Study #2024-0442
A multicenter, open-label, phase 1 study of AJ1-11095 administered as oral monotherapy in patients with primary myelofibrosis (pmf), post-polycythemia vera myelofibrosis (PPV-MF), or post-essential thrombocythemia myelofibrosis (PET-MF) who have been failed by a Type I JAK2 Inhibitor (JAK2i)
MD Anderson Study Status
Enrolling
Treatment Agent
AJ1-11095
Description
AJX-101 is a first-in-human (FIH), phase 1, non-randomized, multi-center, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics (PK), clinical activity and changes in biomarkers of an orally administered type II JAK2 inhibitor, AJ1-11095, in subjects with primary or secondary myelofibrosis previously treated with at least one type I JAK2 inhibitor.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Primary Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, PMF, PPV-MF, PET-MF
Study phase:
Phase I
Physician name:
Prithviraj Bose
Department:
Leukemia
For general questions about clinical trials:
1-833-471-0966
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