacteroides fragilis toxin coordinates a pro-carcinogenic inflammatory cascade via targeting of colonic epithelial cells
Liam Chung, Erik Thiele Orberg, Abby L Geis, June L Chan, Kai Fu, Christina E DeStefano Shields, Christine M Dejea, Payam Fathi, Jie Chen, Benjamin B Finard, Ada J Tam, Florencia McAllister, Hongni Fan, Xinqun Wu, Sudipto Ganguly, Andriana Lebid, Paul Metz, Sara W Van Meerbeke, David L Huso, Elizabeth C Wick, Drew M Pardoll, Fengyi Wan, Shaoguang Wu, Cynthia L Sears, Franck Housseau
Cell Host & Microbe (2018); 23 (2): 203-214

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
Vancheswaran Gopalakrishnan, Christine N Spencer, Luigi Nezi, Alexandre Reuben, MC Andrews, TV Karpinets, PA Prieto, D Vicente, Karen Hoffman, Spencer Christopher Wei, AP Cogdill, L Zhao, CW Hudgens, DS Hutchinson, Teresa Manzo, M Petaccia de Macedo, T Cotechini, T Kumar, WS Chen, SM Reddy, R Szczepaniak Sloane, J Galloway-Pena, H Jiang, PL Chen, EJ Shpall, K Rezvani, AM Alousi, RF Chemaly, S Shelburne, Luis M Vence, PC Okhuysen, VB Jensen, AG Swennes, F McAllister, E Marcelo Riquelme Sanchez, Y Zhang, Emmanuelle Le Chatelier, L Zitvogel, Nicolas Pons, JL Austin-Breneman, LE Haydu, EM Burton, JM Gardner, E Sirmans, Jianhua Hu, AJ Lazar, T Tsujikawa, A Diab, H Tawbi, IC Glitza, Wen-Jen Hwu, SP Patel, SE Woodman, RN Amaria, MA Davies, JE Gershenwald, P Hwu, JE Lee, J Zhang, LM Coussens, ZA Cooper, PA Futreal, CR Daniel, NJ Ajami, JF Petrosino, MT Tetzlaff, Pradeep Sharma, JP Allison, RR Jenq, JA Wargo
Science (2018); 359 (6371): 97-103          

Tumor Spheres Quantification with Smoothed Euclidean Distance Transform
Ismet Sahin, Yu Zhang, Florencia McAllister
Journal of Molecular Imaging & Dynamics (2018); 8 (1)

CTLA-4/CD80 pathway regulates T cell infiltration into pancreatic cancer
Fee Bengsch, Dawson M Knoblock, Anni Liu, Florencia McAllister, Gregory L Beatty
Cancer Immunology, Immunotherapy (2017); 66 (12): 1609-1617

Current status and future directions for screening patients at high risk for pancreatic cancer
Florencia McAllister, Maria F Montiel, Guneesh S Uberoi, Angad S Uberoi, Anirban Maitra, Manoop S Bhutani
Gastroenterology & Hepatology (2017); 13 (5): 268

p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
JM Bailey, AM Hendley, KJ Lafaro, MA Pruski, NC Jones, J Alsina, M Younes, A Maitra, F McAllister, CA Iacobuzio-Donahue, SD Leach
Oncogene (2016); 35 (32): 4282-4288

Genomic landscape of colorectal mucosa and adenomas
Ester Borras, F Anthony San Lucas, Kyle Chang, Ruoji Zhou, Gita Masand, Jerry Fowler, Maureen E Mork, Y Nancy You, Melissa W Taggart, Florencia McAllister, David A Jones, Gareth E Davies, Winfried Edelmann, Erik A Ehli, Patrick M Lynch, Ernest T Hawk, Gabriel Capella, Paul Scheet, Eduardo Vilar
Cancer Prevention Research (2016); 9 (6): 417-427

Emerging strategies for cancer immunoprevention
JC Roeser, SD Leach, F McAllister
Oncogene (2015); 34 (50): 6029-6039

