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Appointment Information
RESEARCH PLATFORM FOR
THE MOON SHOTS PROGRAM
The Translational Molecular Pathology Immunoprofiling Laboratory (TMP-IL) Moon Shot® platform designs, validates and analyzes cancer immune-related markers in clinical samples to explore the intricate immune network of tumors. TMP-IL is highly involved in the immune monitoring of innovative clinical trials through MD Anderson’s strategic alliances pipeline as well as through investigator-initiated studies accelerating the pace of biomarker discovery. TMP-IL has gained national recognition through its role as a Cancer Immune Monitoring and Analysis Center (CIMAC).
Cara Haymaker, Ph.D.
Director; Assistant Professor, Translational Molecular Pathology
Luisa Maren Solis, M.D.
Immunohistochemistry and Digital Pathology Lab Director; Assistant Professor, Translational Molecular Pathology
Edwin Roger Parra-Cuentas, M.D., Ph.D.
Digital Pathology and Multiplex Assays Lab Director; Assistant Professor, Translational Molecular Pathology
TMP-IL works in collaboration with multi-disciplinary MD Anderson clinical and translational investigators for immunology, pathology and genomics assays. This work aims to complement the groundbreaking work of clinical investigators providing access to cutting-edge knowledge and state-of-the-art technology for immunoprofiling. Additionally, TMP-IL coordinates its efforts with the APOLLO platform to analyze the longitudinal samples it collects including the Rare Tumor Profiling Initiative that aims to perform molecular profiling for up to 1,500 patients.
The functions of the platform include:
Ignacio Wistuba, M.D., chair of Translational Molecular Pathology and co-leader of the APOLLO Moon Shot research platform, discusses how the Translational Molecular Pathology Immunoprofiling Laboratory is working with APOLLO to analyze longitudinal samples from the Rare Tumor Initiative.
Learn moreThe Translational Molecular Pathology Immunoprofiling Laboratory is part of MD Anderson’s operational priority to perform molecular profiling and provide access to data, data analytics and meaningful data integration for rare tumors.
The Cancer Immune Monitoring and Analysis Centers - Cancer Immunologic Data Commons (CIMAC-CIDC) Network is an NCI Cancer Moonshot initiative launched in September 2017 whose goal is to identify biomarkers for optimizing immunotherapeutic strategies for cancer patients. CIMACs, CIDC and clinical trial investigators design and conduct analyses correlating outcomes from immunotherapy trials with biomarkers. CIMACs perform bioassays on biospecimens from immunotherapy clinical trials led by a range of NCI trial organizations. The biomarker data are transferred from the CIMACs to the CIDC, along with clinical data elements from the clinical trial groups, to enable the correlative analyses.
