Peer Reviewed Publications

2024

Kumar B, Singh A, Basar R, Uprety N, Li Y, Fan H, Cortes AKN, Kaplan M, Acharya S, Shaim H, Xu AC, Wu M, Ensley E, Fang D, Banerjee PP, Garcia LM, Tiberti S, Lin P, Rafei H, Munir MN, Moore M, Shanley M, Mendt M, Kerbauy LN, Liu B, Biederstädt A, Gokdemir E, Ghosh S, Kundu K, Reyes-Silva F, Jiang XR, Wan X, Gilbert AL, Dede M, Mohanty V, Dou J, Zhang P, Liu E, Muniz-Feliciano L, Deyter GM, Jain AK, Rodriguez-Sevilla JJ, Colla S, Garcia-Manero G, Shpall EJ, Chen K, Abbas HA, Rai K, Rezvani K, Daher M. BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Sci Transl Med. 2024 Sep 11;16(764):eadp0004. doi: 10.1126/scitranslmed.adp0004. Epub 2024 Sep 11. PMID: 39259809.

Cuglievan B, Kantarjian H, Rubnitz JE, Cooper TM, Zwaan CM, Pollard JA, DiNardo CD, Kadia TM, Guest E, Short NJ, McCall D, Daver N, Nunez C, Haddad FG, Garcia M, Bhalla KN, Maiti A, Catueno S, Fiskus W, Carter BZ, Gibson A, Roth M, Khazal S, Tewari P, Abbas HA, Bourgeois W, Andreeff M, Shukla NN, Truong DD, Connors J, Ludwig JA, Stutterheim J, Salzer E, Juul-Dam KL, Sasaki K, Mahadeo KM, Tasian SK, Borthakur G, Dickson S, Jain N, Jabbour E, Meshinchi S, Garcia-Manero G, Ravandi F, Stein EM, Kolb EA, Issa GC. Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community. Leukemia. 2024 Aug 23. doi: 10.1038/s41375-024-02368-7. Epub ahead of print. PMID: 39179671.

Marvin-Peek J, Sasaki K, Kontoyiannis DP, Adachi J, Ohanian M, Takahashi K, Issa GC, Kornblau S, Abbas HA. Nontuberculosis mycobacteria (NTM) infections in patients with leukemia: a single center case series. Front Med (Lausanne). 2024 Aug 1;11:1402897. doi: 10.3389/fmed.2024.1402897. PMID: 39149601; PMCID: PMC11324579.

Chomczyk M, Gazzola L, Dash S, Firmanty P, George BS, Mohanty V, Abbas HA, Baran N. Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment. Front Pharmacol. 2024 Aug 5;15:1409210. doi: 10.3389/fphar.2024.1409210. PMID: 39161899; PMCID: PMC11330794.

Haddad FG, Sasaki K, Senapati J, Xiao L, Park G, Abuasab T, Venugopal S, Rivera D, Bazinet A, Babakhanlou R, Kim K, Ong F, Desikan S, Pemmaraju N, Loghavi S, Borthakur G, DiNardo C, Abbas HA, Short NJ, Daver N, Jabbour E, Garcia-Manero G, Ravandi F, Kantarjian H, Kadia T. Outcomes of Patients With Newly Diagnosed AML and Hyperleukocytosis. JCO Oncol Pract. 2024 Jul 16:OP2400027. doi: 10.1200/OP.24.00027. Epub ahead of print. PMID: 39013130.

Radpour R, Simillion C, Wang B, Abbas HA, Riether C, Ochsenbein AF. IL-9 Secreted by Leukemia Stem Cells Induces Th1-Skewed CD4+ T-Cells, which Promote Their Expansion. Blood, 6/2024. PMID: 38941612.

Kadia TM, Huang M, Pemmaraju N, Abbas HA, Ly C, Masarova L, Yilmaz M, Lyu MA, Zeng K, Sadeghi T, Cook R, DiNardo CD, Daver N, Issa GC, Jabbour E, Borthakur G, Jain N, Garcia-Manero G, Parmar S, Flowers C, Kantarjian H, Verstovsek S. Phase 1 Study of CK0801 in Treatment of Bone Marrow Failure Syndromes. NEJM Evid 3(6):EVIDoa2300362, 6/2024. e-Pub 5/2024. PMID: 38804782.

Narayanan N, Marvin-Peek J, Abouelnaaj MK, Majid D, Wang B, Brown BD, Qiu Y, Kornblau SM, Abbas HA. Reverse Phase Proteomic Array Profiling of Asparagine Synthetase Expression in Newly Diagnosed Acute Myeloid Leukemia. J Proteome Res. e-Pub 6/2024. PMID: 38829961.

