Dougherty Laboratory

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors

Tavares-Ferreira, et al., 2022, Sci Transl Med Opens a new window

Electrophysiological alterations driving pain-associated spontaneous activity in human sensory neuron somata parallel alterations described in spontaneously active rodent nociceptors

North et al., 2022, J Pain Opens a new window

Fadu head and neck squamous cell carcinoma induces hyperexcitability of primary sensory neurons in an in vitro coculture model

Uhelski et al., 2022, PAIN Reports Opens a new window

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain

Ray et al., 2022, Brain Opens a new window

Chemotherapy induced peripheral neuropathy in a dish: dorsal root ganglion cells treated in vitro with paclitaxel show biochemical and physiological responses parallel to that seen in vivo

Li et al., 2021, PAIN Opens a new window

Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons

North et al., 2019, Brain Opens a new window

DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain

Li et al., 2018, J Neurosci Opens a new window

Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy

Li et al., 2017, PAIN Opens a new window

Dorsal root ganglion infiltration by macrophages contributes to paclitaxel chemotherapy induced peripheral neuropathy

Zhang et al., 2016, J Pain Opens a new window

The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4

Li et al., 2015, J Neurosci Opens a new window