Publications
2021
NDRG1 in Aggressive Breast Cancer Progression and Brain Metastasis. Villodre, ES; Hu, X; Eckhardt, BL; Larson, R; Huo, L; Yoon, EC; Gong, Y; Song, J; Liu, S; Ueno, NT; Krishnamurthy, S; Pusch, S; Tripathy, D; Woodward, WA;. Debeb, BG. Journal of the National Cancer Institute, 2021; djab222, DOI: 10.1093/jnci/djab222
Inflammatory breast cancer appearance at presentation is associated with overall survival. Balema W, Liu D, Shen Y, El-Zein R, Debeb BG, Kai M, Overmoyer B, Miller KD, Le-Petross HT, Ueno NT, Woodward WA. Cancer Med. e-Pub 2021. PMCID: PMC8446552
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Villodre, ES; Hu, X; Larson, R; Finetti, P; Gomez, K; Balema, W; Stecklein, SR; Santiago-Sánchez, GS; Krishnamurthy, S; Song, J; Su, X; Ueno, NT; Tripathy, T; Van Laere, S; Bertucci, F; Vivas-Mejía, P; Woodward, WA; Debeb, BG. Molecular Oncology, 2021. PMCID: PMC8486564
Targeting Lipocalin-2 in inflammatory breast cancer cells with small interference RNA and small molecule inhibitors. Santiago-Sánchez, GS; Noriega-Rivera, R; Hernández-O’Farrill, E; Valiyeva, F; Quiñones-Diaz, B; Villodre, ES; Debeb, BG; Rosado-Albacarys, A; Vivas-Mejía, PE. International Journal of Molecular Sciences, 22, 8581, 2021. PMCID: PMC8395282
Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells. Hu, X*; Villodre, ES*; Woodward, WA; Debeb, BG. J. Vis. Exp., 168, e62249, 2021. DOI: 10.3791/62249
Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Fukumura, K; Malgulwar, PB; Fischer, GM; Hu, X; Mao, X; Song, X; Hernandez, SD; Zhang, XH; Zhang, J; Parra, ER; Yu, D; Debeb, BG; Davies, MA; Huse, JT. Acta Neuropathol 141(2):303-321, 2/2021. DOI: 10.1007/s00401-020-02256-1
Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer. Hu, X; Villodre, ES; Larson, R; Rahal, OM; Wang, X; Gong, Y; Song, J; Krishnamurthy, S; Ueno, NT; Tripathy, D; Woodward, WA; Debeb, BG. Communications Biology, 4, 72, 2021. PMCID: PMC7811004
Prophylactic cranial irradiation reduces the incidence of brain metastasis in a mouse model of metastatic, HER2-positive breast cancer. Smith DL, Debeb BG, Diagaradjane P, Larson R, Kumar S, Ning J, Lacerda L, Li L, Woodward WA. Genes Cancer 12:28-38, 2021. PMCID: PMC8045965
2020
NDRG1 expression is an independent prognostic factor in inflammatory breast cancer. Villodre, ES; Gong Y, Hu X, Huo L, Yoon EC, Ueno NT, Woodward WA, Tripathy D, Song J, Debeb BG. Cancers, 12, 3711, 2020. PMCID: PMC7763268
Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer. Gagliardi M, Pitner MK, Park J, Xie X, Saso H, Larson RA, Sammons RM, Chen H, Wei C, Masuda H, Chauhan G, Kondo K, Tripathy D, Ueno NT, Dalby KN, Debeb BG, Bartholomeusz C. Sci Rep 10(1):8537; 2020; PMCID: PMC7244517
NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers. Bertucci F, Rypens C, Finetti P, Guille A, Adélaïde J, Monneur A, Carbuccia N, Garnier S, Dirix P, Gonçalves A, Vermeulen P, Debeb BG, Wang X, Dirix L, Ueno NT, Viens P, Cristofanilli M, Chaffanet M, Birnbaum D, Van Laere S. Mol Oncol 14(3):504-519; 2020 PMCID: PMC7053236