Di Pilato Laboratory

Our Research

By combining genetic mouse models and analyses of human cancer samples, the Di Pilato Laboratory wants to identify which key signals are necessary for intratumoral Treg destabilization and expansion in order to finally provide new individualized immunotherapy approaches to patients.

Our primary interests are understanding how tumor-associated neutrophils control regulatory T cell activation and effector T cell dysfunction and determining which chemokine are involved in their intratumoral accumulation and survival.