Study #2023-1034
A phase 1b/2a multi-center, dose escalation and reference regimen-controlled, multi-cohort study to determine the safety and efficacy of oral 7HP349 (Alintegimod) in combination with Ipilimumab followed by Nivolumab Monotherapy in patients with locally advanced or metastatic cancers following one or more prior therapies
MD Anderson Study Status
Enrolling
Treatment Agent
Alintegimod, Ipilimumab, Nivolumab
Description
This study is an open-label Phase Ib (Part A) dose escalation followed by a blinded, randomized, multi cohort Phase 2a (Part B) comparison of combination vs. reference regimens. Currently study will only be enrolling the Phase 1b and the Phase 2a protocol requirements will be added to the study near completion of the Phase 1b
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis, Pleural Mesothelioma, Renal Cell Carcinoma, MSI-High, Mismatch Repair Deficiency, Colorectal Cancer, Hepatocellular Carcinoma, Hepatocellular Cancer, Renal Cell Cancer, Kidney Cancer, Skin Cancer, Non Small Cell Lung Cancer, NSCLC, Anaplastic Lymphoma Kinase Genomic Tumor Aberrations, ALK Genomic Tumor Aberrations
Study phase:
Physician name:
Apostolia Tsimberidou
Department:
Investigational Cancer Therapeutics
For general questions about clinical trials:
1-866-379-1063
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