Wang B, Reville PK, Yassouf MY, Jelloul FZ, Ly C, Desai PN, Wang Z, Borges P, Veletic I, Dasdemir E, Burks JK, Tang G, Guo S, Garza AI, Nasnas C, Vaughn NR, Baran N, Deng Q, Matthews J, Gunaratne PH, Antunes DA, Ekmekcioglu S, Sasaki K, Garcia MB, Cuglievan B, Hao D, Daver N, Green MR, Konopleva M, Futreal A, Post SM, Abbas HA. Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies. Nat Commun. 2024 Feb 28;15(1):1821. doi: 10.1038/s41467-024-45916-6. PMID: 38418901; PMCID: PMC10902356.

Root JL, Desai PN, Ly C, Wang B, Jelloul FZ, Zhou J, Mackay S, Alfayez M, Matthews J, Pierce S, Reville PK, Daver N, Abbas HA. Single-Cell CD4 and CD8 T-Cell Secretome Profiling Reveals Temporal and Niche Differences in Acute Myeloid Leukemia Following Immune Checkpoint Blockade Therapy. Cancer Res Commun. 2024 Mar 6;4(3):671-681. doi: 10.1158/2767-9764.CRC-23-0402. PMID: 38391202; PMCID: PMC10916538.

Guo S, Mohan GS, Wang B, Li T, Daver N, Zhao Y, Reville PK, Hao D, Abbas HA. Paired single-B-cell transcriptomics and receptor sequencing reveal activation states and clonal signatures that characterize B cells in acute myeloid leukemia. J Immunother Cancer. 2024 Feb 28;12(2):e008318. doi: 10.1136/jitc-2023-008318. PMID: 38418394; PMCID: PMC10910691.

2023

Senapati J, Urrutia S, Loghavi S, Short NJ, Issa GC, Maiti A, Abbas HA, Daver NG, Pemmaraju N, Pierce S, Chien KS, Sasaki K, Kadia TM, Hammond DE, Borthakur G, Patel K, Ravandi F, Kantarjian HM, Garcia-Manero G, DiNardo CD. Venetoclax abrogates the prognostic impact of splicing factor gene mutations in newly diagnosed acute myeloid leukemia. Blood. 2023 Nov 9;142(19):1647-1657. doi: 10.1182/blood.2023020649. PubMed PMID: 37441846.

Bazinet A, Kantarjian H, Arani N, Popat U, Bataller A, Sasaki K, DiNardo CD, Daver N, Yilmaz M, Abbas HA, Short NJ, Issa G, Jabbour E, Pierce SA, Chen J, Garcia R, Konopleva M, Garcia-Manero G, Alousi A, Shpall EJ, Champlin RE, Borthakur G, Ravandi F, Kadia T. Evolving trends and outcomes in older patients with acute myeloid leukemia including allogeneic stem cell transplantation. Am J Hematol. 2023 Sep;98(9):1383-1393. doi: 10.1002/ajh.26997. Epub 2023 Jun 19. PubMed PMID: 37334870.

Fan H, Wang F, Zeng A, Murison A, Tomczak K, Hao D, Jelloul FZ, Wang B, Barrodia P, Liang S, Chen K, Wang L, Zhao Z, Rai K, Jain AK, Dick J, Daver N, Futreal A, Abbas HA. Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance. Commun Biol. 2023 Jul 21;6(1):765. doi: 10.1038/s42003-023-05120-6. PubMed PMID: 37479893; PubMed Central PMCID: PMC10362028.

Senapati J, Muftuoglu M, Ishizawa J, Abbas HA, Loghavi S, Borthakur G, Yilmaz M, Issa GC, Dara SI, Basyal M, Li L, Naqvi K, Pourebrahim R, Jabbour EJ, Kornblau SM, Short NJ, Pemmaraju N, Garcia-Manero G, Ravandi F, Khoury J, Daver N, Kantarjian HM, Andreeff M, DiNardo CD.A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis. Blood Cancer J. 2023 Jun 29;13(1):101. doi: 10.1038/s41408-023-00871-1. PubMed PMID: 37386016; PubMed Central PMCID: PMC10310786.

Desai PN, Wang B, Fonseca A, Borges P, Jelloul FZ, Reville PK, Lee E, Ly C, Basi A, Root J, Baran N, Post SM, Deng Q, Sun H, Harmanci AO, Burks JK, Gomez JA, DiNardo CD, Daver NG, Alatrash G, Konopleva M, Green MR, Antunes DA, Futreal A, Hao D, Abbas HA. Single-Cell Profiling of CD8+ T Cells in Acute Myeloid Leukemia Reveals a Continuous Spectrum of Differentiation and Clonal Hyperexpansion. Cancer Immunol Res. 2023 Jun 7;OF1-OF18. doi:
.10.1158/2326-6066.CIR-22-0961.  PubMed PMID: 37285177.

Chu Y, Dai E, Li Y, Han G, Pei G, Ingram DR, Thakkar K, Qin JJ, Dang M, Le X, Hu C, Deng Q, Sinjab A, Gupta P, Wang R, Hao D, Peng F, Yan X, Liu Y, Song S, Zhang S, Heymach JV, Reuben A, Elamin YY, Pizzi MP, Lu Y, Lazcano R, Hu J, Li M, Curran M, Futreal A, Maitra A, Jazaeri AA, Ajani JA, Swanton C, Cheng XD, Abbas HA, Gillison M, Bhat K, Lazar AJ, Green M, Litchfield K, Kadara H, Yee C, Wang L. Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance. Nat Med. 2023 Jun;29(6):1550-1562. doi: 10.1038/s41591-023-02371-y. Epub 2023 May 29. PubMed PMID: 37248301.

Beird HC, Yin CC, Khoury JD, Pierce SR, Abbas HA, Zhao L, Skwarska A, Qazilbash MH, Konopleva MY, Futreal A, Pemmaraju N. TET2 truncating mutations predict a worse outcome in blastic plasmacytoid dendritic cell neoplasm. Blood Adv. 2023 May 23;7(10):2000-2003. doi: 10.1182/bloodadvances.2022007879. PubMed PMID: 36689729; PubMed Central PMCID: PMC10188632.

Lee SE, Wang F, Grefe M, Trujillo-Ocampo A, Ruiz-Vasquez W, Takahashi K, Abbas HA, Borges P, Antunes DA, Al-Atrash G, Daver N, Molldrem JJ, Futreal A, Garcia-Manero G, Im JS. Immunologic Predictors for Clinical Responses during Immune Checkpoint Blockade in Patients with Myelodysplastic Syndromes. Clin Cancer Res. 2023 May 15;29(10):1938-1951. doi: 10.1158/1078-0432.CCR-22-2601. PubMed PMID: 36988276; PubMed Central PMCID: PMC10192218.

Abbas HA, Sun H, Pierce S, Kanagal-Shamanna R, Li Z, Yilmaz M, Borthakur G, DiPippo AJ, Jabbour E, Konopleva M, Short NJ, DiNardo C, Daver N, Ravandi F, Kadia TM. Validation of Acute Leukemia French Association ALFA1200 model in older patients with AML treated with intensive chemotherapy. Blood Adv. 2023 Mar 14;7(5):828-831. doi: 10.1182/bloodadvances.2022007172. PubMed PMID: 35405739; PubMed Central PMCID: PMC9996355.

Reddy DR, Cuenca JA, Botdorf J, Muthu M, Hanmandlu A, Wegner R, Crommett J, Gutierrez C, Rathi N, Sajith B, Knafl M, Abbas HA, Woodman SE, Nates JL, D3CODE Team Collaborators. Clinical Characteristics and Cause of Death Among Hospitalized Decedents With Cancer and COVID-19. Mayo Clin Proc. 2023 Mar;98(3):451-457. doi: 10.1016/j.mayocp.2022.12.008. Epub 2022 Dec 28. PubMed PMID: 36868753; PubMed Central PMCID: PMC9794478.

2022

Abbas HA, Ayoub E, Sun H, Kanagal-Shamanna R, Short NJ, Issa G, Yilmaz M, Pierce S, Rivera D, Cham B, Wing S, Li Z, Hammond D, Jabbour E, Borthakur G, Garcia-Manero G, Andreeff M, Daver N, Kadia T, Konopleva M, DiNardo C, Ravandi F. Clinical and molecular profiling of AML patients with chromosome 7 or 7q deletions in the context of TP53 alterations and venetoclax treatment. Leuk Lymphoma. 2022 Dec;63(13):3105-3116. doi: 10.1080/10428194.2022.2118533. Epub 2022 Sep 10. PubMed PMID: 36089905; PubMed Central PMCID: PMC9772202.

Rutella S, Vadakekolathu J, Mazziotta F, Reeder S, Yau TO, Mukhopadhyay R, Dickins B, Altmann H, Kramer M, Knaus HA, Blazar BR, Radojcic V, Zeidner JF, Arruda A, Wang B, Abbas HA, Minden MD, Tasian SK, Bornhäuser M, Gojo I, Luznik L. Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia. J Clin Invest. 2022 Nov 1;132(21). doi: 10.1172/JCI159579. PubMed PMID: 36099049; PubMed Central PMCID: PMC9621145.

Short NJ, Macaron W, Kadia T, Dinardo C, Issa GC, Daver N, Wang S, Jorgensen J, Nguyen D, Bidikian A, Patel KP, Loghavi S, Konopleva M, Yilmaz M, Jabbour E, Maiti A, Abbas HA, Shpall E, Popat U, Al-Atrash G, Pierce S, Kantarjian HM, Ravandi F. Clinical outcomes and impact of therapeutic intervention in patients with acute myeloid leukemia who experience MRD recurrence following MRD-negative remission. Am J Hematol. 2022 Nov;97(11):E408-E411. doi: 10.1002/ajh.26698. Epub 2022 Sep 8. PubMed PMID: 36054774.

