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MOON SHOTS PROGRAM
Melanoma affects all ages and is one of the most common cancers in older adolescents and young adults. It's largely caused by exposure to ultraviolet radiation (UVR), either from direct sunlight or from tanning bed use. According to a study in the journal Cancer Epidemiology, Biomarkers & Prevention, sustaining five or more blistering sunburns while young increases one's melanoma risk by 80 percent.
The Melanoma Moon Shot® is revolutionizing the conventional medical research approach to rapidly adapt pre-clinical findings into patient treatment options.
Michael Davies, M.D., Ph.D.
Associate Professor, Melanoma Medical Oncology
Jeffrey E. Gershenwald, M.D.
Professor, Surgical Oncology
Hussein A. Tawbi, M.D., Ph.D.
Professor, Melanoma Medical Oncology
Jennifer Wargo, M.D.
Associate Professor, Surgical Oncology
"One of our key goals is to spread awareness about this disease and the factors that contribute to it, so that ultimately we can reduce the incidence of melanoma."
Listen as Moon Shot® co-leader Michael Davies, M.D., Ph.D., shares how your support can help accelerate new treatments and clinical trials for patients with this disease.
Researchers from MD Anderson found specific intestinal microbiota signatures correlate with high-grade adverse events and response to combined CTLA-4 and PD-1 blockade treatment. The study, published in Nature Medicine, also identified a potential new strategy to treat toxicity – while maintaining response – to combined immune checkpoint blockade through either IL-1R inhibition or manipulation of the gut microbiota.
Learn moreMelanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. Researchers at MD Anderson report in Cancer Discovery that the heavy reliance of these tumors on a specific metabolic pathway presents a potentially new therapeutic against these lethal tumors.
