Publications

Whiting N, Hu J, Zacharias NM, Lokesh GL, Volk DE, Menter DG, Rupaimoole R, Previs R, Sood AK, Bhattacharya P. Developing hyperpolarized silicon particles for in vivo MRI targeting of ovarian cancer. J Med Imaging (Bellingham) 3(3):036001, 7/2016. e-Pub 8/2016. PMCID: PMC4979585.

Zacharias NM, McCullough CR, Wagner S, Sailasuta N, Chan HR, Lee Y, Hu J, Perman WH, Henneberg C, Ross BD, Bhattacharya P. Towards Real-time Metabolic Profiling of Cancer with Hyperpolarized Succinate. J Mol Imaging Dyn 6(1), doi:10.4172/2155-9937.1000123, 6/2016. e-Pub 1/2016. PMCID: PMC4989923.

Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK. Role of increased n-acetylaspartate levels in cancer. J Natl Cancer Inst 108(6):djv426, 1/2016. e-Pub 1/2016. PMCID: PMC4849357.

Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NM, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK. Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. Cell Rep 13(11):2395-402, 12/2015. e-Pub 12/2015. PMCID: PMC4691557.

Benito J, Ramirez MS, Millward NZ, Velez J, Harutyunyan KG, Lu H, Shi YX, Matre P, Jacamo R, Ma H, Konoplev S, McQueen T, Volgin A, Protopopova M, Mu H, Lee J, Bhattacharya PK, Marszalek JR, Davis RE, Bankson JA, Cortes JE, Hart CP, Andreeff M, Konopleva M. Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models. Clin Cancer Res 22(7):1687-98, 4/2016. e-Pub 11/2015. PMCID: PMC4818660.

Lai SY, Fuller CD, Bhattacharya PK, Frank SJ. Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors. Clin Cancer Res 21(22):4996-8, 11/2015. e-Pub 7/2015. PMCID: PMC4644683.

Whiting N, Hu J, Shah JV, Cassidy MC, Cressman E, Millward NZ, Menter DG, Marcus CM, Bhattacharya PK. Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles. Sci Rep 5:12842, 2015. e-Pub 8/2015. PMCID: PMC4523869.

Lee Y, Zacharias N, Piwnica-Worms D, Bhattacharya PK. Chemical Reaction-Induced Multi-molecular Polarization (CRIMP). Chemical Communications 50 50(86):13030-3, 11/2014. PMCID: PMC4369324.

Cassidy MC, Chan HR, Ross BD, Bhattacharya PK, Marcus CM. In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat Nanotechnol 8(5):363-8, May, 5/2013. e-Pub 5/2013. PMID: 23644571.

Lingwood MD, Siaw TA, Sailasuta N, Abulseoud OA, Chan HR, Ross BD, Bhattacharya PK, Han S. Hyperpolarized Water as an MR Imaging Contrast Agent: Feasibility of in Vivo Imaging in a Rat Model. Radiology 265(2):418-425, 2012. PMCID: PMC3480810.

Zacharias NM, Chan HR, Sailasuta N, Ross BD, Bhattacharya PK. Real-Time Molecular Imaging of Tricarboxylic Acid Cycle Metabolism. Journal of the American Chemical Society 134(2):934-943, 2012. PMCID: PMC3262122.

Bhattacharya PK, Chekmenev E, Reynolds WF, Wagner S, Zacharias N, Chan HR, Bunger R, Ross BD. PHIP Hyperpolarized MR Receptor Imaging In Vivo: A Pilot Study of 13C Imaging of Atheroma in Mice. NMR in Biomedicine 24(Special Issue Research Article):1023-1028, 2/2011. PMCID: PMC3240663.

Ross B, Tran T, Bhattacharya PK, Watterson DM, Sailasuta N. Application of NMR Spectroscopy in Medicinal Chemistry and Drug Discovery. Current Topics in Medicinal Chemistry 11(1):93-114, 2011. PMID: 20809893.

Lingwood MD, Siaw TA, Sailasuta N, Ross BD, Bhattacharya PK, Han S. Continuous flow Overhauser dynamic nuclear polarization of water in the fringe field of a clinical magnetic resonance imaging system for authentic image contrast. J Magn Reson 205(2):247-254, 8/2010. e-Pub 5/2010. PMID: 20541445.

