Publications
Di Pilato M*, Kfuri-Rubens R, Prüßmann JN, Ozga AJ, Messemaker M, Cadilha BL, Sivakumar R, Cianciaruso C, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala FP, Rheinbay E, Luster AD, Gerner MY, Kobold S, Pittet MJ, Mempel TR*. 2021. CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. Cell. *corresponding author
Marangoni F, Zhakyp A, Corsini M, Geels SN, Carrizosa E, Thelen M, Mani V, Prussmann JN, Warner RD, Ozga AJ, Di Pilato M, Othy S, Mempel TR. 2021. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell.
Cadilha BL, Benmebarek MR, Dorman K, Oner A, Lorenzini T, Obeck H, Vanttinen M, Di Pilato M, Pruessmann JN, Stoiber S, Huynh D, Markl F, Seifert M, Manske K, Suarez-Gosalvez J, Zeng Y, Lesch S, Karches CH, Heise C, Gottschlich A, Thomas M, Marr C, Zhang J, Pandey D, Feuchtinger T, Subklewe M, Mempel TR, Endres S, Kobold S. 2021. Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors. Science Advances.
Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grunmeier R, Seifert M, Oener A, Umut O, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, Konig LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S 2021. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nature Biomedical Engineering.
Di Pilato M*, Palomino-Segura M, Mejias-Perez E, Gomez CE, Rubio-Ponce A, D'Antuono R, Pizzagalli DU, Perez P, Kfuri-Rubens R, Benguria A, Dopazo A, Ballesteros I, Sorzano COS, Hidalgo A, Esteban M*, Gonzalez SF*. 2021. Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection. Nature Partner Journal Vaccines. *corresponding author
Perez P, Marin MQ, Lazaro-Frias A, Sorzano COS, Di Pilato M, Gomez CE, Esteban M, Garcia-Arriaza J. 2019. An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design. Vaccines.
Ligorio M, Sil S, Malagon-Lopez J, Nieman LT, Misale S, Di Pilato M, Ebright RY, Karabacak MN, Kulkarni AS, Liu A, Vincent Jordan N, Franses JW, Philipp J, Kreuzer J, Desai N, Arora KS, Rajurkar M, Horwitz E, Neyaz A, Tai E, Magnus NKC, Vo KD, Yashaswini CN, Marangoni F, Boukhali M, Fatherree JP, Damon LJ, Xega K, Desai R, Choz M, Bersani F, Langenbucher A, Thapar V, Morris R, Wellner UF, Schilling O, Lawrence MS, Liss AS, Rivera MN, Deshpande V, Benes CH, Maheswaran S, Haber DA, Fernandez-Del-Castillo C, Ferrone CR, Haas W, Aryee MJ, Ting DT. 2019. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell.
Di Pilato M*, Kim EY, Cadilha BL, Prussmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR*. 2019. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. *corresponding author
Usmani SM, Murooka TT, Deruaz M, Koh WH, Sharaf RR, Di Pilato M, Power KA, Lopez P, Hnatiuk R, Vrbanac VD, Tager AM, Allen TM, Luster AD, Mempel TR. 2019. HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. Cell Host & Microbe.
Di Pilato M*, Mejias-Perez E, Sorzano COS, Esteban M*. 2017. Distinct Roles of Vaccinia Virus NF-kappaB Inhibitor Proteins A52, B15, and K7 in the Immune Response. Journal of Virology. *corresponding author
Di Pilato M, Sanchez-Sampedro L, Mejias-Perez E, Sorzano COS, Esteban M. 2015. Modification of promoter spacer length in vaccinia virus as a strategy to control the antigen expression. Journal of General Virology.
Sanchez-Sampedro L, Perdiguero B, Mejias-Perez E, Garcia-Arriaza J, Di Pilato M, Esteban M. 2015. The evolution of poxvirus vaccines. Viruses.
Di Pilato M, Esteban M. 2015. Neutrophil and vaccine. Cell Cycle.
Di Pilato M, Mejias-Perez E, Zonca M, Perdiguero B, Gomez CE, Trakala M, Nieto J, Najera JL, Sorzano CO, Combadiere C, Pantaleo G, Planelles L, Esteban M. 2015. NFkappaB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses. Proc Natl Acad Sci U S A.
Daszkiewicz L, Vazquez-Mateo C, Rackov G, Ballesteros-Tato A, Weber K, Madrigal-Aviles A, Di Pilato M, Fotedar A, Fotedar R, Flores JM, Esteban M, Martinez AC, Balomenos D. 2015. Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-gamma production. Scientific Reports.
Di Pilato M, Mejias-Perez E, Gomez CE, Perdiguero B, Sorzano COS, Esteban M. 2013. New vaccinia virus promoter as a potential candidate for future vaccines. Journal of General Virology.
Perdiguero B, Gomez CE, Di Pilato M, Sorzano CO, Delaloye J, Roger T, Calandra T, Pantaleo G, Esteban M. 2013. Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C. PLoS One.