Study #COGAHEP1531
COGAHEP1531: Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT) A Phase 2/3 Study An Intergroup Study by Societe Internationale d'Oncologie Pediatrique (SIOPEL) in collaboration with COG and the Japanese Children's Cancer Group (JCCG) Co
MD Anderson Study Status
Not Accepting
Treatment Agent
Cisplatin, Doxorubicin, Fluorouracil, Vincristine Sulfate, Carboplatin, Etoposide, Irinotecan, Sorafenib, Gemcitabine, Oxaliplatin
Description
This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving combination chemotherapy may kill more tumor cells than one type of chemotherapy alone.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Childhood Hepatocellular Carcinoma, Childhood Malignant Liver Neoplasm, Fibrolamellar Carcinoma, Hepatoblastoma, Hepatocellular Malignant Neoplasm, Not Otherwise Specified
Study phase:
Phase III
Physician name:
Najat Daw Bitar
Department:
Pediatrics
For general questions about clinical trials:
1-877-632-6789
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