Lachowiez CA, Reville PK, Kantarjian H, Jabbour E, Borthakur G, Daver N, Issa G, Furudate K, Tanaka T, Pierce S, Tang G, Patel KP, Medeiros J, Abbas HA, Haddad F, Hammond D, Short NJ, Maiti A, Yilmaz M, Sasaki K, Takahashi K, Pemmaraju N, Konopleva M, Garcia-Manero G, Ravandi F, Kadia TM, Loghavi S, DiNardo CD. Contemporary outcomes in IDH-mutated AML: The impact of co-occurring NPM1 mutations and venetoclax-based treatment. Am J Hematol. 2022 Nov;97(11):1443-1452. doi: 10.1002/ajh.26694. Epub 2022 Sep 15. PubMed PMID: 36054614.

Venugopal S, Borthakur G, Daver N, DiNardo CD, Pemmaraju N, Short NJ, Abbas HA, Garcia-Manero G, Konopleva M, Ravandi F, Kadia TM. Validation of ALFA 1200 score in patients with AML >60 years treated with double nucleoside-based low-intensity therapy. Blood Adv. 2022 Oct 11;6(19):5546-5549. doi: 10.1182/bloodadvances.2021006689. PubMed PMID: 35201293; PubMed Central PMCID: PMC9647734.

Zeng AGX, Bansal S, Jin L, Mitchell A, Chen WC, Abbas HA, Chan-Seng-Yue M, Voisin V, van Galen P, Tierens A, Cheok M, Preudhomme C, Dombret H, Daver N, Futreal PA, Minden MD, Kennedy JA, Wang JCY, Dick JE. A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia. Nat Med. 2022 Jun;28(6):1212-1223. doi: 10.1038/s41591-022-01819-x. Epub 2022 May 26. PubMed PMID: 35618837.

Pabon CM, Abbas HA, Konopleva M. Acute myeloid leukemia: therapeutic targeting of stem cells. Expert Opin Ther Targets. 2022 Jun;26(6):547-556. doi: 10.1080/14728222.2022.2083957. Epub 2022 Jun 2. Review. PubMed PMID: 35634856.

Short NJ, Macaron W, Konopleva M, Ravandi F, Jain N, Issa GC, Kadia T, Sasaki K, Kebriaei P, Yilmaz M, Thompson PA, Takahashi K, Abbas HA, Wierda WG, Garris R, Kantarjian HM, Jabbour E. Dismal outcomes of patients with relapsed/refractory Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia after failure of both inotuzumab ozogamicin and blinatumomab. Am J Hematol. 2022 Jun 1;97(6):E201-E204. doi: 10.1002/ajh.26526. Epub 2022 Mar 17. PubMed PMID: 35266566.

Napoli M, Wu SJ, Gore BL, Abbas HA, Lee K, Checker R, Dhar S, Rajapakshe K, Tan AC, Lee MG, Coarfa C, Flores ER. ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer. Nat Commun. 2022 Feb 1;13(1):614. doi: 10.1038/s41467-022-28202-1. PubMed PMID: 35105868; PubMed Central PMCID: PMC8807845.

2021

Tang M*, Abbas HA*, Negrao MV, Ramineni M, Hu X, Hubert SM, Fujimoto J, Reuben A, Varghese S, Zhang J, Li J, Chow CW, Mao X, Song X, Lee WC, Wu J, Little L, Gumbs C, Behrens C, Moran C, Weissferdt A, Lee JJ, Sepesi B, Swisher S, Cheng C, Kurie J, Gibbons D, Heymach JV, Wistuba II, Futreal PA, Kalhor N, Zhang J. The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics. Nat Commun.2021 Dec 6;12(1):7081. doi: 10.1038/s41467-021-27341-1. PubMed PMID: 34873156; PubMed Central PMCID: PMC8648877. *co-first

Abbas HA, Reville PK, Geppner A, Rausch CR, Pemmaraju N, Ohanian M, Sasaki K, Borthakur G, Daver N, DiNardo C, Bueso-Ramos C, Pierce S, Jabbour E, Garcia-Manero G, Konopleva M, Ravandi F, Kantarjian H, Kadia TM. Clinical and molecular characterization of myeloid sarcoma without medullary leukemia. Leuk Lymphoma. 2021 Dec;62(14):3402-3410. doi: 10.1080/10428194.2021.1961235. Epub 2021 Aug 12. PubMed PMID: 34380367; PubMed Central PMCID: PMC8939853.

