Multiple Endocrine Neoplasia Diagnosis

MD Anderson offers the most advanced methods and technology to diagnose multiple endocrine neoplasia (MEN).

If other people in your family have or had multiple endocrine neoplasia (MEN) or other inherited diseases, MD Anderson offers advanced genetic testing to see if you are at high risk. Genetic testing of a blood sample can identify MEN1 gene mutations in many people with symptoms. A positive test result can confirm a diagnosis or identify family members at risk of developing MEN1. However, a negative test result cannot definitively rule out MEN1 in patients when a mutation has not been identified in another family member.

Genetic testing is offered to adults. Children with symptoms are also tested on case-by-case basis. Testing is typically not done on children who don't have symptoms because there are currently no preventive treatments. A genetic counselor will discuss testing with you and your family, answer any questions and help you make an informed decision regarding testing.

If you have symptoms that may signal multiple endocrine neoplasia, your doctor will examine you and ask you questions about your health and your family history.

One or more of the following tests may be used to find out if you have MEN. These tests also may be used to find out if treatment is working.

• Blood tests
• Urine tests
• Imaging tests, which may include:
  • CT or CAT (computed axial tomography) scans
  • MRI (magnetic resonance imaging) scans