Distinct classes of fibroblasts in tumors play opposing roles, promoting or restraining pancreatic cancer growth
Researchers at The University of Texas MD Anderson Cancer Center have discovered that two distinct classes of cancer-associated fibroblasts (CAFs) accumulate in the pancreatic tumor microenvironment and play opposing roles to promote and restrain pancreatic cancer development.
The preclinical findings suggest that appropriately targeting these unique CAF populations may offer strategies to improve the use of other treatments, such...
MD Anderson launches James P. Allison Institute to usher in new era for immunotherapy
The University of Texas MD Anderson Cancer Center today launched the James P. Allison Institute, a visionary research and innovation...
Neal Copeland and Nancy Jenkins elected Fellows of the AACR Academy
Neal G. Copeland, Ph.D., and Nancy A. Jenkins, Ph.D., both professors of Genetics at The University of Texas MD Anderson Cancer Center...
Computational approach enables spatial mapping of single-cell data within tissues
A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.
The study was published today in Nature Biotechnology and will...