Abbas HA, Alaniz Z, Mackay S, Cyr M, Zhou J, Issa GC, Alfayez M, Matthews J, Kornblau SM, Jabbour E, Garcia-Manero G, Konopleva M, Andreeff M, Daver N. Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy. Blood Adv. 2021 Nov 23;5(22):4569-4574. doi: 10.1182/bloodadvances.2021004583. PubMed PMID: 34555853; PubMed Central PMCID: PMC8759127.

Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F, Al-Atrash G, Takahashi K, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S, Konopleva M, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A, Garcia-Manero G, Green MR, Sharma P, Allison JP, Kornblau SM, Rai K, Wang L, Daver N, Futreal A. Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy. Nat Commun. 2021 Oct 18;12(1):6071. doi: 10.1038/s41467-021-26282-z. PubMed PMID: 34663807; PubMed Central PMCID: PMC8524723.

Wilson NR, Abbas HA, Kala J. Paroxysmal Nocturnal Hemoglobinuria Presenting with Hemorrhagic Esophageal Varices. Am J Med. 2021 Mar;134(3):e147-e149. doi: 10.1016/j.amjmed.2020.09.026. Epub 2020 Oct 26. PubMed PMID: 33121958.

Abbas HA, Mohanty V, Wang R, Huang Y, Liang S, Wang F, Zhang J, Qiu Y, Hu CW, Qutub AA, Dail M, Bolen CR, Daver N, Konopleva M, Futreal A, Chen K, Wang L, Kornblau SM. Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes. Front Oncol. 2021;11:705627. doi: 10.3389/fonc.2021.705627. eCollection 2021. PubMed PMID: 34422660; PubMed Central PMCID: PMC8372368.

Abbas HA, Reville PK, Jiang X, Yang H, Reuben A, Im JS, Little L, Sinson JC, Chen K, Futreal A, Garcia-Manero G. Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes. Front Immunol. 2021;12:659625. doi: 10.3389/fimmu.2021.659625. eCollection 2021. PubMed PMID: 33912187; PubMed Central PMCID: PMC8072464.

Abbas HA, Wierda WG. Acalabrutinib: A Selective Bruton Tyrosine Kinase Inhibitor for the Treatment of B-Cell Malignancies. Front Oncol. 2021;11:668162. doi: 10.3389/fonc.2021.668162. eCollection 2021. Review. PubMed PMID: 34055635; PubMed Central PMCID: PMC8162209.

2020

Bui NHB, Napoli M, Davis AJ, Abbas HA, Rajapakshe K, Coarfa C, Flores ER. Spatiotemporal Regulation of ΔNp63 by TGFβ-Regulated miRNAs Is Essential for Cancer Metastasis. Cancer Res. 2020 Jul 1;80(13):2833-2847. doi: 10.1158/0008-5472.CAN-19-2733. Epub 2020 Apr 20. PubMed PMID: 32312834; PubMed Central PMCID: PMC7385751.

Davis AJ, Tsinkevich M, Rodencal J, Abbas HA, Su XH, Gi YJ, Fang B, Rajapakshe K, Coarfa C, Gunaratne PH, Koomen JM, Tsai KY, Flores ER. TAp63-Regulated miRNAs Suppress Cutaneous Squamous Cell Carcinoma through Inhibition of a Network of Cell-Cycle Genes. Cancer Res. 2020 Jun 15;80(12):2484-2497. doi: 10.1158/0008-5472.CAN-19-1892. Epub 2020 Mar 10. PubMed PMID: 32156775; PubMed Central PMCID: PMC7299759.

Abbas HA, Amini B, Wang WL, Ravi V. Maneuvering the Management of a Rare Case of Primary Undifferentiated Cardiac Sarcoma. Am J Case Rep. 2020 Mar 21;21:e918878. doi: 10.12659/AJCR.918878. PubMed PMID: 32198341; PubMed Central PMCID: PMC7117855.

Zhuo M, Guan Y, Yang X, Hong L, Wang Y, Li Z, Chen R, Abbas HA, Chang L, Gong Y, Wu N, Zhong J, Chen W, Chen H, Dong Z, Zhu X, Li J, Wang Y, An T, Wu M, Wang Z, Wang J, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Lee JJ, Heymach JV, Wistuba II, Kalhor N, Yang L, Yi X, Futreal PA, Glisson BS, Xia X, Zhang J, Zhao J. The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma. Clin Cancer Res. 2020 Feb 15;26(4):892-901. doi: 10.1158/1078-0432.CCR-19-0556. Epub 2019 Nov 6. PubMed PMID: 31694833; PubMed Central PMCID: PMC7024651.

2019

Hoff FW, Hu CW, Qutub AA, Qiu Y, Hornbaker MJ, Bueso-Ramos C, Abbas HA, Post SM, de Bont ESJM, Kornblau SM. Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse. Proteomics Clin Appl. 2019 Jul;13(4):e1800133. doi: 10.1002/prca.201800133. Epub 2019 Feb 4. PubMed PMID: 30650251; PubMed Central PMCID: PMC6635093.