CD4+ T cell–independent DNA vaccination against opportunistic infections
Mingquan Zheng, Alistair J Ramsay, Myles B Robichaux, Corrine Kliment, Christopher Crowe, Rekha R Rapaka, Chad Steele, Florencia McAllister, Judd E Shellito, Luis Marrero, Paul Schwarzenberger, Qiu Zhong, Jay K Kolls
The Journal of Clinical Investigation (2015); 125 (3), 1364

Th17 cytokines in non‐melanoma skin cancer
Florencia McAllister, Jay K Kolls
European Journal of Immunology (2015); 45 (3): 692-694

Microbiota organization is a distinct feature of proximal colorectal cancers
Christine M Dejea, Elizabeth C Wick, Elizabeth M Hechenbleikner, James R White, Jessica L Mark Welch, Blair J Rossetti, Scott N Peterson, Erik C Snesrud, Gary G Borisy, Mark Lazarev, Ellen Stein, Jamuna Vadivelu, April C Roslani, Ausuma A Malik, Jane W Wanyiri, Khean L Goh, Iyadorai Thevambiga, Kai Fu, Fengyi Wan, Nicolas Llosa, Franck Housseau, Katharine Romans, XinQun Wu, Florencia McAllister, Shaoguang Wu, Bert Vogelstein, Kenneth W Kinzler, Drew M Pardoll, Cynthia L Sears 
Proceedings of the National Academy of Sciences (2014); 111 (51): 18321-18326

Targeting IL-17 for pancreatic cancer prevention
Florencia McAllister, Steven D Leach
Oncotarget (2014); 5 (20): 9530

Immune cells in pancreatic cancer: joining the dark side
Yaqing Zhang, Florencia McAllister, Marina Pasca di Magliano
Oncoimmunology (2014); 3 (6): e29125

dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial
Florencia McAllister, Danielle M Pineda, Masaya Jimbo, Shruti Lal, Richard A Burkhart, Jennifer Moughan, Kathryn A Winter, Kotb Abdelmohsen, Myriam Gorospe, Ana de Jesus Acosta, Rachana H Lankapalli, Jordan M Winter, Charles J Yeo, Agnieska K Witkiewicz, Christine A Iacobuzio-Donahue, Daniel Laheru, Jonathan R Brody
Cancer Biology & Therapy (2014); 15 (6): 688-698

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia
Florencia McAllister, Jennifer M Bailey, Janivette Alsina, Christopher J Nirschl, Rajni Sharma, Hongni Fan, Yanique Rattigan, Jeffrey C Roeser, Rachana H Lankapalli, Hao Zhang, Elizabeth M Jaffee, Charles G Drake, Franck Housseau, Anirban Maitra, Jay K Kolls, Cynthia L Sears, Drew M Pardoll, Steven D Leach
Cancer Cell (2014); 25 (5): 621-637

DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer
Jennifer M Bailey, Janivette Alsina, Zeshaan A Rasheed, Florencia M McAllister, Ya–Yuan Fu, Ruben Plentz, Hao Zhang, Pankaj J Pasricha, Nabeel Bardeesy, William Matsui, Anirban Maitra, Steven D Leach
Gastroenterology (2014) 146 (1), 245-256

Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer
Daniel Laheru, Preeti Shah, NV Rajeshkumar, Florencia McAllister, Gretchen Taylor, Howard Goldsweig, Dung T Le, Ross Donehower, Antonio Jimeno, Sheila Linden, Ming Zhao, Dongweon Song, Michelle A Rudek, Manuel Hidalgo
Investigational New Drugs (2012); 30 (6): 2391-2399

EMT and dissemination precede pancreatic tumor formation
Andrew D Rhim, Emily T Mirek, Nicole M Aiello, Anirban Maitra, Jennifer M Bailey, Florencia McAllister, Maximilian Reichert, Gregory L Beatty, Anil K Rustgi, Robert H Vonderheide, Steven D Leach, Ben Z Stanger
Cell (2012); 148 (1-2): 349-361

