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To learn if MGD019 can help to control cervical cancer in patients who have yet to receive treatment.
This phase IIA trial studies the effect of a vaccine (PDS0101) when given together with chemotherapy and radiation therapy (chemoradiation) in treating patients with stage IB3-IVA cervical cancer. Chemotherapy drugs, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. PDS0101 is a type of vaccine that is intended to help the immune system respond to human papillomavirus (HPV16)-infected cervical tumor cells. PDS0101 contains two active components: the first is called R-DOTAP (Versamune) and is included in the vaccine to boost the immune system's response against the HPV viral proteins and the second group of active components are selected small pieces of proteins (called peptides) taken from the HPV virus. Giving PDS0101 in combination with chemoradiation may work help to control cervical cancer.
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...
The research group on adaptive image-guided radiotherapy for locally advanced cervical carcinoma completed the protocol for the EMBRACE II study in October 2018. This study will be carried out in the next few years at the University Clinic for Radiotherapy at the Medical University of Vienna and other international partner institutes. EMBRACE II builds on the findings of the current EMBRACE study. These are already implemented in everyday clinical practice in order to further improve the accuracy of the entire therapy of cervical carcinomas, using state-of-the-art techniques of tele- and brachytherapy. The aim of the EMBRACE II study is to maintain and enhance the excellent local tumor control as well as the nodal and systemic control for all tumor stages while minimizing the adverse reaction rates for all affected organs (rectum, sigmoid, urinary bladder, and vagina) to increase the quality of life of patients with cervical carcinomas.
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...
and Testing FAQs Cancer Screenings Cancer Screenings Cancer Screenings Home Mammograms & Breast Cancer Screening Cervical Cancer Screening Colorectal Cancer Screening Endometrial Cancer Screening Liver Cancer Screening Lung Cancer Screening Mobile Mammography Ovarian Cancer Screening Prostate Cancer Screening Skin Cancer Screening Women's Cancer Screening Men's Cancer Screening Cancer Prevention Center The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening...