Lin Laboratory
Steven H. Lin, M.D., Ph.D.
Principal Investigator
Areas of Research
- Radiation Oncology
- Lung Cancer
- Esophageal Cancer
- Immunotherapy
The Lin Laboratory has several lines of research. The first is to identify novel agents to combine with radiation to enhance treatment effects through the application of high-throughput screening methods. The second is identifying novel gene targets that could enhance the systemic immune response in combination with radiation therapy. Third, the lab is seeking ways through imaging or blood-based markers to assess response to treatment for lung and esophageal cancer patients.
Funding Support
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Phase I Trial Combining Trametinib with Chemoradiation in Kras Mutant Lung Cancer (NIH/NCI)
Principal Investigator
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Research and Development of Novel Radiation Sensitizers (STCube Pharmaceuticals Inc.)
Principal Investigator
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Diffusion-Weighted Magnetic Resonance Imaging for Early Response Assessment of Neoadjuvant Chemoradiation Therapy in patients with Esophageal Carcinoma (MD Anderson)
Co-Investigator
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Radiogenomic Predictor of Pathologic Response and Recurrence in Esophageal Cancer Patients (R. Lee Clark Fellowship)
Principal Investigator
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GUARDIAN-1 Trial: A Phase I Study of Genetespib in Combination with Chemoradiation for Stage II-III Esophageal Carcinoma (Synta Pharmaceuticals)
Principal Investigator
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Enhancing Chemoradiation Efficacy through Unbiased Drug Discovery Approaches (NIH/NCI)
Principal Investigator
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Southwest Early Clinical Trials Consortium (NIH/NCI)
Co-Investigator
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Mitigating High Grade Radiation-induced Lymphopenia Through Pretreatment Autologous Lymphocyte Infusion (NIH/NCI)
Principal Investigator
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Targeting ferroptosis in radioresistance in lung cancer: mechanism and preclinical translation (NIH/NCI)
Co-Principal Investigator
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Streamlined and comprehensive circulating tumor exosome profiling by microfluidic arrayed nanoplasmonic sensors and actuators (NIH/NIBIB)
Co-Principal Investigator
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Integrating patient-specific clinical and biological factors towards individualizing utilization of proton and photon radiation therapy (NIH/NCI)
Project Leader
Contact Us
Steven H. Lin, M.D., Ph.D.
Professor
Department of Radiation Oncology
Division of Radiation Oncology
6565 MD Anderson Blvd.
Houston, TX 77030
Email: shlin@mdanderson.org
Office: Z7.5044
Lab: Z7.4022
Office phone: 713-563-8490
Lab phone: 713-745-3154
Fax: 713-563-2366