Ross BD, Bhattacharya PK, Wagner S, Tran T, Sailasuta N. Hyperpolarized MR imaging: neurologic applications of hyperpolarized metabolism. AJNR Am J Neuroradiol 31(1):24-33, 1/2010. e-Pub 10/2009. PMID: 19875468.

Perman WH, Bhattacharya PK, Leupold J, Lin AP, Harris KC, Norton VA, Hovener JB, Ross BD. Fast volumetric spatial-spectral MR imaging of hyperpolarized 13C-labeled compounds using multiple echo 3D bSSFP. Magnetic Resonance Imaging 28(4):459-465, 2010. PMCID: PMC2860036.

Bhattacharya PK, Ross BD, Bünger R. Cardiovascular Applications of Hyperpolarized Contrast Media and Metabolic Tracers. Exp Biol Med (Maywood) 234(12):1395-1416, 12/2009. PMID: 19934362.

Chekmenev EY, Norton VA, Weitekamp DP, Bhattacharya PK. Hyperpolarized 1H NMR Employing Low γ Nucleus for Spin Polarization Storage. J Am Chem Soc 131(9):3164-3165, 2/2009. PMCID: PMC2662390.

Hovener JB, Chekmenev EY, Harris KC, Perman WH, Robertson LW, Ross BD, Bhattacharya PK. PASADENA Hyperpolarization of 13C Biomolecules: Equipment Design and Installation. MAGMA-Magnetic Resonance Materials in Physics, Biology and Medicine 22(2):111-121, 2009. PMCID: PMC2664858.

Hovener J-B, Chekmenev EY, Harris KC, Perman WH, Tran TT, Ross BD, Bhattacharya PK. Quality assurance of PASADENA hyperpolarization for. MAGMA-Magnetic Resonance Materials in Physics, Biology and Medicine 22(2):123-134, 2009. PMCID: PMC2664864.

Chekmenev EY, Hövener J, Norton VA, Harris K, Batchelder LS, Bhattacharya PK, Ross BD, Weitekamp DP. PASADENA hyperpolarization of succinic acid for MRI and NMR spectroscopy. J Am Chem Soc 130(13):4212-3, 4/2008. e-Pub 3/2008. PMCID: PMC2662769.

Chekmenev EY, Chow S-K, Tofan D, Weitekamp DP, Ross BD, Bhattacharya PK. Fluorine-19 NMR Chemical Shift Probes Molecular Binding to Lipid Membranes. The Journal of Physical Chemistry B 112(20):6285-6287, 2008. PMCID: PMC2663341.

Bhattacharya PK, Chekmenev EY, Harris KC, Perman WH, Li AP, Norton VA, Chow CT, Ross BD, Weitekamp DP. Towards Hyperpolarized (13)C-succinate Imaging of Brain Cancer. J Magn Reson 186(1):150-155, 1/2007. PMCID: PMC2657725.

Bhattcharya PK, Harris K, Lin AP, Mansson M, Norton VA, Perman WH, Weitekamp DP, Ross BD. Ultra-fast Three Dimensional Imaging of Hyperpolarized 13C In Vivo. Biology and Medicine Magnetic Resonance Materials in Physics 18(5):245-256, 11/2005.

Bhattacharya PK, Lawson HJ, Barton JK. 1H NMR Studies of Nickel(II) Complexes Bound to Oligonucleotides: A Novel Technique for Distinguishing the Binding Locations of Metal Complexes in DNA. Inorg Chem 42(26):8811-8817, 12/2003. PMID: 14686861.

Ross B, Lin A, Harris K, Bhattacharya PK, Schweinsburg B. Clinical experience with 13C MRS in vivo. NMR in Biomedicine 16(6-7):358-369, 2003. PMID: 14679500.

Bhattacharya PK, Cha J, Barton JK. 1H NMR determination of base-pair lifetimes in oligonucleotides containing single base mismatches. Nucleic Acids Res 30(21):4740-50, 11/2002. PMCID: PMC135820.

Delaney S, Pascaly M, Bhattacharya PK, Han K, Barton JK. Oxidative damage by ruthenium complexes containing the dipyridophenazine ligand or its derivatives: a focus on intercalation. Inorg Chem 41(7):1966-74, 4/2002. PMID: 11925195.

Bhattacharya PK, Barton JK. Influence of Intervening Mismatches on Long-Range Guanine Oxidation in DNA Duplexes. J Am Chem Soc 123(36):8649-8656, 9/2001. PMID: 11535068.