Abbas HA, Ravandi F, Loghavi S, Patel KP, Borthakur G, Kadia TM, Jabbour E, Takahashi K, Cortes J, Issa GC, Konopleva M, Kantarjian HM, Short NJ. NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia. Am J Hematol. 2019 Jun;94(6):E158-E160. doi: 10.1002/ajh.25454. Epub 2019 Mar 18. PubMed PMID: 30838674; PubMed Central PMCID: PMC6602057.

Abbas HA, Han X. Cytoplasmic Blebs in T-Cell Prolymphocytic Leukemia. N Engl J Med. 2019 Jun 13;380(24):2360. doi: 10.1056/NEJMicm1814629. PubMed PMID: 31189039.

Abbas HA, Alfayez M, Kadia T, Ravandi-Kashani F, Daver N. Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection. Cancer Manag Res. 2019;11:8817-8828. doi: 10.2147/CMAR.S177894. eCollection 2019. PubMed PMID: 31632141; PubMed Central PMCID: PMC6782026.

Zhao L, Zhang J, Xu L, Abbas HA. Novel Cancer Immunotherapies and Antitumor Immunity. J Immunol Res. 2019;2019:3742061. doi: 10.1155/2019/3742061. eCollection 2019. PubMed PMID: 31428655; PubMed Central PMCID: PMC6679854.

2018

Rafei RE, Abbas HA, Alameddine H, Bizri AA, Melki I, Yunis KA. Assessing the Risk of Having Small for Gestational Age Newborns Among Lebanese Underweight and Normal Pre-pregnancy Weight Women. Matern Child Health J. 2018 Jan;22(1):130-136. doi: 10.1007/s10995-017-2362-4. PubMed PMID: 28780682.

Abbas HA, Bui NHB, Rajapakshe K, Wong J, Gunaratne P, Tsai KY, Coarfa C, Flores ER. Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes. Cancer Res. 2018 Jan 15;78(2):451-462. doi: 10.1158/0008-5472.CAN-17-1803. Epub 2017 Nov 27. PubMed PMID: 29180475; PubMed Central PMCID: PMC5771893.

2017

Abiad F, Awwad J, Abbas HA, Zebian D, Ghazeeri G. Management of weight loss in obesity-associated male infertility: a spotlight on bariatric surgery. Hum Fertil (Camb). 2017 Dec;20(4):227-235. doi: 10.1080/14647273.2017.1317369. Epub 2017 May 2. Review. PubMed PMID: 28460579.

Ezzeddine D, Ezzeddine D, Hamadi C, Abbas HA, Nassar A, Abiad M, Ghazeeri G. Prevalence and Correlation of Hypothyroidism With Pregnancy Outcomes Among Lebanese Women. J Endocr Soc. 2017 May 1;1(5):415-422. doi: 10.1210/js.2017-00014. eCollection 2017 May 1. PubMed PMID: 29264496; PubMed Central PMCID: PMC5686637.

Su X, Napoli M, Abbas HA, Venkatanarayan A, Bui NHB, Coarfa C, Gi YJ, Kittrell F, Gunaratne PH, Medina D, Rosen JM, Behbod F, Flores ER. TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway. Oncogene. 2017 Apr 27;36(17):2377-2393. doi: 10.1038/onc.2016.388. Epub 2016 Nov 21. PubMed PMID: 27869165; PubMed Central PMCID: PMC5415945.

Inati A, Mansour AG, Sabbouh T, Amhez G, Hachem A, Abbas HA. Transfusion Therapy in Children With Sickle Cell Disease. J Pediatr Hematol Oncol. 2017 Mar;39(2):126-132. doi: 10.1097/MPH.0000000000000645. Review. PubMed PMID: 27509379.

Inati A, Kahale M, Sbeiti N, Cappellini MD, Taher AT, Koussa S, Nasr TA, Musallam KM, Abbas HA, Porter JB. One-year results from a prospective randomized trial comparing phlebotomy with deferasirox for the treatment of iron overload in pediatric patients with thalassemia major following curative stem cell transplantation. Pediatr Blood Cancer. 2017 Jan;64(1):188-196. doi: 10.1002/pbc.26213. Epub 2016 Aug 31. PubMed PMID: 27576370.

2016

Chitsazzadeh V, Coarfa C, Drummond JA, Nguyen T, Joseph A, Chilukuri S, Charpiot E, Adelmann CH, Ching G, Nguyen TN, Nicholas C, Thomas VD, Migden M, MacFarlane D, Thompson E, Shen J, Takata Y, McNiece K, Polansky MA, Abbas HA, Rajapakshe K, Gower A, Spira A, Covington KR, Xiao W, Gunaratne P, Pickering C, Frederick M, Myers JN, Shen L, Yao H, Su X, Rapini RP, Wheeler DA, Hawk ET, Flores ER, Tsai KY. Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates. Nat Commun. 2016 Aug 30;7:12601. doi: 10.1038/ncomms12601. PubMed PMID: 27574101; PubMed Central PMCID: PMC5013636.

