Study #2023-0970
A global pivotal study in participants with KRAS G12C-mutant, locally advanced or metastatic non-small cell lung cancer comparing first- line treatment of LY3537982 and Pembrolizumab vs placebo and Pembrolizumab in those with PD-L1 expression .50% or LY3537982 and Pembrolizumab, Pemetrexed, Platinum vs Placebo and Pembrolizumab, Pemetrexed, Platinum regardless of PD-L1 expression
MD Anderson Study Status
Enrolling
Treatment Agent
LY3537982, Pembrolizumab, Cisplatin, Carboplatin, Pemetrexed, Placebo
Description
The purpose of this study is to assess if adding LY3537982 in combination with standard of care anti-cancer drugs is more effective than standard of care in participants with untreated advanced NSCLC. NSCLC must have a change in a gene called KRAS G12C. Study participation, including follow-up, could last up to 3 years, depending on how you and your lung cancer are doing.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Study phase:
Phase III
Physician name:
Marcelo Vailati Negrao
Department:
Thoracic/Head & Neck Medical Oncology
For general questions about clinical trials:
1-844-335-2276
Help #EndCancer
Give Now
Donate Blood
Our patients depend on blood and platelet donations.
Shop MD Anderson
Show your support for our mission through branded merchandise.