Kopetz Laboratory

Thank you for your interest in our work! As a physician-scientist, I have an in-depth insight into this debilitating disease of colorectal cancer. Our research team focuses on understanding the fundamental signaling and immunobiology of colorectal cancer to develop leading-edge therapies. We have built a translational infrastructure that is critical to our success, including a cutting-edge in vivo team, patient samples, patient-derived models and deep translational profiling of colorectal cancer tumors. We work closely with multiple labs as part of programmatic efforts and collaborate with pharmaceutical partners to advance concepts into clinical trials and have successfully translated key findings into standard of care therapies in the past.

Our research family consists of exceptional clinical-basic and translational colorectal cancer scientists and clinicians. We are experts in taking our exceptional clinical-translational insight from the bed then the bench and back. Our team effort has given us the strategic advantage to make the next leading-edge discoveries and train the next generation basic and clinical-translational scientists.

The lab is supported by multiple National Institutes of Health (NIH)-funded grants, including a GI Specialized Programs of Research Excellence (SPORE) grant, for which I am the contact PI.