DePinho Laboratory
Ronald A. DePinho, M.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- DePinho Laboratory
Areas of Research
- Pancreatic Cancer
- Prostate Cancer
- Colorectal Cancer
- Glioblastoma
Our laboratory studies the molecular and biological processes governing the development of cancer, the basis for aging and degenerative diseases and the maintenance of normal and cancer stem cells. We have produced an array of discoveries leading to better methods of early cancer detection, improved cancer patient care and new cancer drug development. The range of our research includes cancer drug and biomarker development, cancer gene discovery, stem cell biology and development of genetically engineered mouse models to study human cancers.
Research in the DePinho Laboratory focuses on:
Cancer Biology
Tumor Microenvironment
Role of Telomerase in cancer and age-related diseases (e.g. neurodegeneration)
Genetically Engineered Mouse (GEM) Models
Approaches:
Comparative genomics
Mouse models of human cancer and age-related disease
Genetic screens
Bioinformatics and comparative analyses
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Research Areas
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