Selected Publications
Major Publications
Hu KH, Kuhn NF, Courau T, Tsui J, Samad B, Ha P, Kratz JR, Combes AJ, Krummel MF. Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer. Cell Stem Cell. 2023 Jun 1;30(6):885-903.e10. doi: 10.1016/j.stem.2023.05.001. PMID: 37267918; PMCID: PMC10843988.
Hu K. Spatial Transcriptomics in Inflammation: Dissecting the Immune Response in 3D in Complex Tissues. In Imaging Inflammation. 2023 Mar 31 (pp. 243-279). Cham: Springer International Publishing.
Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S; UCSF COMET Consortium; Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 Mar;591(7848):124-130. doi: 10.1038/s41586-021-03234-7. Epub 2021 Jan 25. Erratum in: Nature. 2021 Aug;596(7872):E8. doi: 10.1038/s41586-021-03718-6. PMID: 33494096; PMCID: PMC8567458.
Hu KH, Eichorst JP, McGinnis CS, Patterson DM, Chow ED, Kersten K, Jameson SC, Gartner ZJ, Rao AA, Krummel MF. ZipSeq: barcoding for real-time mapping of single cell transcriptomes. Nat Methods. 2020 Aug;17(8):833-843. doi: 10.1038/s41592-020-0880-2. Epub 2020 Jul 6. PMID: 32632238; PMCID: PMC7891292.
Hu KH, Butte MJ. T cell activation requires force generation. J Cell Biol. 2016 Jun 6;213(5):535-42. doi: 10.1083/jcb.201511053. Epub 2016 May 30. PMID: 27241914; PMCID: PMC4896056.
Collaborations and Other Publications
Kersten K, Hu KH, Combes AJ, Samad B, Harwin T, Ray A, Rao AA, Cai E, Marchuk K, Artichoker J, Courau T, Shi Q, Belk J, Satpathy AT, Krummel MF. Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer. Cancer Cell. 2022 Jun 13;40(6):624-638.e9. doi: 10.1016/j.ccell.2022.05.004. Epub 2022 May 26. PMID: 35623342; PMCID: PMC9197962.
Thauland TJ, Hu KH, Bruce MA, Butte MJ. Cytoskeletal adaptivity regulates T cell receptor signaling. Sci Signal. 2017 Mar 7;10(469):eaah3737. doi: 10.1126/scisignal.aah3737. PMID: 28270556; PMCID: PMC5854469.