Publications
Powell E, Shao J, Yuan Y, Chen HC, Cai S, Echeverria GV, Mistry N, Decker KF, Schlosberg C, Do KA, Edwards JR, Liang H, Piwnica-Worms D, Piwnica-Worms H. p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Res 18(1):13, 2016. e-Pub 1/2016. PMCID: PMC4728775.
Perera S, Piwnica-Worms D, Alauddin MM. Synthesis of a [(18) F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer. J Labelled Comp Radiopharm 59(3):103-8, 3/2016. e-Pub 2/2016. PMCID: PMC4863448.
Rosario M, Liu B, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA. The IL-15-Based ALT-803 Complex Enhances FcyRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas. Clin Cancer Res 22(3):596-608, 2/2016. e-Pub 9/2015. PMCID: PMC4738096.
Goiffon RJ, Martinez SC, Piwnica-Worms D. A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma. Nat Commun 6:6271, 2015. e-Pub 2/2015. PMCID: PMC4347050.
Tinkum KL, Stemler KM, White LS, Loza AJ, Jeter-Jones S, Michalski BM, Kuzmicki CE, Pless R, Stappenbeck TS, Piwnica-Worms D*, Piwnica-Worms H*. Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival. Proc Nat'l Acad Science USA 112(51):E7148-7154. e-Pub 12/2015. PMCID: PMC4697381.
Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi, A., Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF. [18F]FHBG PET/CT imaging of CD34-TK75 transduced donor T cells in relapsed allogeneic stem cell transplant patients: safety and feasibility. Mol Therapy 23(6):1110-1122, March 25, 2015, 6/2015. e-Pub 3/2015. PMID: 25807290.
Kocher BA, White LS, Piwnica-Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res 13(2):358-67, 2/2015. e-Pub 10/2014. PMCID: PMC4336824.
Sun L, Miyoshi H, Origanti S, Nice TJ, Barger AC, Manieri NA, Fogel LA, French AR, Piwnica-Worms D, Piwnica-Worms H, Virgin HW, Lenschow DJ, Stappenbeck TS. Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host Microbe 17(1):85-97, 1/2015.e-Pub 12/2014. PMCID: PMC4297260.
Qiu X, Johnson JR, Wilson BS, Gammon ST, Piwnica-Worms D, Barnett EM. Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe. PLoS One 9(2):e88855, 2014. e-Pub 2/2014. PMCID: PMC3931650.
Brooks MD, Jackson E, Warrington NM, Luo J, Forys JT, Taylor S, Mao DD, Leonard JR, Kim AH, Piwnica-Worms D, Mitra RD, Rubin JB. PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells. PLoS One 9(9):e107397, 2014. e-Pub 9/2014. PMCID: PMC4159344.
Garg G, Gibbs J, Belt B, Powell MA, Mutch DG, Goedegebuure P, Collins L, Piwnica-Worms D, Hawkins WG, Spitzer D. Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3. BMC Cancer 14(1):35, 2014. e-Pub 1/2014. PMCID: PMC3903436.
Garg G, Vangveravong S, Zeng C, Collins L, Hornick M, Hashim Y, Piwnica-Worms D, Powell MA, Mutch DG, Mach RH, Hawkins WG, Spitzer D. Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer. Mol Cancer 13:50, 2014. e-Pub 3/2014. PMCID: PMC4015918.
Sharma V, Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Piwnica-Worms D. A generator-produced Gallium-68 radiopharmaceutical for PET imaging of myocardial perfusion. PLoS One 9(10):e109361, 2014. e-Pub 10/2014. PMCID: PMC4212944.
Ippolito JE, Piwnica-Worms D. A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer. PLoS One 9(2):e88667, 2014. e-Pub 2/2014. PMCID: PMC3923810.
Eissenberg LG, Retting M, Dehdashti F, Piwnica-Worms D, DiPersio J. Suicide genes: monitoring cells in patients with a safety switch. Frontiers Pharmacol 5. e-Pub 11/2014.
Lee Y, Zacharias NM, Piwnica-Worms D, Bhattacharya PK. Chemical reaction-induced multi-molecular polarization (CRIMP). Chem Commun (Camb) 50(86):13030-3, 11/2014. PMID: 25224323.
Barone A, Sengupta R, Warrington NM, Smith E, Wen PY, Brekken RA, Romagnoli B, Douglas G, Chevalier E, Bauer MP, Dembowsky K, Piwnica-Worms D, Rubin JB. Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma. Oncotarget 5(20):9811-22, 10/2014. PMID: 25238146.
Nickless A, Jackson E, Marasa J, Nugent P, Mercer RW, Piwnica-Worms D, You Z. Intracellular calcium regulates nonsense-mediated mRNA decay. Nat Med 20(8):961-6, 8/2014. e-Pub 7/2014. PMCID: PMC4126864.
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 523(7559):177-182, June 24 2015, 7/2015. e-Pub 6/2015. PMID: 26106858.
Sengupta R, Barone A, Marasa J, Taylor S, Jackson E, Warrington NM, Rao S, Kim AH, Leonard JR, Piwnica-Worms D, Rubin JB. Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions. Oncotarget 6(21):18282-18292, July 30, 2015. e-Pub 7/2015. PMID: 26286961.