Bhattacharya Laboratory
Pratip Bhattacharya, Ph.D.
Principal Investigator
Cancer Systems Imaging
Associate Professor
Areas of Research
- Imaging
The main focus of my laboratory is on the development of Magnetic Resonance (MR) and MR-based hyperpolarization techniques and metabolic and molecular imaging probes that can enhance the sensitivity of the current in vivo MR methodologies for disease diagnosis, particularly in areas of cancer and cardiovascular diseases.
Over the past eight years, my laboratory has worked on the development of different modalities of hyperpolarization like Parahydrogen Induced Polarization (PHIP), Dynamic Nuclear Polarization (DNP), Continuous Flow DNP of water and solid state DNP processes of Silicon nanoparticles as well as developed applications in various types of cancer, cardiovascular diseases and tobacco-related diseases. My laboratory has developed hyperpolarized imaging probes like succinic acid, diethyl succinate and tetrafluoropropylprionate (TFPP) that can interrogate metabolic pathways in real time in vivo as well act as molecular imaging probes of atherosclerotic plaque in rodent models. I enjoy close collaboration with physician/scientists, radiologists, oncologists, and basic cancer researchers to explore new opportunities and identify critical needs to ensure that imaging science advances alongside novel therapeutic approaches to improve the next generation of clinical care.
I believe that imaging plays an important role in fundamental cancer research, optimization of new therapies and, ultimately, the quality of care and outcome for those touched by cancer.
Grants
Functional Imaging and Prostate Cancer
Funding Source: MDACC Philanthropy, Koch Functional Imaging and Prostate Cancer Project
Role: Co-Principal Investigator
Duration: 10/1/2015 - 9/30/2017
Non-invasive Colonoscopy by Molecular Imaging of Mucin Targeted Hyperpolarized Silicon Nanoparticles
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Principal Investigator
Duration: 9/1/2015 - 8/31/2017
Early assessment of ovarian cancer aggressiveness and therapeutic efficacy by real-time hyperpolarized metabolic imaging
Funding Source: Institutional Research Grant Program (IRG)
Role: Principal Investigator
Duration: 9/1/2015 - 8/31/2016
Hyperpolarized Metabolic Imaging of Brain Cancer Therapy to Predict Outcome
Funding Source: NCI SPORE
Role: Principal Investigator
Duration: 9/1/2015 - 8/31/2016
Brain Tumor SPORE Development Research Project
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 9/1/2015 - 8/31/2016
Non-invasive Assessment of Ovarian Cancer Aggressiveness Using Real-time Hyperpolarized Metabolic Imaging
Funding Source: Sprint for Life Research Award
Role: Principal Investigator
Duration: 6/1/2015 - 5/31/2016
Inhibiting Oxidative Phosphorylation: A Novel Strategy in Leukemia
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Co-Investigator
Principal Investigator: Konopleva
Duration: 9/1/2014 - 8/31/2017
Therapeutic Targeting of Glioblastoma
Funding Source: MD Anderson Brain Tumor Moonshot Award
Role: Co-Investigator
Duration: 9/1/2014 - 8/31/2016
Early Detection of Pancreatic Cancer In Vivo by Molecular Imaging of Lactose-functionalized Silicon Nanoparticles and Hyperpolarized Magnetic Resonance
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 4/1/2014 - 3/31/2016
Prostate Cancer Research Program Idea (PCRP-DoD)
Funding Source: DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP)
Role: Co-Investigator
Principal Investigator: Zacharias-Millward, Niki
Duration: 9/30/2012 - 9/29/2016
Institutional Startup Research Funding
Funding Source: The University of Texas MD Anderson Cancer Center Cancer System Imaging Department
Role: Principal Investigator-MDACC
Principal Investigator: Pratip Bhattacharya
Duration: 4/1/2012 - 3/30/2017
Related Links
Contact
The University of Texas MD Anderson Cancer Center
Cancer Systems Imaging
1881 East Road
Unit Number: 1907
Houston, TX 77054-1901
Room Number: 3SCR4.3634
Phone: 713-745-0769
Fax: 713-794-5456
Email: PKBhattacharya@mdanderson.org