Allison Laboratory
James P. Allison, Ph.D.
Principal Investigator
Areas of Research
- Immunology
- Immunotherapy
- Melanoma
- Pancreatic Cancer
- Chemotherapy
- Radiation Therapy
- Prostate Cancer
- Epigenetics
- Targeted Therapy
The Allison Lab researches the fundamental mechanisms of T cell activation and regulation through cell surface receptors of the T cells and the antigen presenting cells with which they interact. The lab also investigates the mechanisms through which alterations in cell surface receptor signaling affect the cancer immune response.
Allison awarded Nobel Prize
Congratulations to our own Jim Allison, Ph.D., who was awarded the 2018 Nobel Prize in Physiology or Medicine for his pioneering work in immunotherapy.
Learn more about his groundbreaking workOur Research
Work in the Allison lab takes advantage of the latest technology, including CyTOF and single-cell profiling as well as spatial profiling of immune cells, and collaborations with some of the world’s finest clinical oncologists at MD Anderson. The end goal of work in my lab is to provide knowledge of the immune system that serves to guide the next generation of immunotherapy, including synergistic combinations of immunotherapy with other treatment modalities to make this the last generation to know the devastation of cancer.
Meet the Team
Allison Lab, 2023, from left to right, Kenny Dao, James Mancuso, Naveen Sharma, Jim Allison, Stephen Mok, Didem Cobanoglu, Mehdi Chaib, Huey Liu
not shown: Mashid Arabi and Ying Hu