Ghazeeri G, Zebian D, Nassar AH, Harajly S, Abdallah A, Hakimian S, Skaiff B, Abbas HA, Awwad J. Knowledge, attitudes and awareness regarding fertility preservation among oncologists and clinical practitioners in Lebanon. Hum Fertil (Camb). 2016 Jun;19(2):127-33. doi: 10.1080/14647273.2016.1193636. Epub 2016 Jul 4. PubMed PMID: 27376977.

Napoli M, Venkatanarayan A, Raulji P, Meyers BA, Norton W, Mangala LS, Sood AK, Rodriguez-Aguayo C, Lopez-Berestein G, Vin H, Duvic M, Tetzlaff MB, Curry JL, Rook AH, Abbas HA, Coarfa C, Gunaratne PH, Tsai KY, Flores ER. ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer. Cancer Cell. 2016 Jun 13;29(6):874-888. doi: 10.1016/j.ccell.2016.04.016. PubMed PMID: 27300436; PubMed Central PMCID: PMC4908836.

Inati A, El Hachem Y, Tawk S, Kassm SA, Abbas HA. Pediatric Immune Thrombocytopenia in Lebanon: Treatment and Predictors of Outcome. Pediatr Blood Cancer. 2016 Feb;63(2):375-6. doi: 10.1002/pbc.25732. Epub 2015 Aug 27. PubMed PMID: 26313008.

Batley NJ, Nasreddine Z, Chami A, Zebian D, Bachir R, Abbas HA. Cynicism and other attitudes towards patients in an emergency department in a middle eastern tertiary care center. BMC Med Educ. 2016 Jan 29;16:36. doi: 10.1186/s12909-016-0539-y. PubMed PMID: 26823070; PubMed Central PMCID: PMC4731937.

El Rafei R, Abbas HA, Charafeddine L, Nakad P, Al Bizri A, Hamod D, Yunis KA. Association of Pre-Pregnancy Body Mass Index and Gestational Weight Gain with Preterm Births and Fetal Size: an Observational Study from Lebanon. Paediatr Perinat Epidemiol. 2016 Jan;30(1):38-45. doi: 10.1111/ppe.12249. Epub 2015 Oct 15. PubMed PMID: 26469281.

2015 and earlier

Ghazeeri G, Abbas HA, Skaff B, Harajly S, Awwad J. Inadequacy of initiating rosuvastatin then metformin on biochemical profile of polycystic ovarian syndrome patients. J Endocrinol Invest. 2015 Jun;38(6):643-51. doi: 10.1007/s40618-015-0237-3. Epub 2015 Feb 27. PubMed PMID: 25722221.

Inati A, Noureldine MA, Mansour A, Abbas HA. Endocrine and bone complications in β-thalassemia intermedia: current understanding and treatment. Biomed Res Int. 2015;2015:813098. doi: 10.1155/2015/813098. Epub 2015 Mar 5. Review. PubMed PMID: 25834825; PubMed Central PMCID: PMC4365366.

Jiang S, Minter LC, Stratton SA, Yang P, Abbas HA, Akdemir ZC, Pant V, Post S, Gagea M, Lee RG, Lozano G, Barton MC. TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice. J Hepatol. 2015 Feb;62(2):371-9. doi: 10.1016/j.jhep.2014.09.026. Epub 2014 Oct 2. PubMed PMID: 25281858; PubMed Central PMCID: PMC4772153.

Inati A, Noun P, Kabbara N, Salloum C, Kmeid M, Sadek M, Abbas HA, Kahale M. A multicenter study on the Lebanese experience with hereditary spherocytosis. Pediatr Blood Cancer. 2014 Oct;61(10):1895-6. doi: 10.1002/pbc.24992. Epub 2014 Mar 4. PubMed PMID: 24590699.

Khoriaty E, Halaby R, Berro M, Sweid A, Abbas HA, Inati A. Incidence of sickle cell disease and other hemoglobin variants in 10,095 Lebanese neonates. PLoS One. 2014;9(9):e105109. doi: 10.1371/journal.pone.0105109. eCollection 2014. PubMed PMID: 25180595; PubMed Central PMCID: PMC4152148.

Abbas HA, Yunis K. The effect of consanguinity on neonatal outcomes and health. Hum Hered. 2014;77(1-4):87-92. doi: 10.1159/000362125. Epub 2014 Jul 29. Review. PubMed PMID: 25060272.

