MDASI Esophageal Cancer/Radiotherapy Module
The MD Anderson Symptom Inventory for esophageal cancer (MDASI-ESO) is a disease- and treatment-specific MDASI module. Use the MDASI-ESO to assess the severity of symptoms experienced by patients undergoing radiation therapy for esophageal cancer and the interference with daily living caused by these symptoms.
Along with the core MDASI’s 13 symptom items and 6 interference items, the MDASI-ESO also assesses 8 symptoms relevant to esophageal cancer treated with radiotherapy.
| Core MDASI Symptoms | Esophageal Cancer with Radiotherapy Symptoms | MDASI Interference |
|---|---|---|
| Pain | Difficulty swallowing | Relations with other people |
| Fatigue | Weakness | Enjoyment of life |
| Nausea | Inability to eat | Mood |
| Disturbed sleep | Constipation | Walking |
| Distress (feeling upset) | Regurgitation (acid reflux) | Activity |
| Shortness of breath | Sore mouth or throat | Work (including housework) |
| Difficulty remembering | Diarrhea | |
| Lack of appetite | Hoarseness or voice changes | |
| Drowsiness | ||
| Dry mouth | ||
| Sadness | ||
| Vomiting | ||
| Numbness/tingling |
Order the MDASI-ESO
Use our convenient online form to order the MDASI-ESO for use in your clinical research, clinical practice, funded and non-funded academic research, commercial research, or reproduction in educational materials or other publications.
MDASI-ESO Features
- Purpose: To assess the severity of multiple symptoms related to esophageal cancer treated with radiation therapy and the impact of these symptoms on daily functioning
- Population: Patients with symptoms caused by esophageal cancer and its treatment with radiotherapy
- Assessment areas: Severity of multiple symptoms and the impact of symptoms on daily functioning during the last 24 hours
- Method: Self-report or interview with research staff; paper-and-pencil or electronic data entry*
- Time required: Five minutes or less
- Scoring: Please see the MDASI User Guide
- Reliability: Psychometric validation is in process
*Electronic data capture offers several benefits:
- Allows symptom monitoring when the patient is away from the hospital
- Is convenient for patients, who can choose web access, personalized patient portals, or smartphones to access questionnaires
- Minimizes missing data, especially in longitudinal studies
- Provides accurate, real-time symptom data at expected time points
- Generates immediate feedback, potentially allowing caregivers to address severe symptoms more effectively
MDASI-ESO Language Versions
Click on a linked language to view a sample in PDF format.
Don't see a language you need? Contact us at symptomresearch@mdanderson.org.
| Psychometrically and Linguistically Validated | Linguistically Validated |
|---|---|
| Chinese (Simplified) | |
| English |
MDASI User Guide
In response to the US Food and Drug Administration's 2009 guidance for the pharmaceutical industry on the use of patient-reported outcomes measures in medical product development to support labeling claims, we have prepared a MDASI User Guide to document the development and psychometric properties of the MDASI and its modules. The User Guide addresses the recommendations in the FDA guidance and establishes the MDASI's adequacy as a measure to support medical product claims.
Selected MDASI-ESO References
Validation
Shi Q, Williams L, Garcia Gonzalez A, et al. A qualitative study for identifying radiation therapy related symptom burden in patients with esophageal cancer: MDASI-Eso development [abstract]. Int J Radiat Onc Biol Phys 102(3 Suppl):E733, 2018.
Cleeland CS, Mendoza TR, Wang XS, et al. Assessing symptom distress in cancer: the M. D. Anderson Symptom Inventory. Cancer 89:1634-1646, 2000.
Every MDASI module contains:
all 13 core MDASI symptoms...
pain, fatigue, nausea, disturbed sleep, distress, shortness of breath, difficulty remembering, lack of appetite, drowsiness, dry mouth, sadness, vomiting, numbness/tingling
...and all 6 MDASI interference items
general activity, mood, work, relations with others, walking, enjoyment of life
The MDASI-ESO is designed to assess conventional radiotherapy outcomes in patients with esophageal cancer and outcomes from newer treatments, such as proton therapy. Once validated, the MDASI-ESO will be useful for routine monitoring and symptom assessment in this patient group.
Xin Shelley Wang, M.D., M.P.H.
Professor, Symptom Research