Publications
Ene CI, Abi Faraj C, Beckham TH, Weinberg JS, Andersen CR, Haider AS, Rao G, Ferguson SD,Alvarez-Brenkenridge CA, Kim BYS, Heimberger AB, McCutcheon IE, Prabhu SS, Wang CM, Ghia AJ, McGovern SL, Chung C, McAleer MF, Tom MC, Perni S, Swanson TA, Yeboa DN, Briere TM, Huse JT, Fuller GN, Lang FF, Li J, Suki D, Sawaya RE. Response of treatment-naive brain metastases to stereotactic radiosurgery. Nat Commun. 2024 May 2;15(1):3728. doi: 10.1038/s41467-024-47998-8. PubMed PMID: 38697991; PubMed Central PMCID: PMC11066027.
Ledbetter D, Gumin J, Phillips L, Ene C, Shimizu Y, Lang FF. Facilitating Repeat Intracarotid Injections in Mouse Models by a Novel Injection Site Repair Technique. J Vis Exp. 2024 Mar 15;(205). doi: 10.3791/66303. PubMed PMID: 38557500.
Shin DH, Jiang H, Gillard AG, Kim D, Fan X, Singh SK, Nguyen TT, Sohoni SS, Lopez-Rivas AR, Parthasarathy A, Ene CI, Gumin J, Lang FF, Alonso MM, Gomez-Manzano C, Fueyo J. Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice. Mol Ther. 2024 Mar 6;32(3):722-733. doi: 10.1016/j.ymthe.2024.01.035. Epub 2024 Feb 3. PubMed PMID: 38311852; PubMed Central PMCID: PMC10928285.
Noll KR, Asman P, Tasnim I, Hall M, Connelly K, Swamy C, Ene C, Tummala S, Grasu RM, Liu HL, Kumar VA, Muir M, Prinsloo S, Michener H, Wefel JS, Ince NF, Prabhu SS. Intraoperative language mapping guided by real-time visualization of gamma band modulation electrocorticograms: Case report and proof of concept. NeurooncolPract. 2024 Feb;11(1):92-100. doi: 10.1093/nop/npad059. eCollection 2024 Feb. PubMed PMID: 38222047; PubMed Central PMCID: PMC10785572.
Haider AS, McCutcheon IE, Ene CI, Fuller GN, Schomer DF, Gule-Monroe M, DeMonte F, Ferguson SD, Lang FF, Prabhu SS, Raza SM, Suki D, Weinberg JS, Sawaya R. Subependymomas of the fourth ventricle: To operate or not to operate? JClin Neurosci. 2023 Dec;118:147-152. doi: 10.1016/j.jocn.2023.10.025. Epub 2023 Nov 7. PMID: 37944358.
Haider AS, Ene CI, Palmisciano P, Haider M, Rao G, Ballester LY, Fuller GN. Concurrent IDH1 and IDH2 mutations in glioblastoma: A case report. Front Oncol. 2023 Apr 3;13:1071792. doi: 10.3389/fonc.2023.1071792. eCollection 2023. PMID: 37077830.
Muir M, Prinsloo S, Michener H, Shetty A, de Almeida Bastos DC, Traylor J, Ene C, Tummala S, Kumar VA, Prabhu SS. Transcranial magnetic stimulation (TMS) seeded tractography provides superior prediction of eloquence compared to anatomic seeded tractography. Neurooncol Adv. 2022 Sep 15;4(1):vdac126. doi: 10.1093/noajnl/vdac126. eCollection 2022 Jan-Dec. PMID: 36128584.
Hasanov E, Yeboa DN, Tucker MD, Swanson TA, Beckham TH, Rini B, Ene CI, Hasanov M, Derks S, Smits M, Dudani S, Heng DYC, Brastianos PK, Bex A, Hanalioglu S, Weinberg JS, Hirsch L, Carlo MI, Aizer A, Brown PD, Bilen MA, Chang EL, Jaboin J, Brugarolas J, Choueiri TK, Atkins MB, McGregor BA, Halasz LM, Patel TR, Soltys SG, McDermott DF, Elder JB, Baskaya MK, Yu JB, Timmerman R, Kim MM, Mut M, Markert J, Beal K, Tannir NM, Samandouras G, Lang FF, Giles R, Jonasch E. An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma. CA Cancer J Clin. 2022 Sep;72(5):454-489. doi: 10.3322/caac.21729. Epub 2022 Jun 16. PMID: 35708940.
Muir M, Prinsloo S, Traylor JI, Patel R, Ene C, Tummala S, Prabhu SS. Transcranial magnetic stimulation tractography and the facilitation of gross total resection in a patient with a motor eloquent glioblastoma: illustrative case. J Neurosurg Case Lessons. 2022 May 16;3(20):CASE22128. doi: 10.3171/CASE22128. Print 2022 May 16. PMID: 36303481.
Jiang B, Murray C, Cole BL, Glover JNM, Chan GK, Deschenes J, Mani RS, Subedi S, Nerva JD, Wang AC, Lockwood CM, Mefford HC, Leary SES, Ojemann JG, Weinfeld M, Ene CI. Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor. Sci Rep. 2022 Mar 30;12(1):5386. doi: 10.1038/s41598-022-09097-w. PMID: 35354845.
