MDASI Hepatectomy Perioperative Symptoms Module
The MD Anderson Symptom Inventory for measuring perioperative symptoms in patients undergoing hepatectomy for liver malignancy (MDASI-PERIOP-HEP) is a disease- and treatment-specific MDASI module. Use the MDASI-PERIOP-HEP to assess the severity of symptoms experienced by patients undergoing hepatectomy for liver cancer and the interference with daily living caused by these symptoms.
Along with the core MDASI’s 13 symptom items and 6 interference items, the MDASI-PERIOP-HEP also assesses 5 symptoms relevant to hepatectomy perioperative care.
| Core MDASI Symptoms | Hepatectomy Perioperative Symptoms | MDASI Interference |
|---|---|---|
| Pain | Incisional tightness | Relations with other people |
| Fatigue | Constipation | Enjoyment of life |
| Nausea | Muscle weakness, instability, or vertigo | Mood |
| Disturbed sleep | Abdominal cramping | Walking |
| Distress (feeling upset) | Abdominal boating, tightness, or fullness | Activity |
| Shortness of breath | Work (including housework) | |
| Difficulty remembering | ||
| Lack of appetite | ||
| Drowsiness | ||
| Dry mouth | ||
| Sadness | ||
| Vomiting | ||
| Numbness/tingling |
Order the MDASI-PERIOP-HEP
Use our convenient online form to order the MDASI-PERIOP-HEP for use in your clinical research, clinical practice, funded and non-funded academic research, commercial research, or reproduction in educational materials or other publications.
MDASI-PERIOP-HEP Features
- Purpose: To assess the severity of multiple perioperative symptoms in patients undergoing hepatectomy for liver malignancy and the impact of these symptoms on daily functioning
- Population: Patients with symptoms caused by hepatectomy for liver malignancy
- Assessment areas: Severity of multiple symptoms and the impact of symptoms on daily functioning during the last 24 hours
- Method: Self-report or interview with research staff; paper-and-pencil or electronic data entry*
- Time required: Five minutes or less
- Scoring: Please see the MDASI User Guide
- Reliability: Cronbach alpha reliability ranges from 0.86 to 0.90
*Electronic data capture offers several benefits:
- Allows symptom monitoring when the patient is away from the hospital
- Is convenient for patients, who can choose web access, personalized patient portals, or smartphones to access questionnaires
- Minimizes missing data, especially in longitudinal studies
- Provides accurate, real-time symptom data at expected time points
- Generates immediate feedback, potentially allowing caregivers to address severe symptoms more effectively
MDASI-PERIOP-HEP Language Versions
Click on a linked language to view a sample in PDF format.
Don't see a language you need? Contact us at symptomresearch@mdanderson.org.
| Psychometrically and Linguistically Validated | Linguistically Validated |
|---|---|
| English |
MDASI User Guide
In response to the US Food and Drug Administration's 2009 guidance for the pharmaceutical industry on the use of patient-reported outcomes measures in medical product development to support labeling claims, we have prepared a MDASI User Guide to document the development and psychometric properties of the MDASI and its modules. The User Guide addresses the recommendations in the FDA guidance and establishes the MDASI's adequacy as a measure to support medical product claims.
Selected MDASI-PERIOP-HEP References
Validation
Wang XS, Shi Q, Williams LA, et al. Development of a patient-reported outcome tool for assessing symptom burden during perioperative care in liver surgery: the MDASI-PeriOp-Hep. Eur J Oncol Nurs 52:101959, 2021.
Cleeland CS, Mendoza TR, Wang XS, et al. Assessing symptom distress in cancer: the M. D. Anderson Symptom Inventory. Cancer 89:1634-1646, 2000.
Clinical Application
Zhang X, Zhang H, Zhang Z, et al. The mediating effect of resilience on the relationship between symptom burden and anxiety/depression among Chinese patients with primary liver cancer after liver resection. Patient Prefer Adherence 17:3033-3043, 2023.
Lillemoe HA, Marcus RK, Kim BJ, et al. Severe preoperative symptoms delay readiness to Return to Intended Oncologic Therapy (RIOT) after liver resection. Ann Surg Oncol 26(13):4548-4555, 2019.
Every MDASI module contains:
all 13 core MDASI symptoms...
pain, fatigue, nausea, disturbed sleep, distress, shortness of breath, difficulty remembering, lack of appetite, drowsiness, dry mouth, sadness, vomiting, numbness/tingling
...and all 6 MDASI interference items
general activity, mood, work, relations with others, walking, enjoyment of life
The MDASI-PERIOP-HEP is a valid, reliable, concise tool for measuring symptom severity and functional interference in patients undergoing liver surgery. Having a procedure-specific tool like the MDASI-PERIOP-HEP is desirable when integrating patient-reported outcomes in perioperative patient care.
Vijaya Gottumukkala, M.D.
Professor, Anesthesiology & Perioperative Medicine