Goswami Laboratory
Sangeeta Goswami, M.D., Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Goswami Laboratory
Areas of Research
- Immunology
- Immunotherapy
- Epigenetics
The Goswami Lab focuses on basic and translational studies investigating epigenetic pathways regulating responses and resistance to immune-based therapies. Our experimental approach is built upon a reverse translational strategy to explore the therapeutic vulnerabilities of epigenetic factors governing functional states of tumor and immune cell subsets. The overall goal of the lab is to develop a comprehensive understanding of epigenetic pathways that drive functional heterogeneity of immune cell subsets modulating therapeutic response or resistance to immune-based therapies and to evaluate potential biomarkers to stratify cancer patients into predictive categories to receive personalized immunotherapies and/or epigenetic modulators in a tumor-specific manner.
Our Research
We aim to develop strategies to target specific pathways to overcome primary and adaptive resistance to immune-based therapies.
We have identified critical epigenetic pathways that regulate functional phenotypes of T cells and myeloid cells that are currently being tested in the clinic.
Meet the Team
Lab Members
From left to right: Swadhin Meher, Aminah Tannir, Bidisha Chakraborty, Dr. Sangeeta Goswami, Dr. Pratishtha Singh, Dr. Sreyasi Das and Dr. Deblina Raychaudhuri
Join Our Lab
The Goswami Lab is recruiting a postdoctoral fellow. If interested, please apply using the link below.
News & Media
Our research has been featured internally and externally.