Ene CI, Ferguson SD. Surgical Management of Brain Metastasis: Challenges and Nuances. Front Oncol. 2022 Mar 14;12:847110. doi: 10.3389/fonc.2022.847110. eCollection 2022. PMID: 35359380.
Chen SR, Chen MM, Ene C, Lang FF, Kan P. Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of malignant brain tumors. J Neurointerv Surg. 2022 Jun;14(6):533-538. doi: 10.1136/neurintsurg-2021-018190. Epub 2021 Nov 25. PMID: 34824133.
Palmisciano P, Haider AS, Nwagwu CD, Wahood W, Yu K, Ene CI, O'Brien BJ, Aoun SG, Cohen-Gadol AA, El Ahmadieh TY. The Role of Immune Checkpoint Inhibitors in Leptomeningeal Disease: A Systematic Review. Anticancer Res. 2021 Nov;41(11):5333-5342. doi: 10.21873/anticanres.15346. PMID: 34732403.
Wang S, Sun MZ, Abecassis IJ, Weil AG, Ibrahim GM, Fallah A, Ene C, Leary SES, Cole BL, Lockwood CM, Olson JM, Geyer JR, Ellenbogen RG, Ojemann JG, Wang AC. Predictors of mortality and tumor recurrence in desmoplastic infantile ganglioglioma and astrocytoma — and individual participant data meta-analysis IPDMA). J Neurooncol. 2021 Nov;155(2):155-163. doi: 10.1007/s11060-021-03860-1. Epub 2021 Oct 6. PMID: 34613581.
Ene CI, Fueyo J, Lang FF. Delta-24 adenoviral therapy for glioblastoma: evolution from the bench to bedside and future considerations. Neurosurg Focus. 2021 Feb;50(2):E6. doi: 10.3171/2020.11.FOCUS20853. Review. PubMed PMID: 33524949.
Srinivasan VM, Ene C, Kerrigan BP, Lang FF. Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors. Neurosurg Clin N Am. 2021 Jan;32(1):93-104. doi: 10.1016/j.nec.2020.09.002. Epub 2020 Nov 5. Review. PubMed PMID: 33223031; PubMed Central PMCID: PMC7927773.
Brempelis KJ, Cowan CM, Kreuser SA, Labadie KP, Prieskorn BM, Lieberman NAP, Ene CI, Moyes KW, Chinn H, DeGolier KR, Matsumoto LR, Daniel SK, Yokoyama JK, Davis AD, Hoglund VJ, Smythe KS, Balcaitis SD, Jensen MC, Ellenbogen RG, Campbell JS, Pierce RH, Holland EC, Pillarisetty VG, Crane CA. Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses. J Immunother Cancer. 2020 Oct;8(2). doi: 10.1136/jitc-2020-001356. PubMed PMID: 33115946; PubMed Central PMCID: PMC7594542.
Ene CI, Kreuser SA, Jung M, Zhang H, Arora S, White Moyes K, Szulzewsky F, Barber J, Cimino PJ, Wirsching HG, Patel A, Kong P, Woodiwiss TR, Durfy SJ, Houghton AM, Pierce RH, Parney IF, Crane CA, Holland EC. Anti-PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma. Neuro Oncol. 2020 May 15;22(5):639-651. doi: 10.1093/neuonc/noz226. PubMed PMID: 31793634; PubMed Central PMCID: PMC7229244.
Zhang F, Stephan SB, Ene CI, Smith TT, Holland EC, Stephan MT. Nanoparticles That Reshape the Tumor Milieu Create a Therapeutic Window for Effective T-cell Therapy in Solid Malignancies. Cancer Res. 2018 Jul 1;78(13):3718-3730. doi: 10.1158/0008-5472.CAN-18-0306. Epub 2018 May 14. PubMed PMID: 29760047; PubMed Central PMCID: PMC6030470.
Ene CI, Edwards L, Riddick G, Baysan M, Woolard K, Kotliarova S, Lai C, Belova G, Cam M, Walling J, Zhou M, Stevenson H, Kim HS, Killian K, Veenstra T, Bailey R, Song H, Zhang W, Fine HA. Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization. PLoS One. 2012;7(12):e51407. doi: 10.1371/journal.pone.0051407. Epub 2012 Dec 7. PubMed PMID: 23236496; PubMed Central PMCID: PMC3517524.
Ene CI, Fine HA. Many tumors in one: a daunting therapeutic prospect. Cancer Cell. 2011 Dec 13;20(6):695-7. doi: 10.1016/j.ccr.2011.11.018. PubMed PMID: 22172718.
Edwards LA, Woolard K, Son MJ, Li A, Lee J, Ene C, Mantey SA, Maric D, Song H, Belova G, Jensen RT, Zhang W, Fine HA. Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion. J Natl Cancer Inst. 2011 Aug 3;103(15):1162-78. doi: 10.1093/jnci/djr224. Epub 2011 Jul 19. PubMed PMID: 21771732; PubMed Central PMCID: PMC3149042.