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
Shaoguang Wu, Ki-Jong Rhee, Emilia Albesiano, Shervin Rabizadeh, Xinqun Wu, Hung-Rong Yen, David L Huso, Frederick L Brancati, Elizabeth Wick, Florencia McAllister, Franck Housseau, Drew M Pardoll, Cynthia L Sears
Nature Medicine (2009); 15 (9): 1016-1022

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
Shean J Aujla, Yvonne R Chan, Mingquan Zheng, Mingjian Fei, David J Askew, Derek A Pociask, Todd A Reinhart, Florencia McAllister, Jennifer Edeal, Kristi Gaus, Shahid Husain, James L Kreindler, Patricia J Dubin, Joseph M Pilewski, Mike M Myerburg, Carol A Mason, Yoichiro Iwakura, Jay K Kolls
Nature Medicine (2008); 14 (3): 275-281

Chemokines orchestrate leukocyte trafficking in inflammatory bowel disease
Wenwei Zhong, Jay K Kolls, Hong Chen, Florencia McAllister, Peter D Oliver, Zili Zhang
Frontiers in Bioscience-Landmark (2008); 13 (5): 1654-1664

Is cystic fibrosis a TH17 disease?
PJ Dubin, F McAllister, JK Kolls
Inflammation Research (2007); 56 (6): 221-227

Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia
Laura McKinley, Alison J Logar, Florencia McAllister, Mingquan Zheng, Chad Steele, Jay K Kolls
The Journal of Immunology (2006); 177 (9): 6215-6226

CXCR3 and IFN protein-10 in Pneumocystis pneumonia
Florencia McAllister, Sanbao Ruan, Chad Steele, Mingquan Zheng, Laura McKinley, Lauren Ulrich, Luis Marrero, Judd E Shellito, Jay K Kolls
The Journal of Immunology (2006); 177 (3): 1846-1854   

CD4+ T cell–independent DNA vaccination against opportunistic infections
Mingquan Zheng, Alistair J Ramsay, Myles B Robichaux, Karen A Norris, Corrine Kliment, Christopher Crowe, Rekha R Rapaka, Chad Steele, Florencia McAllister, Judd E Shellito, Luis Marrero, Paul Schwarzenberger, Qiu Zhong, Jay K Kolls
The Journal of Clinical Investigation (2005); 115 (12): 3536-3544  

In Vitro Effector Activity of Pneumocystis murina-Specific T-Cytotoxic-1 CD8+ T Cells: Role of Granulocyte-Macrophage Colony-Stimulating Factor
Florencia McAllister, Chad Steele, Mingquan Zheng, Judd E Shellito, Jay K Kolls
Infection and Immunity (2005); 73 (11): 7450-7457

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
Muneo Numasaki, Mika Watanabe, Takashi Suzuki, Hidenori Takahashi, Akira Nakamura, Florencia McAllister, Takanori Hishinuma, Junichi Goto, Michael T Lotze, Jay K Kolls, Hidetada Sasaki
The Journal of Immunology (2005); 175 (9): 6177-6189

Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
Florencia McAllister, Adam Henry, James L Kreindler, Patricia J Dubin, Lauren Ulrich, Chad Steele, Jonathan D Finder, Joseph M Pilewski, Beatriz M Carreno, Samuel J Goldman, Jaana Pirhonen, Jay K Kolls
The Journal of Immunology (2005); 175 (1): 404-412        

IL-17 Enhances the Net Angiogenic Activity
Takanori Hishinuma, Junichi Goto, Michael T Lotze, Jay K Hidenori Takahashi, Akira Nakamura, Florencia McAllister, Muneo Numasaki, Mika Watanabe, Takashi Suzuki
Journal of Immunology (2005); 175: 6177-6189

T cytotoxic-1 CD8+ T cells are effector cells against pneumocystis in mice
Florencia McAllister, Chad Steele, Mingquan Zheng, Erana Young, Judd E Shellito, Luis Marrero, Jay K Kolls
The Journal of Immunology (2004); 172 (2): 1132-1138