Inati A, Kahale M, Perrine SP, Chui DH, Taher AT, Koussa S, Abi Nasr T, Abbas HA, Ghalie RG. A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in β-thalassaemia intermedia. Br J Haematol. 2014 Feb;164(3):456-8. doi: 10.1111/bjh.12635. Epub 2013 Nov 13. PubMed PMID: 24224649; PubMed Central PMCID: PMC3904791.

Inati A, Abbas HA, Korjian S, Daaboul Y, Harajeily M, Saab R. A case of Pitt-Hopkins syndrome with absence of hyperventilation. J Child Neurol. 2013 Dec;28(12):1698-701. doi: 10.1177/0883073812468054. Epub 2012 Dec 17. PubMed PMID: 23248353.

Inati A, Tourjuman O, Bizri D, Dhayni R, Abbas HA, Tfaili H, Akouri G, Beydoun A. A rare case of Moyamoya syndrome in a β-thalassemia major patient. Blood Cells Mol Dis. 2013 Oct;51(3):149-50. doi: 10.1016/j.bcmd.2013.05.005. Epub 2013 Jun 2. PubMed PMID: 23735661.

Ghazeeri G, Fakih A, Abbas HA, Harajly S, Awwad J. Anxiety, cognitive, and depressive assessment in adolescents with polycystic ovarian syndrome: a pilot study. J Pediatr Adolesc Gynecol. 2013 Oct;26(5):269-73. doi: 10.1016/j.jpag.2013.04.005. Epub 2013 Jul 10. PubMed PMID: 23849090.

Pant V, Xiong S, Jackson JG, Post SM, Abbas H, Quintás-Cardama A, Hamir AN, Lozano G. The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity. Genes Dev. 2013 Sep 1;27(17):1857-67. doi: 10.1101/gad.227249.113. Epub 2013 Aug 23. PubMed PMID: 23973961; PubMed Central PMCID: PMC3778240.

Abbas HA, Kahale M, Hosn MA, Inati A. A review of acute chest syndrome in pediatric sickle cell disease. Pediatr Ann. 2013 Mar;42(3):115-20. doi: 10.3928/00904481-20130222-11. Review. PubMed PMID: 23458871.

Salman M, Khoury NJ, Khalifeh I, Abbas HA, Majdalani M, Abboud M, Muwakkit S, Solh HE, Saab R. Congenital infantile fibrosarcoma: Association with bleeding diathesis. Am J Case Rep. 2013;14:481-5. doi: 10.12659/AJCR.889489. eCollection 2013. PubMed PMID: 24265847; PubMed Central PMCID: PMC3835170.

Inati A, Akouri G, Abbas HA. A rare aggravation of severe mucositis post chemotherapy in a child with acute lymphoblastic leukemia. F1000Res. 2013;2:196. doi: 10.12688/f1000research.2-196.v1. eCollection 2013. PubMed PMID: 24555093; PubMed Central PMCID: PMC3790598.

Inati A, Abbas HA, Al-Danaf J, Souaid M, Kahale M, Koussa S, Abou Nasr T, Davis L, Luo HY, Chui DH. Identification of the first mutation in a BRE motif of the β-globin gene and its inheritance with two other α-globin gene mutations in a Lebanese family. Hemoglobin. 2013;37(2):171-5. doi: 10.3109/03630269.2013.772523. PubMed PMID: 23470150.

Abbas HA, Saab R. Premalignancy and Cellular Senescence. In: Tumor Dormancy, Quiescence, and Senescence, Volume 2. 2. Ed(s) MA Hayat. Springer, 195-206, 2013. PMID: 978-94-007-7726-2.

Inati A, Abbas HA, Boumitri C, Tecle N. Prevalence of glucose-6-phosphate dehydrogenase deficiency among neonates at a tertiary care centre in Lebanon. J Med Screen. 2012 Jun;19(2):103-4. doi: 10.1258/jms.2012.011138. Epub 2012 May 3. PubMed PMID: 22554801.

Abbas HA, Pant V, Lozano G. The ups and downs of p53 regulation in hematopoietic stem cells. Cell Cycle. 2011 Oct 1;10(19):3257-62. doi: 10.4161/cc.10.19.17721. Epub 2011 Oct 1. PubMed PMID: 21957490; PubMed Central PMCID: PMC3233622.

Abbas HA, Houri AF. In: Student's Guide to Graduate School, First. Self Publish, 2011. PMID: 978-9953-0-2204-8.

Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G. Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell. 2010 Nov 5;7(5):606-17. doi: 10.1016/j.stem.2010.09.013. PubMed PMID: 21040902; PubMed Central PMCID: PMC3026610.

Post SM, Pant V, Abbas H, Quintás-Cardama A. Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma. Oncotarget. 2010 Jul;1(3):168-74. doi: 10.18632/oncotarget.100712. Review. PubMed PMID: 21301048; PubMed Central PMCID: PMC3157715.