Cancer-associated fibroblasts fuel breast cancer growth
Researchers at MD Anderson have discovered that cancer-associated fibroblasts (CAF) help fuel the growth of breast tumors. Their findings were published in Cell Reports on June 2, and an image from their study was featured on the cover of the journal issue.
Raghu Kalluri, M.D., Ph.D., professor and chair of Cancer Biology and senior author for this study, explains, “Tumors are made of many more non-cancer cells than cancer cells...
Ovarian cancer analysis identifies potential treatment biomarkers
MD Anderson researchers have identified potential biomarkers for the response of high-grade serous ovarian cancers (HGSC) to surgical resection...
Tumor cells form networks to penetrate the brain
Researchers from MD Anderson have revealed how glioma cells move and infiltrate the brain, providing a new potential treatment pathway to explore against these deadly brain tumors.
“Glioma is not usually resectable or curable because it spreads diffusely throughout the brain, like mold in bread. We found that glioma cells form a moving network, and we’ve identified a novel mechanism that could be targeted to halt that cellular...
JAMA study reveals side effect impact of localized prostate cancer treatments
A study published in JAMA comparing adverse event outcomes by treatment type for patients with localized prostate cancer reveals most...
Metastatic cells, mechanisms of drug resistance identified for triple-negative breast cancer
Researchers at The University of Texas MD Anderson Cancer Center have discovered important mechanisms of drug resistance and metastasis in...
Mutations in tumor-adjacent tissues could reveal earliest events leading to malignancy
MD Anderson researchers have identified early genomic events that may lead to malignant transformation. They’ve found that tissue adjacent...
Study identifies novel therapeutic approach for head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer globally. Even with multimodality treatment, including surgery...
Inducible immune resistance to protect lungs earns prestigious support
Immunology research to investigate the mechanisms of a new aerosol treatment, which induces an innate immune response to protect against pathogens...
Shielding healthy organs from radiotherapy for pancreatic cancer
Unresectable pancreatic cancer is usually fatal because other treatments, such as radiation therapy, cannot be used. Radiation therapy causes...